Lifeboat Foundation

LEAF attended the first Longevity and Cryopreservation Summit in Madrid recently. Here is another report from Elena Milova from the conference.

Elena Milova brings us another interesting interview from the recent International Longevity and Cryopreservation Summit where she caught up with Senior Scientist at the National Scientific and Technical Research Council (CONICET) of Argentina Dr. Rodolfo Gustavo Goya.

Continue reading “Dr. Rodolfo Goya – Could Yamanaka Factors Delay Human Aging?” »

Do you remember the details of your very first birthday? Of course you don’t. But Rebecca Sharrock does, because the 27-year-old from Brisbane has got something called Highly Superior Autobiographical Memory (HSAM). It’s a condition that stops people from being able to forget anything, and it’s thought that only around 60–80 people in the world have it. As a result, Rebecca is able to recall every part of her life in vivid detail, whether it be the dreams she had at eighteen months old or being photographed in a car just 12 days after her birth!

“My parents carried me to the driver’s seat of the car (my father’s idea) and placed me down upon it for a photo,” she wrote in a recent blog post. “As a newborn child I was curious as to what the seat cover and steering wheel above me were. Though at that age I hadn’t yet developed the ability to want to get up and explore what such curious objects could be.” As if this isn’t impressive enough, she can even recite the entire collection of Harry Potter books! She’s also currently writing her own book about her experiences, called My Life is a Puzzle, and it sounds as if the contents are going to be very memorable indeed. (h/t)

Continue reading “Meet The Woman Who Can Remember Every Day Of Her Life. There Are Only 80 People Like That Worldwide” »

Scientists remain skeptical about an experimental approach to reverse brain death.

• By Kate Sheridan, STAT on June 1, 2017

American neuroscientist Dean Buonomano believes that your brain might be processing the world around you in a totally different manner than how you think you’re perceiving it. We’d like to believe that our brains take in information on a first-come first-serve basis, but in actuality our brains are operating more like a cross between a tour guide and an overworked line cook at a busy diner. The tour guide tells you what’s going on while the line cook side gets everything ready behind the scenes. Together, this creates a conscious reality that Buonomano describes as a “a narrative created for our viewing pleasure by our unconscious brain.”

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By Kim Thurler, Tufts University

(MEDFORD/SOMERVILLE, Mass.) — Changing the natural electrical signaling that exists in cells outside the nervous system can improve resistance to life-threatening bacterial infections, according to new research from Tufts University biologists. The researchers found that administering drugs, including those already used in humans for other purposes, to make the cell interior more negatively charged strengthens tadpoles’ innate immune response to E. coli infection and injury. This reveals a novel aspect of the immune system – regulation by non-neural bioelectricity – and suggests a new approach for clinical applications in human medicine. The study is published online May 26, 2017, in npj Regenerative Medicine, a Nature Research journal.

“All cells, not just nerve cells, naturally generate and receive electrical signals. Being able to regulate such non-neural bioelectricity with the many ion channel and neurotransmitter drugs that are already human-approved gives us an amazing new toolkit to augment the immune system’s ability to resist infections,” said the paper’s corresponding author Michael Levin, Ph.D., Vannevar Bush Professor of Biology and Director of the Allen Discovery Center at Tufts and the Tufts Center for Regenerative and Developmental Biology in the School of Arts and Sciences. Levin is also an Associate Faculty member of the Wyss Institute of Biologically Inspired Engineering at Harvard University.

Continue reading “Bioelectricity is a new weapon to fight dangerous infection” »

The genetic makeup of any given brain cell differs from all others. That realization may provide clues to a range of psychiatric diseases.

• By Simon Makin on May 3, 2017

Brain balls sound like something straight out of a Tim Burton movie: starting as stem cells harvested from patients, they eventually develop into masses of living neurons, jumbled together in misshapen blobs.

Just like the developing brain, these neurons stretch and grow, reaching out skinny branches that grab onto others to form synapses—junctions where one neuron talks with the next.

Continue reading “Bizarre Mini Brains Offer a Fascinating New Look at the Brain” »

• Researchers have constructed a laboratory model for a unique neurological disorder by transforming patients’ own cells using stem cell technology.
• This innovation could also benefit the research of other neurological disorders that may also have roots in a dysfunctional blood-brain barrier, like Alzheimer’s disease and Huntington’s disease.

The human body is a melding of different systems designed to function well together. In some cases, however, a mechanism that protects the body can also cause it harm, like with the specialized shield of endothelial cells — called the blood-brain barrier — that keeps toxins in the blood from entering the brain.