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Archive for the ‘life extension’ category: Page 360

May 2, 2019

Israel fast becoming world hub of aging industry

Posted by in categories: business, life extension

Eric Kilhstrom (Director of Aging Analytics Agency and former Interim Director of the £98 million Healthy Ageing Industrial Strategy Challenge Fund) is interviewed about the agency’s recent “Longevity Industry in Israel Landscape Overview 2019” report.


New report shows that Israel’s academic and business ecosystem is the optimal base for an internationally recognized longevity industry hub.

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May 1, 2019

Here’s an image of Max More, Natasha Vita-More, Jim Strole, Bernadeane, and myself with the final version of our XPRIZE work at their event yesterday

Posted by in categories: biotech/medical, government, life extension, policy

We submitted the Longevity Peace Prize, worth $5 million dollars to be awarded to any longevity activist(s) in the next 5 years who can get a major world government or the UN to declare “aging a disease” as a policy and to help reverse regulatory hurdles on life extension research. Hopefully, this early version of a prize may one day become reality. https://xprize.org/

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May 1, 2019

Rejuvenation Roundup April 2019

Posted by in category: life extension

April is gone, and before we move on to May, let’s take a look back at the highlights of last month in the rejuvenation world.

LEAF News

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May 1, 2019

New video from Undoing Aging 2019: Judy Campisi, Professor at the Buck Institute for Research on Aging, presenting her work on taming cellular senescence, the source of chronic inflammation implicated in major age-related diseases

Posted by in categories: biotech/medical, life extension

undoing-aging.org/…/judy-campisi-presenting-at-undoing-agin…

More info on Forever Healthy: forever-healthy.org

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Apr 30, 2019

The April Journal Club will be discussing the recent paper from the Salk Institute

Posted by in categories: biotech/medical, life extension

The findings, published in the journal Nature Medicine, showcase a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome. This treatment provides an important insight into the molecular pathways involved in accelerated aging, as well as how to reduce toxic proteins via gene therapy. The researchers hope to translate this therapy to humans to potentially provide a cure for progeria as well as possibly slowing down the aging process to delay the onset of age-related diseases in everyone.

Link to paper: https://www.nature.com/articles/s41591-019-0343-4

Abstract.

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Apr 30, 2019

You Thought Ageing Can’t Be Reversed? Well, Think Again!

Posted by in category: life extension

We didn’t see that coming.

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Apr 30, 2019

NMN Improves Cognitive Function in Aged Mice

Posted by in categories: biotech/medical, life extension, neuroscience

Researchers have tested nicotinamide mononucleotide on aged mice to see if it can help reverse age-related cognitive decline by improving blood flow in the brain.

The brain is a hungry organ

Healthy brain function relies on efficient cerebral blood flow (CBF) to wash away harmful waste products for disposal and supply the brain with an adequate supply of oxygen and sufficient nutrients.

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Apr 29, 2019

An Interview with Jose Cordeiro

Posted by in categories: bioengineering, biotech/medical, economics, finance, life extension, lifeboat, space

Jose Cordeiro is promoting the development of rejuvenation biotechnologies in Spain and the integration of Latin American immigrants into Spain’s aging society to maintain the country’s productivity. He was at the recent Undoing aging conference in Berlin and gave us an interview about his political goals.


At Undoing Aging 2019, jointly organized by SENS Research Foundation and Forever Healthy Foundation, there was a session focused on the ways to make healthy life extension and medical progress a greater part of the global agenda. Among the speakers there was Jose Cordeiro, the vice chair of Humanity Plus, director of The Millennium Project, fellow of the World Academy of Art and Science, and board member of the Lifeboat Foundation.

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Apr 28, 2019

Combating Osteoarthritis With Stem Cells

Posted by in categories: biotech/medical, life extension

An estimated 30 million Americans are affected by osteoarthritis according to the CDC, and it is predominantly a disease of older age affecting more than 1 in 10 people aged 60+; with the aging population this number is likely to continue to rise steadily.

When cartilage naturally cushioning joints breaks down, osteoarthritis of the knee occurs, without this buffer bones can come into contact with each other causing pain, stiffness, and loss of flexibility.

Medications and physical interventions can ease symptoms of osteoarthritis, but currently there is no sure as it is not possible to regrow cartilage, once progressed to end stages the only option is surgical replacement of the joint. Stem cells were recently used to ease osteoarthritis in a small scale preliminary trial with promising results that will pave the way for more larger studies.

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Apr 28, 2019

Human dental pulp stem cells: Applications in future regenerative medicine

Posted by in categories: biotech/medical, life extension, neuroscience

Stem cells are pluripotent cells, having a property of differentiating into various types of cells of human body. Several studies have developed mesenchymal stem cells (MSCs) from various human tissues, peripheral blood and body fluids. These cells are then characterized by cellular and molecular markers to understand their specific phenotypes. Dental pulp stem cells (DPSCs) are having a MSCs phenotype and they are differentiated into neuron, cardiomyocytes, chondrocytes, osteoblasts, liver cells and β cells of islet of pancreas. Thus, DPSCs have shown great potentiality to use in regenerative medicine for treatment of various human diseases including dental related problems. These cells can also be developed into induced pluripotent stem cells by incorporation of pluripotency markers and use for regenerative therapies of various diseases. The DPSCs are derived from various dental tissues such as human exfoliated deciduous teeth, apical papilla, periodontal ligament and dental follicle tissue. This review will overview the information about isolation, cellular and molecular characterization and differentiation of DPSCs into various types of human cells and thus these cells have important applications in regenerative therapies for various diseases. This review will be most useful for postgraduate dental students as well as scientists working in the field of oral pathology and oral medicine.

Keywords: Human dental pulp stem cells, Mesenchymal stem cells, Dentin, Pluripotency, Stem cell therapy, Molecular markers.

Core tip: Human dental pulp stem cells (DPSCs) have shown a potentiality for the treatment of various human diseases including dental related problems. The review will overview the information about DPSCs, their isolation, cellular and molecular characterization, differentiation into various types of cells and their applications in regenerative therapies for various diseases. This review will be most useful for postgraduate dental students as well as the scientists working in the field of oral pathology, oral medicine and regenerative medicine.

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