Lifeboat Foundation

Researchers have used 3D nanotechnology to successfully grow human retinal cells, opening the door to a new way of treating age-related macular degeneration, a leading cause of blindness in the developed world.

In age-related macular degeneration (AMD), the macula, the part of the retina that controls sharp, straight-ahead vision, deteriorates and causes blurring in the central field of vision.

There are two types of AMD, ‘dry’ and ‘wet.’ Dry AMD is where the RPE cells in the macula break down, causing vision loss over time. It’s the most common type and mostly affects older people. In the rarer wet AMD, abnormal blood vessel growth into the macula causes fluid and blood leakage, damaging the retina and destruction of the RPE cells, leading to a rapid loss of vision.

An expert on aging thinks humans could live to be 1,000 years old—with a few tweaks to our genetic “software”.

Science: In my opinion the main cause of aging is the accumulation of mutations in DNA 🧬 more than telomere size reduction or “toxin’s”. But the control of these “toxins” together with drug’s that simulate the restriction of calories and the transfusion of blood from young people to old people. And future drugs to make the telomeres grow again.

These four treatments together maybe can promote life extension. I am also enthusiastic in regenerative treatment with stem cells and “replace” old organs by new one’s growing in lab from stem cells. However I believe that immortality only when you make the enzymes “fix” in 100% the mutations caused by radicals.

High levels of toxic chemicals in the body, such as formaldehyde, which is best known as an embalming agent, have recently been found to be naturally made by cells and also to cause ageing.

Continue reading “Scientists in breakthrough towards secret of eternal youth” »

Aging process slows when older mice share circulatory system of young; the longer the animals shared circulatory systems, the more durable the benefits.

“Many experts assumed that after birth, the thymus played little role in the development of these cells as we age, but we now know this little unsung organ helps the body prepare for a lifetime of good health,” he said.

“The more we know about these cells the greater the likelihood of unlocking new ways to treat infectious diseases and cancer.”

Researchers from the University of Melbourne, The Fiona Elsey Cancer Research Institute, Federation University, Peter Doherty Institute for Infection and Immunity, Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine, The Royal Children’s Hospital and the Walter and Eliza Hall Institute of Medical Research also contributed to the findings.

https://youtube.com/watch?v=TpME8ShuDNg

Oliver Zolman, best known for leading tech CEO Bryan Johnson’s anti-aging process, reportedly charges up to $1,000 per hour.

When the scaffold is treated with a steroid called fluocinolone acetonide, which protects against inflammation, the resilience of the cells appears to increase, promoting growth of eye cells. These findings are important in the future development of ocular tissue for transplantation into the patient’s eye.

Scientists have found a way to use nanotechnology to create a 3D ‘scaffold’ to grow cells from the retina-paving the way for potential new ways of treating a common cause of blindness.

Researchers, led by Professor Barbara Pierscionek from Anglia Ruskin University (ARU), have been working on a way to successfully grow retinal pigment epithelial (RPE) cells that stay healthy and viable for up to 150 days. RPE cells sit just outside the neural part of the retina and, when damaged, can cause vision to deteriorate.

It is the first time this technology, called ‘electrospinning’, has been used to create a scaffold on which the RPE cells could grow, and could revolutionise treatment for one of age-related macular degeneration, one of the world’s most common vision complaints.

In this episode, I interview Dr. Robert Sapolsky, Ph.D., Professor of Biology, Neurology & Neurosurgery at Stanford University. We discuss stress, what defines short-term versus long-term stress, and how stress can be beneficial or detrimental, depending on the context. We also discuss stress mitigation and how our sense of control over stress mitigation techniques, including exercise, determine health outcomes. Dr. Sapolsky explains some of the key effects of the hormone testosterone — how it can amplify pre-existing tendencies for aggression or sexual behavior, but that it does not produce those behaviors per se. He also explains how testosterone impacts our social hierarchies, sense of confidence, and willingness to embrace challenges of different kinds. He also explains how our behaviors and perceptions shape testosterone levels. And we discuss estrogen and the powerful role it plays in brain development, health and longevity. Finally, we discuss free will, what it means to have free will, and if we have any free will, including how knowledge alone might allow us to make better decisions for ourselves and society.

#HubermanLab #Testosterone #Stress.

Continue reading “Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will | Huberman Lab Podcast #35” »

Is there such a thing as a longevity mantra? A routine or set of guidelines that can help you extend your lifespan and healthspan – in a nutshell, giving you more life in your years and more years in your life?

A new study involving over 700,000 US veterans reports that people who adopt eight healthy lifestyle habits by middle age can expect to live substantially longer than those with few or none of these habits.

While it’s a list full of the usual suspects, having such a large data set has allowed the research team to put some numbers alongside these pillars of longevity.