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Summary: A new mathematical model that identifies essential connections between neurons reveals some neural networks in the brain are more essential than others.

Source: HHMI

After a career spent probing the mysteries of the universe, a Janelia Research Campus senior scientist is now exploring the mysteries of the human brain and developing new insights into the connections between brain cells.

Researchers at the University of Houston are reporting a first-of-its-kind technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically known.

Published in The Journal of Cardiovascular Aging 0, the groundbreaking finding has the potential to become a powerful clinical strategy for treating heart disease in humans, according to Robert Schwartz, Hugh Roy and Lillie Cranz Cullen Distinguished Professor of biology and biochemistry at the UH College of Natural Sciences and Mathematics.

The new technology developed by the team of researchers uses synthetic messenger ribonucleic acid (mRNA) to deliver mutated transcription factors — proteins that control the conversion of DNA into RNA — to mouse hearts.

The talk is provided on a Free/Donation basis. If you would like to support my work then you can paypal me at this link:
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Or to support me longer term Patreon me at: https://www.patreon.com/waihtsang.

Unfortunately my internet link went down in the second Q&A session at the end and the recording cut off. Shame, loads of great information came out about FPGA/ASIC implementations, AI for the VR/AR, C/C++ and a whole load of other riveting and most interesting techie stuff. But thankfully the main part of the talk was recorded.

TALK OVERVIEW
This talk is about the realization of the ideas behind the Fractal Brain theory and the unifying theory of life and intelligence discussed in the last Zoom talk, in the form of useful technology. The Startup at the End of Time will be the vehicle for the development and commercialization of a new generation of artificial intelligence (AI) and machine learning (ML) algorithms.

We will show in detail how the theoretical fractal brain/genome ideas lead to a whole new way of doing AI and ML that overcomes most of the central limitations of and problems associated with existing approaches. A compelling feature of this approach is that it is based on how neurons and brains actually work, unlike existing artificial neural networks, which though making sensational headlines are impeded by severe limitations and which are based on an out of date understanding of neurons form about 70 years ago. We hope to convince you that this new approach, really is the path to true AI.

In the last Zoom talk, we discussed a great unifying of scientific ideas relating to life & brain/mind science through the application of the mathematical idea of symmetry. In turn the same symmetry approach leads to a unifying of a mass of ideas relating to computer and information science. There’s been talk in recent years of a ‘master algorithm’ of machine learning and AI. We’ll explain that it goes far deeper than that and show how there exists a way of unifying into a single algorithm, the most important fundamental algorithms in use in the world today, which relate to data compression, databases, search engines and also existing AI/ML. Furthermore and importantly this algorithm is completely fractal or scale invariant. The same algorithm which is able to perform all these functionalities is able to run on a micro-controller unit (MCU), mobile phone, laptop and workstation, going right up to a supercomputer.

The application and utility of this new technology is endless. We will discuss the road map by which the sort of theoretical ideas I’ve been discussing in the Zoom, academic and public talks over the past few years, and which I’ve written about in the Fractal Brain Theory book, will become practical technology. And how the Java/C/C++ code running my workstation and mobile phones will become products and services.

After some serious number crunching, a UBC researcher has come up with a mathematical model for a viable time machine.

Ben Tippett, a mathematics and physics instructor at UBC’s Okanagan campus, recently published a study about the feasibility of . Tippett, whose field of expertise is Einstein’s theory of general relativity, studies black holes and science fiction when he’s not teaching. Using math and physics, he has created a formula that describes a method for time travel.

“People think of time travel as something as fiction,” says Tippett. “And we tend to think it’s not possible because we don’t actually do it. But, mathematically, it is possible.”

Researchers from the University of Nebraska-Lincoln and the University of California, Berkeley, have developed a new photonic device that could get scientists closer to the “holy grail” of finding the global minimum of mathematical formulations at room temperature. Finding that illusive mathematical value would be a major advancement in opening new options for simulations involving quantum materials.

Many scientific questions depend heavily on being able to find that mathematical value, said Wei Bao, Nebraska assistant professor of electrical and computer engineering. The search can be challenging even for modern computers, especially when the dimensions of the parameters—commonly used in quantum physics—are extremely large.

Until now, researchers could only do this with polariton optimization devices at extremely low temperatures, close to about minus 270 degrees Celsius. Bao said the Nebraska-UC Berkeley team “has found a way to combine the advantages of light and matter at suitable for this great optimization challenge.”

Circa 2019


According to string theory, all particles and fundamental forces arise from the vibrational states of tiny strings. For mathematical consistency, these strings vibrate in 10-dimensional spacetime. And for consistency with our familiar everyday experience of the universe, with three spatial dimensions and the dimension of time, the additional six dimensions are “compactified” so as to be undetectable.

Different compactifications lead to different solutions. In string theory, a “solution” implies a vacuum of spacetime that is governed by Einstein’s theory of gravity coupled to a quantum field theory. Each solution describes a unique universe, with its own set of particles, fundamental forces and other such defining properties.

Some string theorists have focused their efforts on trying to find ways to connect string theory to properties of our known, observable universe—particularly the standard model of particle physics, which describes all known particles and all their mutual forces except gravity.

Marianne StebbinsWhat does this solve that isn’t already handled by air and water?

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Anne KristoffersenTurn the Bering Strait Crossing into a bridge arcology and the project will handsomely pay for itself in a sustainable way.

The Diomede Bridge ArcoCity could become a vastly important city-state, essentially having a millions-strong settlement there w… See more.

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Jose Ruben Rodriguez Fuentes shared a link.

It’s said that the clock is always ticking, but there’s a chance that it isn’t. The theory of “presentism” states that the current moment is the only thing that’s real, while “eternalism” is the belief that all existence in time is equally real. Find out if the future is really out there and predictable—just don’t tell us who wins the big game next year.

This video is episode two from the series “Mysteries of Modern Physics: Time”, Presented by Sean Carroll.
Learn more about the physics of time at https://www.wondrium.com/YouTube.

00:00 Science and Philosophy Combine When Studying Time.
2:30 Experiments Prove Continuity of Time.
6:47 Time Is Somewhat Predictable.
8:10 Why We Think of Time Differently.
8:49 Our Perception of Time Leads to Spacetime.
11:54 We Dissect Presentism vs Eternalism.
15:43 Memories and Items From the Past Make it More Real.
17:47 Galileo Discovers Pendulum Speeds Are Identical.
25:00 Thought Experiment: “What if Time Stopped?”
29:07 Time Connects Us With the Outside World.

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