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Archive for the ‘life extension’ category: Page 6

Aug 16, 2024

Discovery: Human bodies begin breaking down at a very precise age

Posted by in categories: biotech/medical, genetics, life extension

It’s no revelation that the human body undergoes natural wear and tear as we age. But you might be surprised to discover that this process isn’t as gradual as we’d presumed.

A recent study reveals some remarkable truths about aging, specifically when and how our bodies start to ‘break down’

The man at the helm of the study is Michael Snyder. Chair of genetics at Stanford School of Medicine and recognized for his exceptional contribution to the field, his team’s research provides some fascinating insights into the specifics of our biological aging process.

Aug 16, 2024

Longevity Breakthrough: New Treatment Extends Lifespan and Enhances Physical Function

Posted by in categories: biotech/medical, life extension

Researchers found that removing certain inflammation-causing cells from mice every month, starting in their middle age, not only extended their lifespans but also improved their heart health and overall physical function throughout their lives. This method shows promise for extending the period of good health as mice age, potentially pointing to new aging treatments for humans.

Everyone wants to live to a ripe old age, but no one wants to be decrepit. Now, University of Connecticut researchers have demonstrated a treatment that could lengthen life—and vigor—up to the very end.

Even as human lifespans have lengthened over the past century, most people in old age suffer a serious health decline in the last decade of life. Chronic illnesses such as cancer, diabetes, or cardiovascular disease may begin, followed by frailty. Many interventions can prolong life, but not necessarily good health. And nobody wants to spend the last years of an extra-long life in decrepitude.

Aug 15, 2024

Aging dominated by two periods of rapid change, research finds

Posted by in categories: biotech/medical, life extension

Significant change can be stressful – divorce, death and moving all make the list – but when it comes to aging, a new paper identifies two flashpoints of enormous biological change. The recent study, by researchers at Stanford Medicine, uncovered evidence that human aging does not occur at a constant, gradual pace – but rather is marked by two significant bursts of molecular change. These bursts, observed in people around the ages of 44 and 60, suggest that aging may be driven by more complex biological processes than previously thought. The findings, published in Nature Aging, are based on comprehensive multi-omics profiling of 108 participants, providing a detailed look at how the human body changes during these key periods of life [1].

Longevity. Technology: The research sheds light on the nonlinear nature of aging, challenging the traditional view that aging is a steady, continuous process. By understanding why and how these bursts of aging occur, scientists may be able to uncover more about the mechanisms of aging and leverage that knowledge to improve both lifespan and healthspan. The findings also highlight the ever-evolving nature of aging research, which continues to refine our understanding of how and why we age.

The Stanford Medicine team, led by Professor Michael Snyder, PhD, analyzed a vast array of molecular data from participants aged between 25 and 75 years. Over a period spanning several years, the researchers collected blood and other biological samples from the participants, tracking more than 135,000 different molecules and microorganisms. The data set included a total of nearly 250 billion distinct data points, making this one of the most comprehensive studies of its kind [1].

Aug 15, 2024

Common drug restores youthful function to clean up aging brains

Posted by in categories: biotech/medical, life extension, neuroscience

First described by Nedergaard and her colleagues in 2012, the glymphatic system is the brain’s unique waste removal process that uses cerebrospinal fluid (CSF) to wash away excess proteins generated by energy hungry neurons and other cells in the brain during normal activity.


A drug used to induce labor in pregnant women has been shown to reactivate tiny waste-clearing pumps in the brains of old mice. The finding could hold promise as a new way to fight Alzheimer’s and Parkinson’s diseases and overall cognitive decline.

When our brains are working properly, there is an excess of proteins that build up from the energy intensive processes that take place between our neurons. Those proteins need to be removed in order for the brain to continue to operate properly. When they aren’t, they can gunk up the works, leading to the beta amyloid and tau protein tangles that are a hallmark of Alzheimer’s disease or the build up of alpha-synuclein that accompanies Parkinson’s.

Continue reading “Common drug restores youthful function to clean up aging brains” »

Aug 14, 2024

Nonlinear dynamics of multi-omics profiles during human aging

Posted by in categories: biotech/medical, life extension

Understanding the molecular changes underlying aging is important for developing biomarkers and healthy aging interventions. In this study, the authors used comprehensive multi-omics data to reveal nonlinear molecular profiles across chronological ages, highlighting two substantial variations observed around ages 40 and 60, which are linked to increased disease risks.

Aug 14, 2024

Scientists find humans age dramatically in two bursts — at 44, then 60

Posted by in category: life extension

US findings suggesting ageing is not a slow and steady process could explain spikes in health issues at certain ages.

Aug 13, 2024

Neuron-specific partial reprogramming could combat cognitive decline

Posted by in categories: biotech/medical, life extension, neuroscience

Preclinical study investigates neuron-targeted partial cellular reprogramming in the hippocampus to mitigate age-related cognitive impairments.

Aug 13, 2024

A doctor who says he’s reversed his age by 20 years eats these 7 foods every week to boost his longevity

Posted by in categories: biotech/medical, food, life extension

Completely changing your diet can be hard, so a longevity expert and doctor added foods including olive oil to his diet for the healthy aging benefits.

Aug 13, 2024

Prof. Dr. Alan Widgerow — Division Chief, Center for Tissue Engineering, UC Irvine / CSO, Galderma

Posted by in categories: bioengineering, biotech/medical, life extension

Innovation At The Frontiers Of Aesthetic And Regenerative Medicine — Prof. Dr. Alan Widgerow — Division Chief, Center for Tissue Engineering, UCIrvine — Chief Scientific Officer, Galderma.


Prof. Dr. Alan Widgerow, MBBCh, FCS, MMed, FACS, is Division Chief, Research, Center for Tissue Engineering (https://sites.uci.edu/ctelab/team/) and Adjunct Professor Plastic Surgery, Dept of Plastic Surgery, University of California, Irvine (https://faculty.uci.edu/profile/?facu…) and Chief Scientific Officer and Head of Skin Science Center of Innovation at Galderma (https://www.galderma.com/).

Continue reading “Prof. Dr. Alan Widgerow — Division Chief, Center for Tissue Engineering, UC Irvine / CSO, Galderma” »

Aug 12, 2024

3D bioprinting using stem cells

Posted by in categories: 3D printing, bioprinting, biotech/medical, life extension

Year 2018 face_with_colon_three


Pediatric Research volume 83, pages 223–231 (2018) Cite this article.

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