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A landmark experiment published in Nature puts leading theories of consciousness to the test

For centuries, the nature of consciousness has baffled scientists and philosophers alike. What transforms neural activity into the rich, subjective experience of seeing a face, hearing a melody, or feeling the warmth of the sun?

The Cogitate Consortium, a group of researchers from across the globe, including Professor Ole Jensen from Oxford University’s departments of Experimental Psychology and Psychiatry, set out to change that. The consortium brought together the proponents of two influential theories of consciousness—Global Neuronal Workspace Theory (GNWT), led by Stanislas Dehaene, and Integrated Information Theory (IIT), proposed by Giulio Tononi—for a rigorous empirical test.

Their adversarial collaboration, a model of scientific inquiry famously advocated for by Nobel laureate Daniel Kahneman over 20 years ago, represents a fundamental shift in how science can be done. Rather than seeking to confirm pre-existing beliefs, the experiment was designed such that all predictions, methods, and interpretations were registered in advance, eliminating post-hoc rationalisations.

Childhood Adversity May Damage The Brain’s White Matter, Study Finds

Hardships in childhood could have lasting effects on the brain, new research shows, with adverse events such as family conflict and poverty potentially affecting cognitive function in kids for several years afterwards.

This study, led by a team from Brigham and Women’s Hospital in Massachusetts, looked specifically at white matter: the deeper tissue in the brain, made up of communication fibers ferrying information between neurons.

“We found that a range of adversities is associated with lower levels of fractional anisotropy (FA), a measure of white matter microstructure, throughout the whole brain, and that this is associated with lower performance on mathematics and language tasks later on,” write the researchers in their published paper.

Are wormholes possible?

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Janna Levin is a theoretical physicist and cosmologist specializing in black holes, cosmology of extra dimensions, topology of the universe, and gravitational waves.

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Klotho: A protein that promotes healthy aging and improves longevity

An international study led by the Institut de Neurociències at the UAB (INc-UAB) has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health when aging.

As we grow older, it is natural to lose and , leading to greater frailty and a higher risk of falls and serious injuries. Cognitively, neurons progressively degenerate and lose connections, while diseases such as Alzheimer’s and Parkinson’s become more prevalent. In a society where the population is steadily aging, reducing these effects is one of the main challenges for research.

Now, in an article published in Molecular Therapy, an international research team led by Professor Miguel Chillón, ICREA researcher at the INc-UAB, has shown that increasing levels of the secreted form of the Klotho protein (s-KL) improves aging in mice.

Striking intelligence of Neanderthal stone knappers revealed

University of Wollongong researchers have experimentally confirmed that changes in hammer strike angle significantly affect the fracture path and form of stone flakes produced by Neanderthals during the Middle Paleolithic.

Published in Archaeological and Anthropological Sciences, the findings contradict a widely cited fracture model that credited rock core geometry and stiffness with flaking patterns and predicted that hammer strike angle would have minimal effect on flake formation. Results suggest a greater degree of cognitive control by early human tool makers than previously recognized.

Middle Paleolithic stone tool technology is defined by deliberate core preparation to produce flakes of predetermined size and shape. First appearing in the between 200,000 and 400,000 years ago, the Levallois method is a hallmark of Neanderthal tool making in this period.

Hidden network links may predict sudden shifts like seizures and climate tipping points

The global climate is in an imbalance. Potential “tipping elements” include the Greenland ice sheet, coral reefs, and the Amazon rainforest. Together they form a network that can collapse if just one individual component tips.

Researchers from Bonn University Hospital (UKB) and the University of Bonn have now shed light on seemingly sudden and rare, often irreversible changes within a system, such as those that can be observed in the climate, the economy, social networks or even the human brain. They took a closer look at extreme events such as epileptic seizures.

Their aim was to better understand the mechanisms underlying such changes in order to ultimately make predictions. The results of their work have now been published in the journal Physical Review Research.

Jamais vu: the science behind eerie opposite of déjà vu

Our research found that the phenomenon arises when the part of the brain which detects familiarity de-synchronises with reality. Déjà vu is the signal which alerts you to this weirdness: it is a type of “fact checking” for the memory system.

But repetition can do something even more uncanny and unusual. The opposite of déjà vu is “jamais vu”, when something you know to be familiar feels unreal or novel in some way. In our recent research, which has just won an Ig Nobel award for literature, we investigated the mechanism behind the phenomenon.

Jamais vu may involve looking at a familiar face and finding it suddenly unusual or unknown. Musicians have it momentarily – losing their way in a very familiar passage of music. You may have had it going to a familiar place and becoming disorientated or seeing it with “new eyes”

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