Lifeboat Foundation

The recent advances in machine learning and artificial intelligence, coupled with increases in computational power, have led to a lot of interest and hype in longevity biotechnology 30114–2). Hundreds of data scientists and companies are taking advantage of this hype to propel research and discovery of new technologies in aging research.

One of the major new areas in aging research are biomarkers of aging that give the true biological age of humans that may be different from their chronological age. One of the most advanced biomarkers of aging are deep aging clocks that can help researchers predict biological age as well as mortality of humans. In 2013, Steven Horvath published an article called ‘DNA methylation age of human tissues and cell types,’ in which he outlined the development of a multi-tissue predictor of age that allows for the estimation of the DNA methylation age of most tissues and cell types. He also formed an aging clock that can be used to address questions in developmental biology, cancer, and aging research.

There have been several more studies on such clocks since 2013. For example, I was part of a team in 2016 and we published a study on the first deep aging clock titled ‘Deep biomarkers of human aging: Application of deep neural networks to biomarker development.’ Since our study was published, many other aging clocks that can predict age as well as mortality rapidly entered into many industries. it is clear that there is a boom in the longevity biotechnology industry and huge progress in aging research is expected to be made in the next few years. AI-based aging clocks provide a very good entry point for the insurance companies to get into the field of aging research and actually contribute while protecting their business and innovating in science and technology.

Chula Medicine has successfully invented RED-GEMs (REjuvenating DNA by GEnomic Stability Molecules) that can reverse aging in lab animals. With human trials targeted within two years, the medical breakthrough is aimed to treat various age-related conditions and illnesses and bring back youthfulness in this aging society.

Rhiannon Zos Sol’RhāTalked to her once on a conference brilliant woman.

2 Replies.

Continue reading “Is Immortality Possible or Is Aging Inevitable?” »

Overall, the results indicate that failure-oriented people are more likely to make poor health choices, presumably due to a lack of proper motivation. When looking at the cause of death for each author, results also showed a strong link between failure motivation and whether or not the death could be considered preventable.

As we can see from this study and many other similar studies, people who expect failure are generally less effective in maintaining good health habits. On the other hand, a positive outlook can play a powerful role in our health decisions. Healthy behaviors include regular exercise, good nutrition, an active lifestyle, and full compliance with medical advice., all of which require strong motivation to ensure we stay the course. A positive mindset also makes us avoid unhealthy activities such as drinking, smoking, and prolonged inactivity. People who develop a failure mindset, whether due to health setbacks, hopelessness, or a general sense of fatalism, often make lifestyle decisions that can undermine their overall health and, as a result, their longevity.

Full Story:

Continue reading “Don’t Let The Old Man In: How To Develop A Longevity Mindset And Fight Psychological Aging?” »

A team of Juntendo University researchers tested a vaccine in mice that appeared to suppress the growth of so-called zombie cells.

What exactly is Obesity?

Obesity is known to cause cardiometabolic diseases like hypertension and diabetes but attributing these diseases to merely an overabundance of fat is a simplification. On a basic level, fat acts as a receptacle to store energy, but upon a closer look it is an essential actor in vital bodily processes like the immune response, the regulation of insulin sensitivity, and maintenance of body temperature. In a review published in the journal Cell on February 3rd, 2022, researchers argue that the negative health effects of obesity stem not simply from an excess of fat but from the decline in its ability to respond to changes, or in other words, its plasticity.

The makeup and functioning of this tissue changes in response to weight fluctuations and aging. As fat declines in plasticity due to aging and obesity, it loses its ability to respond to bodily cues. In the current model of this phenomenon, the rapid growth of adipose tissue outpaces its blood supply, depriving the fat cells of oxygen and causing the accumulation of cells that no longer divide. This leads to insulin resistance, inflammation, and cell death accompanied by the uncontrolled spill of lipids from these cells.

Continue reading “New Research Finds That With Obesity, the Problem Isn’t an Excess of Fat but Its Loss of Function” »

New South Wales has again received an overwhelming response from aspiring developers of wind, solar and storage projects, with more than 34GW of proposals for the South-West Renewable Energy Zone, more than 10 times its likely capacity.

The state government, through its newly formed Energy Corporation of NSW, ran a registration of interest process in October and November for the south-west region, one of at least five REZs planned to help replace the ageing coal fleet over the coming decade.

“There were 49 registrations totalling over 34 gigawatts from potential generation and storage projects – thirteen times the intended capacity for the South-West REZ, which will be no less than 2.5 gigawatts,” James Hay, the CEO of Energy Corp, said in a statement on Friday.

Excerpt taken from a conversation held between Peter Diamandis and Mark Hyman.

In the description of the video is the link of the original video with the entire conversation.

Continue reading “Peter Diamandis: never getting old is coming (clip from a talk w/ Mark Hyman) | S/T en Español” »

The so-called ‘longevity sirtuin’ Sirt6 shows both lifespan and healthspan benefits and a new paper digs deeper into just why that is.