Lifeboat Foundation

(Part of the look back at the best of 2017)

Summary: Doctors lengthen telomeres with RNA therapy to reverse aging in human cells, according to a new research report. Telomere attrition is one of the nine hallmarks of aging. [Author: Brady Hartman] This article first appeared on LongevityFacts.]

Dr. John Cooke is department chair of cardiovascular sciences at Houston Methodist Research Institute and is the lead author of a recent paper published in the Journal of the American College of Cardiology. Dr. Cooke’s team used RNA therapy to lengthen the telomeres of patients’ cells, making them younger in the process. In a video statement accompanying the report, the lead author remarked:

Continue reading “New RNA Telomere Therapy Reverses Aging” »

“Yes, Mr. Bedford is here.”

That’s what Marji Klima, executive assistant at the Alcor Life Extension Foundation in Scottsdale, Arizona, told me over email this week. She was referring to Dr. James Hiram Bedford, a former University of California-Berkeley psychology professor who died of renal cancer on Jan. 12, 1967. Bedford was the first human to be cryonically preserved—that is, frozen and stored indefinitely in the hopes that technology to revive him will one day exist. He’s been at Alcor since 1991.

His was the first of 300 bodies and brains currently preserved in the world’s three known commercial cryonics facilities: Alcor; the Cryonics Institute in Clinton Township, Michigan; and KrioRus near Moscow. Another 3,000 people still living have arranged to join them upon what cryonicists call “deanimation.” In other words, death.

Continue reading “Fifty years frozen: The world’s first cryonically preserved human’s disturbing journey to immortality” »

Macromolecular damage contributes to the chronic diseases of aging. Geroscientists hope to repair the damage by inducing autophagy.

Looking back at best of 2017)

A clinical trial of rapamycin on healthy seniors. The anti-aging drug extends the lifespan of mice and reduces inflammation markers.

Looking back at best of 2017)

The finding was a milestone in the field of anti-aging science. Professor Judith Campisi, Ph.D., a celebrity in the anti-aging field, and lead author of the study remarked

“Imagine the possibility of taking a pill [rapamycin] for a few days or weeks every few years, as opposed to taking something with side effects every day for the rest of your life. It’s a new way of looking at how we could deal with age-related maladies.” – Judith Campisi, PhD

Continue reading “Can We Slow Aging in our Bodies with Intermittent Rapamycin Therapy?” »

Looking back at best of 2017)

Summary: Nanotechnology meets gene editing. MIT researchers use nanoparticles instead of viruses to deliver the CRISPR gene editing system. This article first appeared on LongevityFacts. Author: Brady Hartman]

In a new study, MIT scientists have developed nanoparticles that deliver the CRISPR gene editing system, eliminating the need to use viruses for delivery.

Continue reading “Revolutionary CRISPR Gene Editing with Nanoparticles” »

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SENS Research Foundation is a 501©(3) public charity that is transforming the way the world researches and treats age-related disease.

Continue reading “Aubrey de Grey” »

Treating the diseases of ageing requires rethinking of our approach to treating disease. Rather than a “whack-a-mole” strategy going after individual conditions, a concerted medical effort against ageing as a whole is in order.

Aging is something that we all share, rich or poor; it is something that happens to us all, and we are taught from a young age that it is inevitable. However, some scientists believe that aging is amenable to medical intervention and that such interventions could be the solution to preventing or reversing age-related diseases.

Academics are currently debating whether aging is natural or a pathological disease that we can treat.

Continue reading “Is aging natural or a pathological disease that we can treat?” »

An interview with Drs. Irina and Michael Conboy on the topic of young blood and blood filtering for rejuvenation purposes.

Due to a recently published study on the effects of young plasma on aged mice, we got in touch with Dr. Irina Conboy of Berkeley University. Dr. Conboy is an Associate Professor at the Department of Bioengineering and an expert in stem cell niche engineering, tissue repair, stem cell aging and rejuvenation. Before we dive into the main topic, let’s familiarize ourselves a little with Dr. Conboy and her work.

Dr. Conboy got her Ph.D. at Stanford University, focusing on autoimmunity. She met her partner in science—and in life—Dr. Michael Conboy at Harvard and they got married before embarking on graduate studies; they celebrated their Silver Anniversary a few years ago. During her postdoctoral studies, she began focusing on muscle stem cells, trying to figure out what directs them to make new healthy tissue and what causes them to lose their ability to regenerate the tissues they reside in as we age[1].

Continue reading “Could Filtering Our Aged Blood Keep us Young?” »