Modest progress at the WHO international consultation on aging.
Our parent organization the ILA has been busy and here is an article about the latest news from the World Health Organization meeting in Geneva to discuss aging research. There are some positive changes being made and well done to everyone who helped out on this project.
Was hit by a car when I was younger and broke my leg. This would have been better then a metal rod. Fascinating.
A team of researchers from the University of Michigan has developed a new technique to aid bone repair, using polymer nano-shells to deliver microRNA molecules. The method could one day have a big impact on regenerative medicine, directing cells already present at injury sites to aid healing.
The new study builds on previous research conducted back in 2011, where nanofiber microspheres were used to carry cells to injury sites to help the wounding process. The new work uses the same idea, but rather than transporting foreign cells, focuses on making better use of the cells already at the wound site.
The team developed tiny polymer spheres that are able to easily breach cell walls, carrying microRNA molecules to cells at bone wound sites. The spheres are designed to protect the molecules during transit, degrading once in place in cells at the site of the wound.
I am reading this right now. I feel like I need to go back and study it when i am finished. It is not only a basic information source but provides some nice history on the R&D of life extension. There are a number of people we can name as the big names in longer life R&D, Fossel is one of them.
The Telomerase Revolution: The Enzyme That Holds the Key to Human Aging and Will Soon Lead to Longer, Healthier Lives [Michael Fossel] on Amazon.com. *FREE* shipping on qualifying offers. One of Wall Street Journal’s Best Books for Science Lovers in 2015Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before. In recent years.
I was shocked to learn recently that one of the major reasons longevity drugs haven’t been going to human trials, despite obvious promise, is that the FDA requires that any potential drug trial has to have a disease or condition it treats. Because aging hasn’t been seen as a disease or medical condition, no drug trials have been allowed to go forward to treat it. NONE! Finally, late last year, aging has been OFFICIALLY recognized as a disease and is therefor now a valid target disease for drug trials. **sigh**.
Are we one step closer to developing compounds that can extend our lifespan?
This discussion covers eugenics, the future of capitalism, Transhumanist Bill of Rights, race, and transhumanism:
“The most important and urgent goal for any human being is to secure immortality.”
A nice telomerase overview. I’m spoiling the end: “I think it’d be great if the cure for aging came out of the land of the hobbits.”
Dr. Bill Andrews is the creator of TAM-818, the world’s most powerful anti-aging active ingredient. TAM-818 is only found in One Truth 818 serum. For more information or to purchase visit http://www.tam818.com/
William Henry “Bill” Andrews, Ph.D. is an American molecular biologist and gerontologist whose career has centered on searching for a cure for human aging. Andrews is the founder and president of the biotechnology company Sierra Sciences. In 1997, he led the team at Geron Corporation that was the first to successfully identify human telomerase.
The MMTP is testing Senolytics in an ambitious large scale mouse longevity project.
The goal of regenerative medicine is both quantity and quality whilst traditional medicine has provided quantity often at the cost of quality. Regenerative medicine proposes to reduce the frailty and decline of old age by rejuvenating the body and promoting healthy longevity. With advances in technology, research and our understanding of the aging process, this is now becoming a realistic proposition.
Some drugs already tested have been found to increase mouse lifespan such as Metformin 1,2 and Rapamycin 3.These drugs are even now moving into human clinical trials to see if the above benefits translate into people. However, there are many more promising substances that have never been properly tested and we do not know if they could extend healthy lifespan.
How fast science advances depends on how much quality research is being conducted. Currently there are few high impact studies investigating lifespan initiated each year and with so many promising substances to test this is all a painfully slow process. The Major Mouse Testing Project [MMTP] is aiming to help by rapidly testing compounds and speeding up progress.
Really nice. I may actually see the day that I can climb Everest or K2 at 100 yrs old with my cyborg body.
I like to joke that I’m technically 33 years old, but on the inside I’m 65. I’m less inclined to make that joke after spending 20 minutes or so inside Genworth’s “Aging Experience” exoskeleton. The R70i, which apparently is a barely coded reference to the fact that 70 percent of Americans will need some sort of long term care as they age, is a full body simulator that lets you experience what its like to lose your sight, hearing and even range of motion as the effects of aging creep in.
Dr Millers paper here hits the nail on the head for me about aging research and how we can speed it up.
“The time spent by gerontologists debating whether aging is a single process or many would be better devoted to trying to figure out the mechanistic links between the master clock whose existence is strongly suggested by the unitarian argument and the many cell-specific, organ-specific, and organism-wide processes that march in crude synchrony at species-specific rates.”
Yes! This is exactly the attitude to take. Too much debate and argument instead of buckling down and getting the research done to prove or disprove aging hypotheses. Cut to the chase and lets just do it.
However, in recent decades, scientific researchers in the field of aging, have found that it is indeed possible to slow down aging in animal test subjects!
This can be done by various means, including dietary and genetic interventions.
One of the most noteworthy researchers in the field is Dr Richard Miller.
The MMTP introduces – Dr Richard A Miller.
Dr Richard Miller MD, PhD, Is a professor of pathology at Michigan University, director of the Nathan Shock centre for biological aging and director of the Paul F Glenn centre for aging research.
He graduated Haverford college in 1971 with a BA, then went on to gain an MD and PhD at Yale University.
Dr Miller has held his current position at Michigan University since 1990.
He has acted as advisor for both The National Institute On Aging, and The American Federation For Aging Research.
An Aging Suit: This Exoskeleton lets you know what it feels like to get older.
Interesting use of the latest tech being shown at the largest consumer electronics show in the world CES 2016.
Iyaz Akhtar donned a 40-pound suit complete with a helmet to find out what it’s like to live with the physical pain that comes with ageing.
