Lifeboat Foundation

Calico, a company focused on aging research and therapeutics, today announced that Daphne Koller, Ph.D., is joining the company as Chief Computing Officer. In this newly created position, Dr. Koller will lead the company’s computational biology efforts. She will build a team focused on developing powerful computational and machine learning tools for analyzing biological and medical data sets. She and her team will work closely with the biological scientists at Calico to design experiments and construct data sets that could provide a deeper understanding into the science of longevity and support the development of new interventions to extend healthy lifespan.

Calico will try to use machine learning to understand the complex biological processes involved in aging.

Glad this discovery has been found; however, sad to hear as well. Sharing for my friends involved with anti-aging (Alex) and others work on the cancer cure.

Genetic signature of the brain cancer cell lines used for research is different from the original patient tumor cells.

I HIGHLY recommend reading this novel, as well as it sequels! It’s a beautiful, smart, and occasionally frightening exploration of what our civilization will look like post singularity, what WE will look like as posthumans, and where we might go from there.

The Golden Age is Grand Space Opera, a large-scale SF adventure novel in the tradition of A. E. Van vogt and Roger Zelazny, with perhaps a bit of Cordwainer Smith enriching the style. It is an astounding story of super science, a thrilling wonder story that recaptures the excitements of SF’s golden age writers.

The Golden Age takes place 10,000 years in the future in our solar system, an interplanetary utopian society filled with immortal humans. Within the frame of a traditional tale-the one rebel who is unhappy in utopia-Wright spins an elaborate plot web filled with suspense and passion.

Continue reading “The Golden Age” »

https://www.youtube.com/watch?v=T4U6qvNt81E&feature=youtu.be

The MMTP has recorded this film in support of SENS Research and their quest to find solutions to ALT cancer.

To support OncoSENS project with a donation click the link:

Continue reading “Elena Milova speaking in support of OncoSENS crowdfunding campaign” »

https://www.youtube.com/watch?v=5chIH_ozLkI

Inconvenient truths about aging, senescent cells and more.

Filmed August 16th 2016.

Continue reading “Aubrey de Grey and Panel — Prolonging Lifespan” »

Google’s artificial intelligence research lab DeepMind is exploring whether its technology could be used to identify early signs of eye diseases that ophthalmologists might not spot.

DeepMind, which was acquired by Google in 2014, has struck an agreement with Moorfields Eye Hospital in London that gives it access to about a million anonymous retinal scans, which it will feed into its artificial intelligence software.

Continue reading “Could an algorithm help to save people’s eyesight? Google thinks so” »

It’s an add-on for CRISPR.

Researchers have created a new genome editing technique called Target-AID, which induces point mutations instead of cutting DNA

Gene editing technology has fantastic potential, but there are remaining issues and questions over safety and specificity. The major contender is currently CRISPR-Cas9, but this induces a double stranded break in DNA which is a slightly riskier approach — particularly if it cuts in other locations too that you don’t want it to. Research teams across the world are both optimising and customising the CRISPR system; creating more accurate versions or versions that regulate gene expression as opposed to editing it. One such team has now built an add-on to CRISPR, Target-AID.

Continue reading “Safer Gene Editing Without Cleaving DNA” »

Dr Haroldo Silva from SENS talks about ALT cancer in this short film.

As normal cells divide, the ends of their chromosomes (telomeres) progressively shorten until eventually the cells reach senescence or undergo apoptosis. Cancers, which disproportionally kill more individuals in the 65 years or above age group, often overcome this built-in replication limit by expressing the enzyme telomerase.

Continue reading “Uncovering the genetic basis of ALT (Alternative Lengthening of Telomeres) — Harold Silva” »

Time people rethought outdated ideas about biology and accepted that development and aging are not one way processess and they are amenable to intervention.

Scientists have announced they can now reverse the menopause in what is thought to be a major scientific breakthrough.

Trials claim to have ‘rejuvenated’ women’s ovaries using a blood treatment normally used to help wounds heal faster and have reversed menstrual cessation in multiple women, including 40-year-old woman who underwent the menopause five years ago.

Continue reading “Menopause reversed as scientists successfully ‘rejuvenate women’s ovaries’” »