Toggle light / dark theme

End Aging Now

As we age, the thymus begins to shrink, and fewer numbers of T cells are created and trained to fight. This structural decay of the thymus is one of the main reasons why we become increasingly vulnerable to infectious diseases, such as influenza and pneumonia. The other reason is immune cells becoming senescent.

So, what can we do about it? Check out our new exclusive interview and find out.

Dr. Greg Fahy – Rejuvenating the Thymus to Prevent Age-related Diseases

As we age, the thymus begins to shrink, and fewer numbers of T cells are created and trained to fight. This structural decay of the thymus is one of the main reasons why we become increasingly vulnerable to infectious diseases, such as influenza and pneumonia. The other reason is immune cells becoming senescent.

There are a number of possible solutions to this problem. Firstly, engineering new healthy and youthful thymic tissue might help to restore the immune system, and indeed a number of groups are working towards this.

Secondly, some researchers are focused on encouraging the aged thymus to regrow using various approaches, such as stem cell transplants, cellular reprogramming or chemical compounds. Dr. Greg Fahy is involved in researching this second approach, and we had the opportunity to speak to him about this work.

Jim Mellon talks to Dominic Frisby in Stuff That Interests Me

For this new book, Jim and Al have spent a year sifting through the cutting-edge research, visiting laboratories and interviewing key opinion leaders in the field of life extension. https://www.juvenescence-book.com/


My guest today on Stuff That Interests Me is one of Britain’s most successful investors, Jim Mellon.

You’re going to live till your 120.

Jim explains why — a combination of new drugs, technologies and lifestyles. What are you going to do with all your time?

The next great investment trend will be around the fact that we are all going to love a lot longer. Find out more in the this fascinating interview.

Removing Senescent Cells with Senolytics Could Help us Live Healthier and Longer Lives

By treating one of the root causes of aging – senescent cells – a new class of drugs, known as senolytics, has the potential to treat a wide range of age-related diseases rather than the traditional approach of dealing with them one at a time.

Today we are going to take a look at what senescent cells are, how they contribute to age-related diseases and a new review by the Mayo Clinic that shows what we can do about this problem. We all age, but the research suggests that we may not have to suffer from age-related ill health.

Inktober2017: Creating Unique Artwork to Support Research

A great initiative by Laura Katrin Weston one of our amazing volunteers. She is supporting research fundraising using the wonderful artwork she produces at Black Cat Studios.

Black Cat Studios is a small private recording, music production and art studio in Leicestershire, UK, providing a range of services for musicians, broadcasters, and game developers. It is really great to see the community starting to use their talents and passions outside of longevity to help support research. All proceeds will go to Lifespan.io and we will use them to support cutting-edge medical research projects such as MouseAge.

Laura will be producing artwork based on 31 themes all with a longevity or transhumanist flavor to them based on this list:

Meet the Extensionists: People Who Believe Immortality Is Possible

Leading women’s magazine Marie Claire has a feature story on life extension out this month (approx 1.5 million circulation):


Forget about life after death. More and more, women around the country are seeking another kind of miracle: not dying at all.

What if you could hit the pause button on aging? Live to 120 without feeling a day over 80? More radical still, what if you could cheat death? Would you do it?

“Life extensionists” would. That’s the name modern immortality seekers now go by, and devotees range from those who’d like to live healthier lives into old age to the more extreme, who ardently believe that humans can, and should, overcome death the same way we’ve overcome, say, smallpox or tooth decay.

Life expectancy for women in the United States has risen steadily from 73 in the 1960s to 81 today, with those numbers continuing to increase thanks to a combination of biology and higher standards of living (not to mention the over 1,000 geneticists and biologists working in the longevity field). But life extensionists want more. They want to be cognitively and physically healthy for decades, if not centuries.

We are celebrating Longevity Month and what better way to do so than to share each other’s stories about why we care about research to end the diseases of aging

This year we want to continue this tradition by doing something special, making a video to showcase you, our community, as it is only with your outstanding help that we have been able to accomplish so much in such a short period of time.

To learn more visit our website today: https://www.leafscience.org/longevity-month-2017-tell-us-your-story/