Lifeboat Foundation

Why is it so hard to convince people living longer is a good thing? This short article has some evidence worth considering.

Most advocates of life extension report facing resistance to the idea of increased lifespans by medical means when trying to disseminate this idea among general public. Resistance manifests itself in many forms, ranging from concerns such as overpopulation to concerns about unequal access to life extending treatments. But the most unexpected thing is probably that people often don’t want an increased lifespan at all. Surveys in different countries show, that when people are asked “how long would you like to live?”, they often give a number equal to or slightly higher than the current life expectancy in a given country[1–4].

But wait… Isn’t extending life for more decades a good thing that everyone should strive for? In reality we often do not see enough enthusiasm for the idea in general. So why is this?

Continue reading “Intrinsic resistance to the idea of life extension or wrong messaging?” »

Microbial burden is a real problem in aging and researchers are finding ways to boost our immune system to resist these microscopic enemies.

Microbial burden is a significant contribution to aging and our bodies are under daily attack from these microscopic invaders. The more completely we can remove these invaders the less impact they will have on the aging process.

“Researchers at the University of Illinois at Urbana-Champaign and Newcastle University in the U.K. are investigating how infectious microbes can survive attacks by the body’s immune system. By better understanding the bacteria’s defenses, new strategies can be developed to cure infections that are currently resistant to treatments, the researchers said”

Continue reading “Team discovers how bacteria exploit a chink in the body’s armor” »

“His body, along with the others, will remain frozen indefinitely, with enough ongoing financial support to sustain its current state, news.com.au reported.

Last year, a Massachusetts Institute of Technology graduate successfully froze and reanimated a rabbit brain”.

Since his death, James Bedford’s body has been cryogenically frozen and awaiting reanimation on the edge of the Sonaran Desert in Arizona. This week marks the 50th year of Bedford’s deep freeze, making him the oldest “de-animated” human being on earth.

Continue reading “After 50 years, frozen WWI veteran’s body awaits reanimation” »

A quick look at synthetic biology and its potential for health and treating age-related diseases.

All living organisms contain an instruction set that determines what they look like and what they do. These instructions are encoded in the organism’s DNA within every cell, this is an organism’s genetic code (or “genome”).

Mankind has been altering the genetic code of plants and animals for thousands of years, by selectively breeding individuals with desired features. Over time we have become experts at viewing and manipulating this code, and we can now take genetic information associated with the desired features from one organism, and add it into another one. This is the basis of genetic engineering, which has allowed us to speed up the process of developing new breeds of plants and animals.

Continue reading “Will synthetic biology help us to eliminate age-related diseases?” »

Some exciting news from Lifespan.io about their current senescent cell therapy campaign.

While the CellAge campaign has done a great job thus far, with over 200 backers raising $11,000+ to better target dysfunctional “senescent” cells in the body, many supporters have let us know that the holidays, along with other concurrent fundraisers, have made it challenging to contribute.

In response we have decided to announce a 1-month extension for the CellAge campaign, and give the generous members of our community greater opportunity to support this important research.

Continue reading “CellAge 1-month campaign extension announced” »

It seems more likely what you remove is more important than what you add with old blood.

The evidence is increasingly suggesting that dilution of pro-aging signals is why we are seeing rejuvenation when blood is exchanged between young and old animals. Forget transfusions the next step is to filter our own blood to promote health as we age.

#aging #crowdfundthecure

Continue reading “Forget blood transfusions, the fountain of youth could be closer to hand” »

We are at the cusp of a stem cell revolution.

Understanding and harnessing these unique cells may unlock breakthroughs in longevity and therapeutic solutions to all kinds of chronic diseases and regenerative opportunities.

Last month, I took a trip down to the Stem Cell Institute in Panama City with Dr. Bob Hariri (co-Founder of Human Longevity Inc.) to get stem cell injections in my knee and shoulder as an alternative to reconstructive surgery.

Continue reading “Stem Cells Are Poised to Change Health and Medicine Forever” »

Exercise is one of the best ways to slow down aging and its free too!

(Boston) — Older adults who experience good cardiac fitness may be also keeping their brains in good shape as well.

In what is believed to be the first study of its kind, older adults who scored high on cardiorespiratory fitness (CRF) tests performed better on memory tasks than those who had low CRF. Further, the more fit older adults were, the more active their brain was during learning. These findings appear in the journal Cortex. Difficulty remembering new information represents one of the most common complaints in aging and decreased memory performance is one of the hallmark impairments in Alzheimer’s disease.

Continue reading “Older, fitter adults experience greater brain activity while learning” »

(Phys.org) —Tufts University biologists using new, automated training and testing techniques have found that planarian flatworms store memory outside their brains and, if their heads are removed, can apparently imprint these memories on their new brains during regeneration.

The work, published online in the Journal of Experimental Biology, can help unlock the secrets of how memories can be encoded in living tissues, noted Michael Levin, Ph.D., Vannevar Bush professor of biology at Tufts and senior author on the paper.

“As bioengineering and biomedicine advance, there’s a great need to better understand the dynamics of memory and the brain-body interface. For example, what will happen to stored memory if we replace big portions of aging brains with the progeny of fresh stem cells?” said Levin, who directs the Center for Regenerative and Developmental Biology in Tufts’ School of Arts and Sciences.