Lifeboat Foundation

Let the record show that the current COVID-19 vaccines work, and they work well. But what is the next step in vaccine development, especially amid increasing rates of breakthrough infections and emergence of variants of concern?

In a new Northwestern Medicine study in mice, researchers took one of the current vaccines, which is based on the novel coronavirus’s infamous spike protein, and added a different antigen, the nucleocapsid protein, to form a new, potentially improved version of the COVID vaccine. The nucleocapsid protein, which is an internal RNA-binding protein, may help kick the immune system into high gear much more quickly than the spike protein is capable of since it is among the most rapidly and highly expressed proteins in coronaviruses.

“At this point, we’re just trying to figure out ‘What should the 2.0 vaccines be?’” said senior and corresponding study author Pablo Penaloza-MacMaster, an assistant professor of microbiology-immunology at Northwestern University Feinberg School of Medicine. “It seems like adding nucleocapsid to the vaccine renders it more protective, relative to having only the spike.”

In a study recently published in Nature Nanotechnology, a research group led by Prof. Du Haifeng and Dr. Tang Jin from High Magnetic Field Laboratory, Hefei Institutes of Physical Science (HFIPS), reported a scientific breakthrough after they found skyrmion bundles, a new family member of topological magnetic structures.

With the help of Lorentz transmission electron microscopy (Lorentz-TEM), the research group clarified, for the first time, a type of magnetic quasiparticles with arbitrary topological charges Q, and then further realized current driven dynamic motion of skyrmion bundles.

Skyrmion, a vortex-like localized chiral topological magnetic structure, has a potential to be the information carrier applied in future high-performance spintronic devices. The topological charge is a fundamental parameter of magnetic domains and determines their topology-related properties. Among the topological structures including skyrmions, merons, vortex, and skyrmion bubbles, the topological charges are both one or smaller than one. Although theory has proposed “skyrmion bags” and “high-order skyrmions” as multi-Q topological magnetic structures, their experimental observations remain elusive.

I think I posted about the work in Texas, but here is more work.

Israeli and American researchers have discovered a nanobody cocktail that could neutralize coronavirus, including the Delta mutation.

Nanobodies are single domain antibodies derived from llamas — or other members of the camel family.

Continue reading “Israeli researchers say llama nanobodies could help stop COVID” »

Development of the aircraft isn’t focused solely around military use; Hermeus is intent on bringing innovation to commercial flight, too. “While this partnership with the US Air Force underscores US Department of Defense interest in hypersonic aircraft, when paired with Hermeus’ partnership with NASA announced in February 2,021 it is clear that there are both commercial and defense applications for what we’re building,” said Hermeus CEO and co-founder AJ Piplica.

Hermeus’ Quarterhorse is a hypersonic aircraft that can fly at Mach 5 speeds, or 3,000 mph—fast enough to go from the US to Europe in 90 minutes.

Continue reading “Flight Testing Will Soon Start on the World’s Fastest Reusable Aircraft” »

Launched Aug. 10 1966, Lunar Orbiter 1 was a mission that would set the mold for future planetary science missions thanks to a complicated camera system.

Circa 2014 😗 mind uploading soon.

In a neuroscience breakthrough, the duo pioneered a real-life version of Inception.

A video about Walt Disney Imagineering has revealed a new shot of the lightsaber.

🌊

Why are innovation cycles and business growth linked so closely? We explore waves of creative destruction across history.

No, it’s not forbidden to innovate, quite the opposite, but it’s always risky to do something different from what people are used to. Risk is the middle name of the bold, the builders of the future. Those who constantly face resistance from skeptics. Those who fail eight times and get up nine.

(Credit: Adobe Stock)

Fernando Pessoa’s “First you find it strange. Then you can’t get enough of it.” contained intolerable toxicity levels for Salazar’s Estado Novo (Portugal). When the level of difference increases, censorship follows. You can’t censor censorship (or can you?) when, deep down, it’s a matter of fear of difference. Yes, it’s fear! Fear of accepting/facing the unknown. Fear of change.

Continue reading “Innovation is a risk!” »