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CAR T-cell (chimeric antigen receptor) therapy, a promising form of immunotherapy, involves reprogramming the patient’s T cells to enhance their ability to identify and combat antigens on the surface of cancer cells.

However, this therapy, which is currently approved for the treatment of leukemia and lymphoma, has a significant downside. During the process of destroying cancer cells, many of the engineered T cells get contaminated with residual cancer antigens, leading them to attack fellow T cells. This eventually results in a decrease in the body’s population of cancer-fighting cells, opening the door for a recurrence of cancer.

A new Yale study, however, has identified a way to tame the self-destructive tendencies of these killer T cells. Simply fusing a molecular tail onto the engineered T cells used in therapy, researchers say, can inhibit their proclivity to attack each other. The study was published July 27 in the journal Nature Immunology.

This technology promises to revolutionize spacecraft design, save space, and enhance communication capabilities, opening up new frontiers for exploration and discovery.

In the vast expanse of space, engineers constantly push the boundaries of innovation to do more with less. Today’s small spacecraft is equipped with sensors, guidance and control systems, and operating electronics, making efficient use of every available space. But what if we could take it a step further and revolutionize the way we integrate electronics into these spacecraft?

Recently, aerospace engineer Beth Paquette and electronics engineer Margaret Samuels from NASA’s Goddard Space Flight Center in Greenbelt, Maryland,… More.

Continue reading “NASA engineers test revolutionary printed electronics in space” »

Researchers at NYU College of Dentistry’s Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings of the National Academy of Sciences (PNAS).

The innovative therapy, tested in cells and animals, is made possible by the discovery of the precise region where a regulatory protein binds to the NaV1.7 sodium ion channel to control its activity.

“Our study represents a major step forward in understanding the underlying biology of the NaV1.7 sodium ion channel, which can be harnessed to provide relief from chronic pain,” said Rajesh Khanna, director of the NYU Pain Research Center and professor of molecular pathobiology at NYU Dentistry.

The manufacturing and industrial sector is currently undergoing a transformation with the advent of generative AI, the metaverse and web3 technology. Organizations can now use cutting-edge tools and solutions to streamline operations, increase efficiency, and enhance the customer experience.

Let’s explore the ways in which the metaverse, AI and web3 technology are transforming manufacturing and industrial organizations and what the future of this sector may look like as a result.

The integration of metaverse technology into the manufacturing sector has the potential to revolutionize the way companies operate, providing new opportunities for optimization, innovation, and growth.

Researchers at the University of Texas at El Paso (UTEP) have created a supercapacitor with a record level of energy storage, marking a significant advancement in the field.

Discover the groundbreaking world of generative AI and how it differs from traditional AI, unlocking new realms of creativity, innovation, and limitless possibilities.

From Hollywood, to technological innovation, A.I. has been baked into the sociological subconscious for decades. With a new contemporary push, artificial intelligence is capturing the human imagination and pushing it to new depths. We’re hoping to explore all those weird intricacies here.

Big thanks to @ThenNow for lending his voice on the quote within “The Psychoanalysis of Artificial Intelligence”. I’m sure you’re more than ahead of me, but do go check him out!

Continue reading “The Philosophy of Artificial Intelligence” »

In a ground-breaking experiment, researchers from the University of Groningen collaborated with their peers from Nijmegen and Twente universities in the Netherlands, and the Harbin Institute of Technology in China. Together, they confirmed the existence of a superconductive state that was first predicted in 2017.

Their findings, which demonstrate evidence for a unique form of the FFLO superconductive state, were recently published in the journal Nature. This breakthrough has the potential to be impactful, particularly within the field of superconducting electronics.

Bill Gates explains the risks associated with AI and argues that they are manageable. Innovations often create new risks that need to be controlled.