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After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex ‘anti-tumor antibiotic’ known to be highly effective against cancer cells as well as drug-resistant bacteria, and have reproduced it synthetically in the lab for the first time.

This major breakthrough and world-first could hail a new era in the design and production of new antibiotics and anticancer agents.

The ‘super substance’ — kedarcidin — was discovered in its natural form by a pharmaceutical company when they extracted it from a soil sample in India almost 30-years-ago. Soil is the natural source of all antibiotics developed since the 1940s but in order for them to be developed as potential drug treatments they must be produced via chemical synthesis.

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ETH researchers have cooled a nanoparticle to a record low temperature, thanks to a sophisticated experimental set-up that uses scattered laser light for cooling. Until now, no one has ever cooled a nanoparticle to such low temperatures in a photon cage. Dominik Windey and René Reimann – a doctoral student and postdoc in the group led by Lukas Novotny, Professor of Photonics – have succeeded in cooling a 140 nanometre glass bead down to a few thousandths of a degree above absolute zero.

The researchers recently published details of their work in the journal Physical Review Letters. Their breakthrough came in the form of a sophisticated experimental set-up involving optical tweezers, whereby a nanoparticle can be made to levitate with the aid of a laser beam. The group has already used the same optical tweezers in previous work, in which they caused a nanoparticle to rotate around its own axis at extremely high speed.

After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex ‘anti-tumour antibiotic’ known to be highly effective against cancer cells as well as drug-resistant bacteria, and have reproduced it synthetically in the lab for the first time.

This major breakthrough and world-first could hail a new era in the design and production of new antibiotics and anticancer agents.

The ‘super substance’—kedarcidin—was discovered in its natural form by a pharmaceutical company when they extracted it from a soil sample in India almost 30-years-ago. Soil is the natural source of all antibiotics developed since the 1940s but in order for them to be developed as potential drug treatments they must be produced via chemical synthesis.

Continue reading “Scientists are world’s firsts to reproduce complete copy of ‘anti-tumour antibiotic’” »

NASA has announced the 18 projects awarded funding in its NASA Innovative Advanced Concepts (NIAC) programme.

St. Jude researchers license technology to Mustang Bio in hopes of bringing treatment to market.

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About a billion people around the world lack access to safe drinking water. Desalinating salty water into drinkable water can help to fill this dangerous gap. But traditional desalination systems are far too expensive to install and operate in many locations, especially in low-income countries and remote areas.

Now researchers at the University of Maryland’s A. James Clark School of Engineering have demonstrated a successful prototype of one critical component for affordable small-scale desalination: an inexpensive solar evaporator, made of wood. The evaporator generates steam with high efficiency and minimal need for maintenance, says Liangbing Hu, associate professor of materials science and engineering and affiliate of the Maryland Energy Innovation Institute.

The design employs a technique known as interfacial evaporation, “which shows great potential in response to global water scarcity because of its high solar-to-vapor efficiency, low environmental impact, and portable device design with low cost,” Hu says. “These features make it suitable for off-grid water generation and purification, especially for low-income countries.”

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Firearms makers have resisted Silicon Valley-sponsored digital innovation that could transform public safety.

Circa 2017

Chinese scientists accomplish the feat of teleporting a photon to a satellite hundreds of miles above Earth.

Continue reading “Scientists Make a Breakthrough in Teleportation” »