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Category: life extension – Page 467

1st Age Reversal Results—Is it HGH or Something Else?

Yesterday, the TRIIM study was described in science news headlines around the world, though, through a glitch, the original research paper is not yet on the Aging Cell web site. (You saw it first here.) I refer you to the writeup in Nature’s News section for a full summary of the paper, and in this column I will add my personal framing, and what I know about the study from private connection to its authors and one of the subjects. The big news is setback of the epigenetic clock, by several methylation measures. Instead of getting a year older during the trial, nine subjects got a year younger, on average, based on the version of the Horvath methylation clock that best predicts lifespan. The study had been originally designed to regrow the thymus. (Loss of thymus function has been linked to the collapse of the immune system that occurs typically before age 70.) Imaging showed that the functional part of the thymus expanded over the course of the trial, and blood tests confirmed improved immune function. The treatment included.

Longevity: A Radical New Science

Getting old is an unavoidable truth of life. And yet, for most of modern history this mortal coil has baffled scientists. Over the past decade, however, researchers have made great strides in understanding the cellular, molecular, and genetic tableau of aging—which has brought the next question into sharp focus: Can aging be stopped? While a full answer remains elusive, recent advancements have opened the door for significantly extending the human lifespan. One controversial researcher even claims that the first person who will live 1,000 years has already been born. Mainstream researchers are decidedly more cautious in their predictions, but the prospect of postponing mortality, even in modest ways, raises important ethical, social, and practical questions. How would we control an increasingly out-of-control global population? Does life have meaning without death? Even if we could live forever, would we want to?

The World Science Festival gathers great minds in science and the arts to produce live and digital content that allows a broad general audience to engage with scientific discoveries. Our mission is to cultivate a general public informed by science, inspired by its wonder, convinced of its value, and prepared to engage with its implications for the future.

Visit our Website: http://www.worldsciencefestival.com/
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Original Program Date: June 2, 2011
MODERATOR: Bill Ritter
PARTICIPANTS: Leonard Guarente, Judith Campisi, Michael Rose, Aubrey de Grey.

Bill Ritter’s Introduction 0:05

Does Life Have Meaning Without Death? 02:50.

Continue reading “Longevity: A Radical New Science” | >

James Strole: Advocacy, Education, Awareness About Radical Life Extension

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews James Strole, Co-Founder and Co-Director of People Unlimited and Director of the Coalition For Radical Life Extension.

Ira Pastor Comments:

On the last several shows we have spent time on different hierarchical levels the biologic-architecture of the life, disease and aging process. We’ve spent some time talking about the genome, the microbiome, tissue engineering, systems biology, quantum biology, organism hydrodynamics, biosemiotics, and chronobiology.

As exciting and promising as all of these research paths are, at the end of the day, in order for them to yield what many of us are looking for, radically extended healthspans and lifespans, and for them to be translated at scale, that is: approved by regulators, marketed by large pharma and CPG companies, and prescribed by a millions of clinicians (especially as the target market is all 7+ billion inhabitants of the planet), there needs to be an appropriate system of advocacy, education, awareness, and networking built around them to spread the word of the possibilities and the beautiful future that they can bring.

For today’s guest, I could think of no one better to come talk with us about this topic and take us into the future, than James Strole.

James is the Co-Founder and Co-Director of People Unlimited, an organization that’s involved in inspiring, educating, and connecting like minded people interested in achieving unlimited lifespans.

Continue reading “James Strole: Advocacy, Education, Awareness About Radical Life Extension” | >

Study Results Suggest Human Aging Can Be Reversed

A small clinical trial, which was conducted by a team of researchers led by Dr. Greg Fahy, has shown for the first time in humans that reversing biological age may be possible.

The results of TRIIM are in

The researchers spent a year running the Thymus Regeneration, Immunorestoration, and Insulin Mitigation (TRIIM) trial, which included 9 volunteers aged between 51 and 65. The trial was aimed at testing if a growth hormone and drug combination could be used safely in humans to restore thymic function lost due to aging [1].

James Strole — Director of the Coalition for Radical Life Extension / Producer of RAADfest — ideaXme Show — Ira Pastor

World’s first anti-aging trial gets green-light

A 5 year study. In recent years it has been shown to extend the lives of nematodes (or roundworms) by 57% and mice by 6%. In humans, claims abound that metformin-takers are living longer, having fewer cardiovascular episodes and seeing reduced odds of getting cancer.

Groundbreaking TAME trial, which directly targets aging as an endpoint, finally begins this November, reveals lead clinician Dr Nir Barzilai.

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