Lifeboat Foundation

It’s the BIG one! The FINAL LEVEL on the Kardashev Scale! In this video, Unveiled discovers what the world would be like if humanity could complete the Kardashev Scale and become the most advanced civilisation it’s possible to be… This goes beyond gods and monsters, to the incredible, immortal heart of the omniverse!

Let us know what you think in the comments!

Continue reading “What If Humanity Was a Type VII Civilization? | Unveiled” »

In one of the mysteries of mammalian development, every cell in the early female embryo shuts down one of its two copies of the X chromosome, leaving just one functional. For years, the mechanics behind this X chromosome inactivation have been murky, but scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have now taken a major step forward in understanding the process.

Their findings, based on research on mouse stem cells, upend previous assumptions about how X inactivation is initiated in female embryos and could lead to new ways to treat some genetic disorders, as well as a better understanding of how genes on other chromosomes are silenced.

“X inactivation is one of the most fundamentally important processes in development, and I think this study is a slam dunk in finally understanding it,” said Kathrin Plath, a professor of biological chemistry and senior author of the paper, published in the journal Cell.

https://www.youtube.com/watch?v=X1TYqoR-qVA

We explore human enhancement and personal performance hacking with Matt Ward (@mattwardio), host of The Disruptors podcast, startup investor, adviser, and business innovation consultant. Matt and I thought it would be fun to do two episodes, one here on MIND & MACHINE and the other on The Disruptors, where we explore what we’ve learned, the ideas we’ve formed and our takeaways across all these different fields that we cover.

So with this episode here on MIND & MACHINE, we focus on human enhancement — technologies that are extending lifespan and enhancing human capability. Then we get into what Matt and I are doing currently to maximize our own performance capabilities — our ability to think more clearly, to live more energetic vibrant lives… which is all heavily informed by all these amazing guests across these different fields that we explore.

Continue reading “Human Enhancement & Personal Performance Hacking with Matt Ward of ‘The Disruptors’” »

Taking a daily multivitamin for 3 years is associated with a 60% slower cognitive aging, with the effects particularly pronounced in patients with cardiovascular (CVD) disease, new research suggests.

In addition to testing the effect of a daily multivitamin on cognition, the COSMOS-Mind study also examined the effect of cocoa flavonols, but showed no beneficial effect.

The results “may have important public health implications, particularly for brain health, given the availability of multivitamins and minerals and their low cost and safety,” said research researcher Laura D. Baker, PhD, professor, Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

One-minute-long excerpt of the intervention of Professor David Sinclair during an event organized by the SALT Fund, that took place in October.

In this excerpt, Professor Sinclair talks about the work done in his Lab at Harvard University on partial cellular reprogramming and rejuvenation.

Continue reading “David Sinclair on partial cellular reprograming and rejuvenation (with S/T in Spanish)” »

Scientists surveyed dozens of species’ genomes to uncover keys to longevity.

Innovation At The Intersection Of Cancer & Aging, Via Digital Health & Behavioral Sciences — Dr. Corinne Leach, Ph.D. American Cancer Society

Dr. Corinne Leach, PhD, MPH, MS, is a gerontologist, digital health strategist, and behavioral scientist, who serves as the Senior Principal Scientist, Behavioral Research, at the American Cancer Society (https://www.cancer.org/).

Continue reading “Dr Corinne Leach, Ph.D. — Gerontology, Digital Health, Behavioral Science — American Cancer Society” »

Becoming Immortal through Mind Uploading sounds like something that’ll only be possible around the 2100’s. But amazingly, a group of scientists at Nectome are working on giving us the ability to live forever inside of a computer simulation by the end of this decade for around 10000$.

Ray Kurzweil, director of engineering at Google, has long predicted that people will be able to upload their entire brains to computers and become digitally immortal by 2045. Kurzweil made this claim for many years, e.g. during his speech in 2013 at the Global Futures 2045 International Congress in New York, which claims to subscribe to a similar set of beliefs. Mind uploading has also been advocated by a number of researchers in neuroscience and artificial intelligence, such as the late Marvin Minsky.
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Continue reading “Becoming Immortal for 10,000$? — Upload Your Mind THIS DECADE!” »

Aging affects everybody, so it’s easy to understand why so much scientific attention is focused on studying it. Scientists in Canada now claim to have found that telomeres play a different role in cellular aging than previously thought.

One of the main points of interest in anti-aging biology are what’s known as telomeres. These are sections of “junk” DNA that form caps on the ends of chromosomes, protecting important genetic information from damage when a cell divides. But a piece of the telomere is eroded away with each cell division, and when it gets too short the cell stops dividing entirely, entering a dormant state known as senescence. The build-up of these senescent cells contributes to a range of symptoms we associate with aging, such as frailty and age-related diseases.

The implication of this model is that telomeres take on a pre-emptive protection role – they signal to cells to stop dividing as soon as one telomere wears out. But there is evidence to suggest that cell division can continue with as many as five dysfunctional telomeres.