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Steve Hill from the LEAF team gives some first impressions from the recent Undoing Aging 2018 conference in Berlin.


I have just returned home from the Undoing Aging conference in Berlin, where we spent three days listening to talks by the top researchers in aging, meeting some of the finest minds in research, and talking with thought leaders in the field.

There was a great deal of new and exciting research being presented, some of which has not been published and so cannot be discussed. We will be publishing articles on this news in the coming days as we edit the audio and video from the event. Today, however, instead of discussing research per se, I’ll talk about my impressions of the event.

This was my first conference on aging, and I have to say that I was really impressed with the professional presentation and venue. I have been to many video game conferences in my life, and I have to say it was on par with such events, albeit on a somewhat smaller scale.

March 19 (UPI) — Researchers in California have developed a retinal patch with stem cells to improve the vision of people with age-related macular degeneration.

In a clinical trial, researchers at the University of California Santa Barbara implanted the stem cell-derived ocular cells in two patients over the course of 12 months, publishing the results of the study Monday in the journal in Nature Biotechnology.

Macular degeneration, which affects the central, or reading, vision while leaving the surrounding vision normal, usually affects people over 50 years of age. The Centers for Disease Control and Prevention estimates that 1.8 million Americans aged 40 years and older have AMD, and it’s the leading cause of permanent impairment of close-up vision among people aged 65 years and older.

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Summary: Scientists just discovered bacteria that trigger autoimmune conditions and found that a simple antibiotic or vaccination stopped the autoimmune reaction. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

Yale University researchers discovered a strain of gut bacteria that can travel throughout the body and trigger an autoimmune reaction. More importantly, the scientists say that administering simple antibiotics or vaccines can suppress the autoimmune response, and hold promise as new treatments for chronic autoimmune conditions, such as autoimmune liver disease and systemic lupus.

An autoimmune disease is a condition in which the immune system mistakenly attacks healthy tissue. Up until the new study, scientists weren’t sure what causes autoimmune disease. However, researchers have long suspected that bacteria and viruses play a role.

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Summary: Cholesterol drug alirocumab was linked to a 15% lower risk of dying in a new study released Saturday. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

The cholesterol-lowering drug alirocumab was linked to a 15% lower risk of death, and an equivalent reduction of cardiovascular events, such as heart attack and stroke, according to a new study.

It’s the first time a cholesterol-lowering drug has reduced deaths since statins such as Crestor and Lipitor came out decades ago.

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Summary: Vitamin D linked to a 20% lower risk of cancer in an extensive 16-year study of over 33,000 people published yesterday in a top journal. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

Higher levels of vitamin D may be connected to a lower risk of developing cancer, concludes an extensive study of Japanese adults published yesterday.

The scientists say their findings support the theory that vitamin D might help protect against some cancers.

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Summary: A sneak peek of an upcoming documentary takes us inside the minds of the leaders in the life extension field and their recent discoveries to ward off the diseases of aging. [This article has been updated and first appeared on LongevityFacts. Author: Brady Hartman.]

Leaders in the field of longevity research plan to help us live healthier, longer lives with their recent scientific discoveries.

Sixteen of the leading scientists in the field of life extension, called geroscientists, are showcased in a new PBS documentary called “Incredible Aging: Adding Life to Your Years.”

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Summary: In a medical first, UT Dallas researchers just found a way to paint a bullseye target on cancer stem cells, the source of tumor metastases which spread through the body to cause 90% of all cancer deaths. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

Researchers with the University of Texas at Dallas just found a way to isolate and tag cancer stem cells, the chief culprit involved in cancer spreading to other parts of the body – the cause of 90% of all cancer deaths.

While they haven’t developed drugs that eliminate these aggressive cancer cells, they can paint a bright bullseye on their elusive target, making it easier to kill cancer stem cells.

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Utilizing induced pluripotent stem cells for regenerative medicine.


The #heart is the first organ to develop in the womb and the first cause of concern for many parents.

For expecting mothers, the excitement of pregnancy is often offset by anxiety over medication they require. Parents and doctors often have to consider the mother’s health as well as the potential risk regarding how medication could affect their baby. The U.S. Food and Drug Administration requires certain drugs to be labeled with pregnancy exposure and risk. Some drugs are labeled to show that testing on animals has failed to demonstrate a risk but there are no adequate and well-controlled studies of pregnant women.

“Some drugs are difficult for doctors to prescribe to pregnant women because they don’t know the embryo toxicity, how does that effect fetal development,” said biomedical engineering Professor Zhen Ma. “They don’t have the clinical outcome based on human study.”