Lifeboat Foundation

The Future of Management Wargaming, Now! By Mr. Andres Agostini

This is an excerpt from the conclusion section of, “…The Future of Management Wargaming , Now…!” that discusses some management theories and practices. To read the entire piece, just click the link at the end of article:

In addition to being aware and adaptable and resilient before the driving forces reshaping the current present and the as-of-now future, there are some extra management suggestions that I concurrently practice:

a) “…human knowledge is doubling every ten years [as per the 1998 standards]…”

b) "...computer power is doubling every eighteen months. the internet is doubling every year. the number of dna sequences we can analyze is doubling every two years…”

Continue reading “The Future of Management Wargaming, Now!” »

The Future of Skunkworks Management, Now! By Mr. Andres Agostini

This is an excerpt from the conclusion section of, “…The Future of Skunkworks Management, Now!…” that discusses some management theories and practices and strategies. To view the entire piece, just click the link at the end of this post:

Peter Drucker asserted, “…In a few hundred years, when the story of our [current] time is written from a long-term perspective, it is likely that the most important event those historians will see is not technology, not the Internet, not e-commerce [not so-called ‘social media’]. IT is an unprecedented change in the human condition. For the first time ─ literally ─ substantial and growing numbers of people have choices. for the first time, they will have to manage themselves. And society is totally unprepared for it…”
Please see the full presentation at http://goo.gl/FnJOlg

Applied Omniscience in Transformative and Integrative Risk Management! By Mr. Andres Agostini

This is an excerpt from the presentation, “…Applied Omniscience in Transformative and Integrative Risk Management!…” that discusses some management theories and practices. To read the entire piece, just click the link at the end of article:

Please see the graphic at http://lnkd.in/dUstZEk

This is an excerpt from, “Futuretronium Book” by Mr. Andres Agostini, that discusses some management theories and practices with the future-ready perspective. To read the entire piece, just click the link at the end of article:

“…#1 Futuretronium ® and the administration and application of the scientific method without innuendos and in crescendo as fluid points of inflections ascertain that the morrow is a thing of the past…”

”…#2 Futuretronium ®, subsequently, there is now and here available the unabridged, authoritative eclictation and elucidation of actionable knowledge from and for the incessantly arrhythmic, abrupt, antagonistic, mordant, caustic, and anarchistic future, as well as the contentious interrelationship between such future and the present…”

“…#3 Futuretronium ®, a radical yet rigorous strong-sense and critico-creative «Futures Thinking», systems approach to quintessential understanding of the complexities, subtleties, and intricacies, as well as the opportunities to be exploited out of the driving forces instilling and inflicting perpetual change into twenty-first century…”

Read the full book at http://lnkd.in/ZxV3Sz to further explore these topics and experience future-ready management practices and theories.

Megan Cully

Altering the surface of orthopaedic implants has already helped patients – and nanotech can fight infections too

One of medicine’s primary objectives is to trick the body into doing something it doesn’t want to do. We try to convince our immune systems to attack cancer cells (our immune systems don’t normally attack our own bodies), we try to convince neurons to regrow (another unnatural phenomenon), and we try to convince the body to accept foreign bits, such as someone else’s kidney or a fake bone. In order to accomplish this, we try to make parts of our bodies we don’t want, such as cancers, look foreign. We try to make foreign bits that we do want, such as orthopaedic implants, look natural. Nanotechnology, as you might have guessed, can help us do just that.

Read more

Tim Parker, Benzinga Staff Writer

Before scientists create something that has mainstream uses, it often starts as science fiction.

A new technology deep within IBM’s (NYSE: IBM [FREE Stock Trend Analysis]) Singapore research facility isn’t quite ready for the mainstream but when it is, the implications for those who suffer from fungal infections and later, other infections, could have a new ally in their fight but this ally is completely different than current treatments.

If you’re a fan of Star Trek, you’ve seen nanotechnology. These are microscopic machines that get inside machines or in this case, the body, to identify and fix problems.

Continue reading “IBM Creates Nanotechnology to Battle Fungal Infections” »

The Lifeboat community doesn’t need me to tell them that a growing number of scientists are dedicating their time and energy into research that could radically alter the human aging trajectory. As a result we could be on the verge of the end of aging. But from an anthropological and evolutionary perspective, humans have always had the desire to end aging. Most human culture groups on the planet did this by inventing some belief structure incorporating eternal consciousness. In my mind this is a logical consequence of A) realizing you are going to die and B) not knowing how to prevent that tragedy. So from that perspective, I wanted to create a video that contextualized the modern scientific belief in radical life extension with the religious/mythological beliefs of our ancestors.

And if you loved the video, please consider subscribing to The Advanced Apes on YouTube! I’ll be releasing a new video bi-weekly!

(Excerpt)

Beyond the managerial challenges (downside risks) presented by the exponential technologies as it is understood in the Technological Singularity and its inherent futuristic forces impacting the present and the future now, there are also some grave global risks that many forms of management have to tackle with immediately.

These grave global risks have nothing to do with advanced science or technology. Many of these hazards stem from nature and some are, as well, man made.

For instance, these grave global risks ─ embodying the Disruptional Singularity ─ are geological, climatological, political, geopolitical, demographic, social, economic, financial, legal and environmental, among others. The Disruptional Singularity’s major risks are gravely threatening us right now, not later.

Read the full document at http://lnkd.in/bYP2nDC

In this essay I argue that technologies and techniques used and developed in the fields of Synthetic Ion Channels and Ion Channel Reconstitution, which have emerged from the fields of supramolecular chemistry and bio-organic chemistry throughout the past 4 decades, can be applied towards the purpose of gradual cellular (and particularly neuronal) replacement to create a new interdisciplinary field that applies such techniques and technologies towards the goal of the indefinite functional restoration of cellular mechanisms and systems, as opposed to their current proposed use of aiding in the elucidation of cellular mechanisms and their underlying principles, and as biosensors.

In earlier essays (see here and here) I identified approaches to the synthesis of non-biological functional equivalents of neuronal components (i.e. ion-channels ion-pumps and membrane sections) and their sectional integration with the existing biological neuron — a sort of “physical” emulation if you will. It has only recently come to my attention that there is an existing field emerging from supramolecular and bio-organic chemistry centered around the design, synthesis, and incorporation/integration of both synthetic/artificial ion channels and artificial bilipid membranes (i.e. lipid bilayer). The potential uses for such channels commonly listed in the literature have nothing to do with life-extension however, and the field is to my knowledge yet to envision the use of replacing our existing neuronal components as they degrade (or before they are able to), rather seeing such uses as aiding in the elucidation of cellular operations and mechanisms and as biosensors. I argue here that the very technologies and techniques that constitute the field (Synthetic Ion-Channels & Ion-Channel/Membrane Reconstitution) can be used towards the purpose of the indefinite-longevity and life-extension through the iterative replacement of cellular constituents (particularly the components comprising our neurons – ion-channels, ion-pumps, sections of bi-lipid membrane, etc.) so as to negate the molecular degradation they would have otherwise eventually undergone.

While I envisioned an electro-mechanical-systems approach in my earlier essays, the field of Synthetic Ion-Channels from the start in the early 70’s applied a molecular approach to the problem of designing molecular systems that produce certain functions according to their chemical composition or structure. Note that this approach corresponds to (or can be categorized under) the passive-physicalist sub-approach of the physicalist-functionalist approach (the broad approach overlying all varieties of physically-embodied, “prosthetic” neuronal functional replication) identified in an earlier essay.

The field of synthetic ion channels is also referred to as ion-channel reconstitution, which designates “the solubilization of the membrane, the isolation of the channel protein from the other membrane constituents and the reintroduction of that protein into some form of artificial membrane system that facilitates the measurement of channel function,” and more broadly denotes “the [general] study of ion channel function and can be used to describe the incorporation of intact membrane vesicles, including the protein of interest, into artificial membrane systems that allow the properties of the channel to be investigated” [1]. The field has been active since the 1970s, with experimental successes in the incorporation of functioning synthetic ion channels into biological bilipid membranes and artificial membranes dissimilar in molecular composition and structure to biological analogues underlying supramolecular interactions, ion selectivity and permeability throughout the 1980’s, 1990’s and 2000’s. The relevant literature suggests that their proposed use has thus far been limited to the elucidation of ion-channel function and operation, the investigation of their functional and biophysical properties, and in lesser degree for the purpose of “in-vitro sensing devices to detect the presence of physiologically-active substances including antiseptics, antibiotics, neurotransmitters, and others” through the “… transduction of bioelectrical and biochemical events into measurable electrical signals” [2].

Continue reading “Intimations of Imitations: Visions of Cellular Prosthesis & Functionally-Restorative Medicine” »