Lifeboat Foundation

As humans, we are defined by, among other things, our desire to transcend our humanity. Mythology, religion, fiction and science offer different versions of this dream. Transhumanism – a social movement predicated on the belief that we can and should leave behind our biological condition by merging with technology – is a kind of feverish amalgamation of all four. Though it’s oriented toward the future, and is fuelled by excitable speculation about the implications of the latest science and technology, its roots can be glimpsed in ancient stories like that of the Sumerian king Gilgamesh and his quest for immortality.

Will humans ever conquer mortality by merging with technology? The 2018 Wellcome prize winner shares his favourite books on transhumanism, from a cyborg manifesto to a Don DeLillo novel.

Mark O’Connell

Continue reading “Mark O’Connell: five books to understand transhumanism” »

This week RT en Español aired a half hour show on life extension and #transhumanism on TV to millions of its #Spanish viewers. My #ImmortalityBus and work was covered. Various Lifeboat Foundation members in this video: Give it a watch:

La longevidad, la inmortalidad… Temas que nunca han dejado a nadie indiferente. Ahora algunos científicos aseguran que la inmortalidad es técnicamente alcanzable en un futuro cercano. Pero al mismo tiempo surgen preguntas de carácter moral e incluso filosófico: ¿qué significa alcanzar la inmortalidad para cada uno de nosotros? Además, en una sociedad consumista y de empresas transnacionales como la nuestra, suena poco convincente que la inmortalidad pueda llegar a ser accesible para todos.

Continue reading “La conquista de la muerte” »

A discussion on whether or not extended lifespans might make us paranoid about every tiniest risk.

Some months back, I read “Sapiens: A Brief History of Humankind” by Yuval Noah Harari. It’s a really good book, though it did disappoint me significantly when, after discussing the past and the present of our species, the author began glancing towards possible futures. At that point, the impartiality required of a historian, which Harari had thus far managed to keep up more or less evenly throughout the book, gave way to a subtly implied pessimism pervading, among other things, his views on future rejuvenation biotechnology.

Honestly, I wasn’t expecting him to even touch upon the subject; I was pleasantly surprised, at least until I realized that his concerns, most of which were the usual ones you’d expect, seemed to make him inclined to see rejuvenation as a plague rather than a blessing.

Continue reading “On life extension and risk aversion” »

Fasting has been found to have a range of health benefits, and appears to slow down the aging process. Now, researchers from MIT have found that fasting for just 24 hours is enough to improve the regeneration of a person’s intestinal stem cells, which naturally declines with age. Better yet, with the metabolic switch identified, in the future the effect could be mimicked with a drug.

As with stem cells in all parts of the body, intestinal stem cells are in charge of growing new cells in the organ. They maintain the lining of the intestine, which is shed and replaced every few days, fight off infection and repair damage to the tissue. But as is usually the case, these stem cells get less and less effective at their job with age.

Previous research has found that caloric restriction, or continual fasting, has a profound effect on health and longevity. These effects have been seen in mice, rats, monkeys, lemurs, and other animals, and although human studies haven’t really been conducted, it seems that we could also benefit from harnessing the diet. So the MIT team set out to study the effects of fasting on intestinal stem cells.

Biologist George Church says the idea is to live to 130 in the body of a 22-year-old.

Today we take an amusing look at how science fiction is often portrayed in a jarring way especially when dealing with the topic of life extension.

Those of us who fancy science fiction stories are used to all sorts of technological miracles taking place in them; some are plausible and might become reality at some point in the future, while others are mere fantasies, artistic liberties that are taken to tell a better story and will likely never translate into real-life technologies—or, if they will, they will do so at the cost of rethinking fundamental principles that we’ve thus far considered to be fully established.

In science fiction, we’ve seen faster-than-light travel, teleportation, portals, energy weapons, strong AI, telepathic powers, and radiation-induced superpowers of all kinds; unfortunately, the only “superpower” known to be actually induced by radiation thus far is cancer. Entire imaginary worlds have revolved around the existence of one or more of these marvels, and series and shows have assumed that they’re possible and imagined what our society would be like with them, but one particular possibility has been neglected or relegated to one or two episodes and then forgotten, as if it was of no importance whatsoever: the defeat of aging.

Continue reading “Life Extension Technology in Science Fiction” »

Today, we have an interview with the Longevity Research Institute, a new group set to launch in April 2018 of this year. The goal of the Institute is to identify therapies that can demonstrably extend healthy human lifespan by 2030 at the latest.

Searching for longevity

There are dozens of compounds and therapies that have been demonstrated to increase the lifespan of mammals. Recently, there have been some impressive examples of rejuvenation in animals using a variety of approaches, including partial cellular reprogramming, stem cell therapy, and senescent cell removal. More importantly, in many of these studies, age-related diseases have been delayed or even reversed.

Continue reading “Dr. Sarah Constantin – The Longevity Research Institute” »

Here is how we could reverse aging.