Hydrogels are water-rich polymeric networks mimicking the body’s extracellular matrix, making them highly biocompatible and ideal for precision medicine.
A large new study suggests that higher levels of a common amino acid called tyrosine may be linked to a shorter lifespan in men.
The research, published recently in the journal Aging, examined whether blood levels of two amino acids, phenylalanine and tyrosine, were connected to how long people live.
Amino acids are building blocks of protein. They are found in protein-rich foods such as milk, eggs and meat, and are also sold as dietary supplements.
Researchers publishing in Aging Cell have discovered that the nuclei of the cells that line injured arteries quickly become misshapen and that this leads to accelerated cellular senescence. Delivering zinc to these cells partially alleviates this dysmorphism.
Two seemingly unrelated concepts
This paper begins with a discussion of two different concepts that, on the surface, appear to be unrelated. First, the researchers discuss vascular damage, particularly in the context of surgeries; even minimally invasive procedures that involve cutting, scraping, or burning arteries must cause some level of damage. This includes such procedures as catheter implantation as a treatment for heart disease [1] and the resection of cancerous tumors [2].
Exercise works wonders throughout the human body, including the brain.
Research suggests an array of neurological benefits, such as reducing the brain’s biological age, enhancing learning and memory, and protecting against dementia.
Now, a new study offers one of the clearest glimpses yet into a suspected mechanism: after a single 20-minute session of light-to-moderate cycling, people showed changes in memory-linked brain activity.
Dick Van Dyke, the legendary American actor and comedian who starred in classics such as Mary Poppins and Chitty Chitty Bang Bang, turned 100 on December 13. The beloved actor credits his remarkable longevity to his positive outlook and never getting angry.
While longevity of course comes down to many factors – including genetics and lifestyle – there is some truth to Van Dyke’s claims.
Numerous studies have shown that keeping stress levels low and maintaining a positive, optimistic outlook are correlated with longevity.
By tracking nearly every movement of a tiny fish’s life from adolescence to death, a new Science study reveals a hidden behavioral blueprint of aging—one that can predict a fish’s age or how long an individual will live.
Mapping behavior of individual vertebrate animals across lifespan could provide an unprecedented view into the lifelong process of aging. We created a platform for high-resolution continuous behavioral tracking of the African killifish across natural lifespan from adolescence to death. We found that animals follow distinct individual aging trajectories. The behaviors of long-lived animals differed markedly from those of short-lived animals, even relatively early in life, and were linked to organ-specific transcriptomic shifts. Machine-learning models accurately inferred age and even forecasted an individual’s future lifespan, given only behavior at a young age. Finally, we found that animals progressed through adulthood in a sequence of stable and stereotyped behavioral stages with abrupt transitions, revealing precise structure for an architecture of aging.
Think transhumanism is a relatively new social and intellectual phenomenon? Guess again.
Many of the ideas characteristic of the movement have already been bantered about for literally hundreds of years—whether it be such things as radical life extension or the construction of machine minds. The Enlightenment period in particular was a fruitful time for these ideas to take flight, mostly on account of the new sciences, the rise of rationalism and secular humanism, and the waning influence of religion. Two thinkers that best exemplified Enlightenment-era proto-transhumanism were Denis Diderot and Marquis de Condorcet, and their early contributions are worth revisiting.