Lifeboat Foundation

More data for caloric restriction and health benefits.

The long-term response to calorie restriction has long been of interest to the aging research community, and particularly in the past few decades as the tools of biotechnology allowed for a more detailed analysis of the metabolic changes that accompany a reduced calorie intake. A restricted diet extends healthy life spans in near all species tested to date, though to a much greater extent in short-lived species than in long-lived species such as our own. Considerable effort is presently devoted to the development of drugs that can replicate some fraction of calorie restriction — more effort than is merited in my opinion, given that the optimal result for extension of human life span achieved via calorie restriction mimetics will be both hard to achieve safely and very limited in comparison to the gains possible through rejuvenation therapies after the SENS model. Repairing damage within the existing system should be expected to outdo attempts to change the system in order to slow the accumulation of damage, in both efficiency and size of result.

Not everyone is interested in the long term, however. The short term health benefits of calorie restriction appear quickly and are surprisingly similar in mice and humans, given that calorie restriction in mice results in significantly extended life and calorie restriction in humans does not. The beneficial adjustments to metabolism and organ function are for the most part larger and more reliable than similar gains presently achievable through forms of medicine. That is more a case of medical science having a long way to go yet than calorie restriction being wondrous, however. Still, the short term benefits are coming to the attention to wider audience within the research and medical community.

Continue reading “Calorie Restriction as a Means to Improve Surgical Outcomes” »

Grassroots funding of fundamental science and private enterprize will lead the way in rejuvenation biotechnology not the traditional funding sources from Government which are shrinking every year.

It is important to understand that innovation and progress is unlikely to come from the Government and the traditional grant system which is shrinking every year. Rejuvenation biotechnology will likely be funded with a mix of fundraising for fundamental breakthrough technologies followed by private enterprize taking discoveries to market. This is why supporting science is critcial as relying on the Government to innovate and drive progress is unlikely to yield results anytime soon.

“Today, researchers compete for government grants at increasingly shorter intervals and with diminishing chances of success: Less than 1 in 5 grant applications succeeds. This inhibits risk taking.

Continue reading “Don’t Thank Big Government for Medical Breakthroughs” »

https://www.youtube.com/watch?v=N8D327VqFfw

Heck of a cheerleader. First Amendment Aspirin?

It’s an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, and improve organ function. This strategy may bring us one step closer to the “fountain of youth,” but it’s important to be cautious and not hype, says researcher of aging Peter de Keizer of the Erasmus University Medical Center in the Netherlands. In an Opinion published December 29 in Trends in Molecule Medicine, he discusses the milestones the field still needs to hit before translation in humans is ready for discussion.

#aging #crowdfundthecure

https://www.sciencedaily.com/releases/2016/12/161229141835.htm

Continue reading “Anti-aging therapies targeting senescent cells: Facts and fiction” »

121 people including me have already sent their gifts to CellAge project, what about you? wink

Hello everyone! There are some great news, today CellAge campaign successfully reached amazing $6 000! This makes 15% of the goal, and we are very grateful to 121 brave people who decided to support the development of a universal test system to target senescent cells!

If you have not yet supported the campaign with a donation, here is a reminder that the best New Year gift for scientists is funding to launch another longevity study! bigsmile

Continue reading “The best gift scientists can have for the New Year is funding for another longevity research!” »

My grandparents taught me the importance of a power nap; and it does help.

We’re not sure what the boss would have to say about it if you suddenly downed tools and made a decision to have a little sleep, but new research has found that taking an hour’s nap after lunch can have a number of health benefits, including preventing brain ageing.

The study conducted among the older Chinese men by a team of worldwide researchers concentrated mainly on post-lunchtime napping and its impact on the health of elderly people.

Continue reading “Hour-Long Nap May Boost Brain Function in Older Adults” »

The most recent Bill Andrews vid I know of.

Dr. Ed Park of Recharge Biomedical interviews telomere scientist, Dr. Bill Andrews at the 2016 AMMG conference.

Continue reading “Bill Andrews on why telomerase doesn’t cause cancer” »

Dr. James Kirkland talks about senescent cell removal and even more human clinical trials heading our way in the near future.

Dr James Kirkland on how senescent cell removal increases healthspan and how they contribute to age-related diseases like heart disease, cancer, diabetes and more.

Continue reading “Cellular Senescence and Fundamental Aging Processes” »

https://www.youtube.com/watch?v=DealmN94tRw

Stem Cell therapy, is one form of Comprehensive Prolotherapy available for arthritis treatment, and other chronic pain conditions at Caring Medical and Rehabilitation Services. Our same-day procedure utilizes a person’s own mesenchymal stem cells from bone marrow or fat cells to treat degenerated joints. In this video, the stem cell therapy treatment is demonstrated on an athlete with severe osteoarthritis of the knee, by Ross Hauser, MD. Dr. Hauser has specialized in comprehensive Prolotherapy and Orthobiologic treatments since 1993 and treated tens of thousands of patients with excellent success, even patients who have failed surgery, knee replacement, or other treatments for arthritis and pain. To make an appointment with one of our specialists or for an opinion on your case and to learn more about our Stem Cell Prolotherapy, visit us at http://www.caringmedical.com/stem-cell-therapy/

Contact our team to tell us more about your case and see if you are a good candidate for our treatments:

Continue reading “Stem Cell Therapy Injections” »