Open Longevity Foundation has announced Open Genes, a database of longevity-associated genes and a tool for future anti-aging therapy development. The full press release is included here. Open Longevity Foundation released a novel database of genes involved […].
The year is 2021, and journalism is dead. It does not particularly matter what your personal beliefs or creed are, at this point it has become blindingly apparent that the vast majority of the media are not overly concerned with the truth.
In aging mouse livers, 40% of elongating RNA polymerases are stalled, biasing transcriptional output dependent on gene length. This transcriptional stress appears to be caused by endogenous DNA damage.
https://youtube.com/watch?v=3AQPgchedUw
This video explores aliens, mind uploading to other species (like in Avatar), genetic engineering, and future robots. Watch this next video about digital immortality: https://youtu.be/sZdWN9pbbew.
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SOURCES:
• https://en.wikipedia.org/wiki/Eagle_eye#:~:text=Eagles%20hav…0developed, see%20from%205%20feet%20away.
• https://vcahospitals.com/know-your-pet/how-dogs-use-smell-to…has%20been, 10%2C000%20times%20better%20than%20people.
• https://www.scientificamerican.com/article/small-animals-liv…ion-world/
• https://en.wikipedia.org/wiki/Human_cloning.
Continue reading “When WIll We Upload Our Minds To Other Species?” »
Source: Penn State
Understanding the neural interface within the brain is critical to understanding aging, learning, disease progression and more. Existing methods for studying neurons in animal brains to better understand human brains, however, all carry limitations, from being too invasive to not detecting enough information.
A newly developed, pop-up electrode device could gather more in-depth information about individual neurons and their interactions with each other while limiting the potential for brain tissue damage.
By ten years.
An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.
Associated with exceptional longevity, carriers of healthy mutant genes, like those living in blue zones of the planet, often live to 100 years or more and remain in good health. These individuals are also less prone to cardiovascular complications. Scientists believe the gene helps to keep their hearts young by protecting them against diseases linked to aging, such as heart failure.
Continue reading “Anti-aging gene shown to rewind heart age” »
Summary: Rilmenidine, a drug commonly prescribed to help treat hypertension can help slow the effects of aging and extend lifespan, a new study reports.
Source: University of Liverpool.
Researchers have found that the drug rilmenidine can extend lifespan and slow aging.
Summary: A subset of taste cells may play a key role in the body’s immune response to harmful oral microbes. The findings could help taste loss associated with infections, aging, and dysregulation of the oral microbiome caused by chemotherapy.
Source: University of Nebraska Lincoln.
Taste cells are heavily exposed to the microbes in the mouth, but their role in helping the body respond to those microbes has not yet been studied in detail.
Improving intelligence has preoccupied society since French psychologist Alfred Binet devised the first IQ test. Since then, the notion that intelligence can be calibrated has opened new avenues into figuring out how it can also be increased.
Psychological scientists have been on the front lines of modifying intelligence. So much intelligence is genetically determined, it is, to a large extent, hereditary. But there are still some areas in which it can be malleable.
Intelligence is generally divided into two categories: fluid intelligence and crystallized intelligence. Fluid intelligence is the ability to reason in an abstract way and solve problems. Someone who can come up with dozens of new uses for, say, a toothbrush would demonstrate superior fluid intelligence. And this is exactly the kind of intelligence that tends to diminish as we grow older. The acquisition of intellectual skills, or the ability to read and comprehend, is known as crystallized intelligence, and this form tends to improve as we age.
Cellular reprogramming builds on the Nobel Prize-winning work of Shinya Yamanaka, who showed that adult cells could be transformed back into stem cells by exposing them to a specific set of genome-regulating proteins known as transcription factors. The Salk team’s innovation was to reduce the exposure times to the so-called Yamanaka factors, which they found could reverse epigenetic changes to the cells without reverting them to stem cells.
While the approach led to clear increases in lifespan in prematurely aging mice, the fact that no one had been able to replicate the result in healthy mice since then raised doubts about the approach. “Different groups have tried this experiment, and the data have not been positive so far,” Alejandro Ocampo, from the University of Lausanne in Switzerland, who carried out the original Salk experiments, told MIT Technology Review.
But now, Rejuvenate Bio claims that when they exposed healthy mice near the end of their lives to a subset of the Yamanaka factors, they lived for another 18 weeks on average, compared to just 9 weeks for those that didn’t undergo cellular reprogramming.
