Lifeboat Foundation

A new study in an animal model of aging indicates a potential reason for why women who have early menopause or other genetic conditions affecting the reproductive system are more prone to develop cardiovascular disease, diabetes, and dementia.

The new study, led by researchers from the University of Pittsburgh and UPMC and published in the journal Aging Cell, found that disrupting a process called meiosis in C. elegans reproductive cells caused a decline in the worms’ health and triggered an accelerated aging gene signature similar to that of aging humans.

“This study is exciting because it’s the first direct evidence that manipulating the health of reproductive cells leads to premature aging and a decline in healthspan,” said senior author Arjumand Ghazi, Ph.D., associate professor of pediatrics, developmental biology, and cell biology and physiology at Pitt and UPMC Children’s Hospital of Pittsburgh. “The implications of this finding are profound: It suggests that the status of the reproductive system is important not simply to produce children, but also for overall health.”

People affected by the lethal glioblastoma cancer only live for 12–18 months after diagnosis.

A global trial that began in 2007 has confirmed that a vaccine for the treatment of the most lethal brain cancer can give patients years of extended life.

Glioblastoma is not only the most common form of brain cancer but is also one of the deadliest. People affected by the disease only live just 12–18 months after the diagnosis, or even less.

Continue reading “Vaccine for lethal brain cancer extends the lifespan of patients” »

Bacteria that cause leprosy are shown to safely grow and regenerate the liver, in animal experiments.

Hope, hype, and self-experimentation collided at an exclusive conference for ultra-rich investors who want to extend their lives past 100. I went along for the ride.

This is primarily about Rejuvant or AKG trials. When they first reported an 8 year age difference I did not truly believe it as that would mean I could take it, de-age, then age a bit, then just take it again. The tests however are ongoing and will feature people who are biologically older than their calendar age. There is also mention of 110 drugs/supplements that do “something” to mice. That would be quite a stack to take.

Dr Brian Kennedy presents potential interventions for extend our healthspan. Among them, Rejuvant – a CaAKG supplement which contain calcium + alpha-ketoglutarate shows better response for people who has biological age older than chronological age.

Continue reading “Potential Interventions For HUMAN LONGEVITY, CaAKG Is More Effective for People w/Accelerating Aging” »

Advancing Novel Therapeutic Interventions For Unmet Medical Needs — Dr. Michael Hufford, Ph.D., Co-Founder and CEO, LyGenesis; Interim CEO, Morphoceuticals; Scientific Advisor, Juvenescence.

Dr. Michael Hufford, Ph.D. is the Co-Founder and the Chief Executive Officer of LyGenesis (https://www.lygenesis.com/), a clinical-stage cell therapy company that transforms patient’s lymph nodes into bioreactors capable of growing functioning ectopic organs. He also serves as the Interim CEO of Morphoceuticals (https://www.morphoceuticals.com/) a company focused on modifying electric potentials in cells and tissues for a variety of applications in regenerative medicine, from improving amputation stump health and limb regeneration, to organogenesis, to creating a bioelectric atlas where numerous disease indications may be corrected.

Continue reading “Dr. Michael Hufford, PhD — Advancing Novel Therapeutic Interventions For Unmet Medical Needs” »

The maniacally focused founder of Insilico Medicine is going all in on AI to discover new medicines and extend lifespan.

But researchers are now using artificial intelligence to accelerate parts of that process by orders of magnitude. The same kind of technology that recognizes your face or autocompletes your emails can potentially add years to your life, experts say.

2022 https://cryonics.org/wp-content/uploads/2022/11/CI_NEWS-2022-03.pdf.

This issue features:
* President’s Report — New Science Advisory Board.
* 2022 AGM Photos.
* Board of Directors Winners.
* Scale Model CI Cryostats for Sale.
* Cryonics Survey.
* Robert Ettinger’s YOUNIVERSE — Chapter 5
* Latest Cryonics & Life Extension News from Around the Web.

Sea anemones are seemingly immortal animals. They seem to be immune to aging and the negative impacts that humans experience over time. However, the exact reasons for their eternal youth are not completely understood.

The genetic fingerprint of the sea anemone Nematostella vectensis reveals that members of this incredibly ancient animal phylum employ the same gene cascades for neural cell differentiation as more complex organisms. These genes are also in charge of maintaining the balance of all cells in the organism during the anemone’s lifetime. These findings were recently published in the journal Cell Reports by a group of developmental biologists headed by Ulrich Technau of the University of Vienna.

Almost all animal organisms are made up of millions, if not billions, of cells that join together in intricate ways to create specific tissues and organs, which are made up of a range of cell types, such as a variety of neurons and gland cells. However, it is unclear how this critical balance of diverse cell types emerges, how it is regulated, and if the different cell types of different animal organisms have a common origin.