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Category: life extension – Page 598

Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You’d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.

The advertised positions are 3 month internships, with the possibility of continuing afterwards. Free accommodation will be provided for in London, alongside a negotiable salary.

The Biogerontology Research Foundation is a UK based think tank dedicated to aging research and accelerating its application worldwide.

Apply to: [email protected]

Are you an avid supporter of aging research and a keen longevity activist?

The Biogerontology Research Foundation is offering select summer internships for talented individuals. You €™d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.

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The decline of birth rate is causing a switch in society between younger workforce and the elderly. The Silver Tsunami is a real issue and one that rejuvenation biotechnology can potentially solve.

Data show productive population age group becoming smaller than the majority, and inadequate government preparation for slew of effects.

Residents of Sinpyeong township in Uiseong County, North Gyeongsang Province, were getting ready for their autumn harvest on Oct. 12. Cutting rice plants was an urgent task, they said — and all of the work is done by local village women in their seventies and older.

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Politico: Write a transhumanist in in New York! http://www.politico.com/states/new-york/albany/story/2016/10…-in-106729 #transhumanism #Election2016 #ScienceCandidate

ALBANY — While Hillary Clinton and Donald Trump have debated issues such as immigration, gun control, and health care, neither of them has weighed in on the topic of a bill of rights for cyborgs.

Voters chagrined by that oversight do, however, have another option.

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Continue reading “Worried about rights for cyborgs? There’s a write-in candidate for that” | >

I have heard many good things over the recent years on Zymergen.

Identifying high-probability, high-profit opportunities among small-cap stocks all over the world is the reason for Wall Street Daily’s existence.

That’s a big universe of companies to track.

Further complicating the project is the fact that many are cutting-edge innovators in esoteric, highly sophisticated technologies.

Continue reading “Are We on the Verge of Immortality?” | >

Bioquark Inc. (www.bioquark.com) mention on CNBC — the best way to make chemo easier is to eliminate the need for it forever!
recovering patient

Rebooting the immune system just got a bit easier. This could potentially be used to treat autoimmune diseases and just as exciting some of the aging processes.

A dietary approach to depleting blood stem cells may make it possible to conduct bone marrow transplantations without the use of chemotherapy or radiation therapy, according to researchers at the Stanford University School of Medicine.

The discovery, made in collaboration with researchers at the University of Tokyo, may also become a new way to treat certain cancers without chemo or radiation, which can cause severe side effects.

The researchers showed that a diet deficient in the essential amino acid valine could effectively deplete the population of in mice and allow them to be successfully transplanted with blood stem cells from other mice. The researchers also showed that human blood stem cells in the laboratory were affected by a lack of access to valine, suggesting that the same therapeutic approach may work in humans.

Continue reading “Withholding amino acid depletes blood stem cells, researchers say” | >

Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood.

New clues to help solve the mystery are presented in an article published in the September issue of Aging Cell by scientists at the Center for Research on Redox Processes in Biomedicine (Redoxoma), one of the Research, Innovation and Dissemination Centers (RIDCs) funded by FAPESP.

The results of in vitro and in vivo experiments performed by the Redoxoma team included the finding that a 40% reduction in dietary caloric intake increases mitochondrial calcium retention in situations where intracellular calcium levels are pathologically high. In the brain, this can help avoid the death of neurons that is associated with Alzheimer’s disease, Parkinson’s disease, epilepsy and stroke, among other neurodegenerative conditions.

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PCG-1α therapy shows promise in treating age-related decline.

It is always a good idea to look closely at the biochemistry involved in any potential Alzheimer’s disease therapy that shows promise in mouse models. There is perhaps more uncertainty for Alzheimer’s than most other age-related conditions when it comes to the degree to which the models are a useful representation of the disease state in humans — which might go some way towards explaining the promising failures that litter the field. In the research here, the authors are aiming to suppress a step in the generation of amyloid-β, one of the proteins that aggregates in growing amounts and is associated with brain cell death in Alzheimer’s disease. They achieve this goal using gene therapy to increase the level of PGC-1α, which in turn reduces the level of an enzyme involved in the production of amyloid-β. Interestingly, increased levels of PGC-1α have in the past been shown to produce modest life extension in mice, along with some of the beneficial effects to health associated with calorie restriction.

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