Lifeboat Foundation

Results of NR and pterostilbene clinical trial are promising.

A clinical trial of an NR and pterostilbene anti-aging supplement appeared to be safe over the short-term as it increased NAD levels in a sustained way. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

A clinical trial of NR and pterostilbene sustainably increased NAD levels and appeared to be safe over the short-term. Moreover, the study suggests that it increased the mobility of the aging test subjects.

Continue reading “Researchers report promising pterostilbene and NR clinical trial results” »

Could a protein called klotho block aging and dementia?

Summary: More klotho means better cognitive function says a scientist. By injecting the protein Klotho into mice with Alzheimer’s, a UCSF researcher improved their brain function. The researcher hopes to eventually apply the treatment to humans to treat aging and dementia. [Introduction by Brady Hartman, followed by a link to the full article.]

Neurologist and neuroscientist Dr. Dena Dubal wants to prevent dementia and aging with a protein called Klotho. Dr. Dubal, MD, Ph.D. – an associate professor of neurology at UC San Francisco – aims to use this novel approach to battle neurodegenerative diseases like Alzheimer’s disease and dementia.

Continue reading “Could a protein named klotho block aging and dementia?” »

Researchers solved a problem that has been holding back the use of viral vectors for cancer therapy. They re-engineered viruses with a novel stealth technique that enables them to be used to treat cancer.

Up until now, viral vectors couldn’t be used widely in cancer therapy. Researchers just announced that they re-engineered an adenovirus with a novel stealth technique that enables it to be used to fight tumors. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

Viral vectors are well-developed tools used by scientists to deliver genetic material into cells. Unfortunately, they haven’t worked well to treat cancer until a group of researchers in Switzerland re-engineered them to enable them to be used in cancer therapy.

Continue reading “Revolutionary stealth virus holds promise for cancer therapy” »

When developing any personal health and longevity strategy it is essential to apply the scientific method.

There is one common public reaction to my talks that bothers me quite a bit. I am worried that after each of my lectures, people will just start taking lots of anti-aging pills without regard for dosage or effectiveness, potentially hurting themselves in the process.

This is because one of the most common reactions to me mentioning any currently available interventions is to search for each and every component and order them all right away. Whatever I say about safety and the need to test before people make any changes in their lifestyles seems ineffective.

Continue reading “Developing a Science-based Personal Longevity Strategy” »

Idiopathic pulmonary fibrosis is a disease associated with critically short telomeres, and it currently lacks a reliable and effective treatment. Researchers at the Telomere and Telomerase Group at the Spanish National Cancer Research Centre (CNIO) have cured the disease in mice using telomerase therapy to lengthen short telomeres.

A proof of concept for an effective treatment against pulmonary fibrosis

The authors of this study have stated that this is a “proof of concept that telomerase activation represents an effective treatment against pulmonary fibrosis” in their publication[1].

Part #1 of an awesome show with Steve and Jason on Grognostics merging together discussions on biotech, craft beer, human potential, as well as a comedic journey into the world of 2039

https://www.stitcher.com/podcast/grognostics/e/53077743?autoplay=true

This revolutionary gene modified T cell therapy is bearing fruit in treating a type of lymphoma, a resistant form of cancer.

Summary: After years of effort, this revolutionary gene-modified T cell therapy is bearing fruit in treating a type of lymphoma, a resistant form of cancer. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

Thirty-seven-year-old Nick Asoian of Denver unsuccessfully fought Hodgkin’s Lymphoma using conventional cancer treatments for two years. In 2008, while in New Zealand for a ski race, Nick was diagnosed with Hodgkin’s Lymphoma. Two bone marrow transplants and two years of chemotherapy combined with radiation therapy didn’t bring his cancer to heel.

Continue reading “Revolutionary gene edited T cell therapy to treat lymphoma shows promise and little toxicity” »

Einstein’s secret to an incredibly intelligent brain may be in part to how well his brain aged…

Samples of his brain revealed he was missing a protein Lipofuscin, a not so well understood compound which contains lipid residues of lysosomal digestion that accumulates in the brain liver kidney, heart muscle, retina, adrenals, nerve cells, and ganglion cells.

Lipofuscin busting drugs could have a lot of potential for anti-aging therapies for the future.

The debate over telomeres length is now back in the spotlight… Here is a brief review of the top articles on telomere length, telomerase and human diseases such as cancer…

A review of the top articles on telomerase and telomere length which play a role in the chronic diseases of aging, such as cancer.