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Tiny sea creatures reveal the ancient origins of neurons

A study in the journal Cell sheds new light on the evolution of neurons, focusing on the placozoans, a millimeter-sized marine animal. Researchers at the Center for Genomic Regulation in Barcelona find evidence that specialized secretory cells found in these unique and ancient creatures may have given rise to neurons in more complex animals.

Placozoans are tiny animals, around the size of a large grain of sand, which graze on algae and microbes living on the surface of rocks and other substrates found in shallow, warm seas. The blob-like and pancake-shaped creatures are so simple that they live without any body parts or organs.

These animals, thought to have first appeared on Earth around 800 million years ago, are one of the five main lineages of animals alongside Ctenophora (), Porifera (sponges), Cnidaria (corals, sea anemones and jellyfish) and Bilateria (all other animals).

Scientists discover a therapeutic target for Alzheimer’s disease

Scientists at Université Laval and the University of Lethbridge have succeeded in reversing certain cognitive manifestations associated with Alzheimer’s disease in an animal model of the disease. Their results have been published in the scientific journal Brain.

Although this has yet to be demonstrated in humans, we believe that the mechanism we have uncovered constitutes a very interesting therapeutic target, because it not only slows down the progression of the disease but also partially restores certain cognitive functions.

Brain in a Dish: Bio-Computing’s Rise and Ethics in the Age of Living Machines

Summary: The revolutionary field of bio-computing is making waves as DishBrain, a neural system combining 800,000 living brain cells, learns to play Pong. Recognizing the pressing need for ethical guidelines in this emerging domain, the pioneers behind DishBrain have joined forces with bioethicists in a study.

The research explores the moral considerations around biological computing systems and their potential consciousness. Beyond its innovation, the technology offers vast environmental benefits, potentially transforming the energy-consuming IT industry.

Strange Mathematical Pattern Found in The Cells of The Human Body

From the oxygen-carrying corpuscles in our blood to the branching neurons that govern our thoughts, our body is built of a dazzling variety of cells.

Researchers from institutions in Germany, Canada, Spain, and the US have published a comprehensive study of how many individual cells of each type there are in typical bodies.

Based on an exhaustive analysis of over 1,500 published sources, most adult males contain a total of around 36 trillion cells, while adult females tend to have some 28 trillion cells. A 10-year-old child, by comparison, would have in the region of 17 trillion.

From Human Uniqueness to Mental Imagery: This Week’s Top 5 Neuroscience Insights, September 17, 2023

Summary: New research delves into the distinctive human trait of sequential memory, setting us apart from bonobos. A recent study has also highlighted the joy in chasing passions over accomplishments. Groundbreaking discoveries show the human brain’s computational prowess, mirroring high-powered computers.

Additionally, the footprint of Big Tobacco is evident in the modern American diet through the promotion of hyperpalatable foods. Lastly, understanding the range of mind’s visualization abilities, from hyperphantasia to aphantasia, opens avenues for innovative treatments.

The Alzheimer’s Treatment Landscape: Leqembi vs. Donanemab

With the demise of Roche’s gantenerumab in November 2022, the Alzheimer’s disease space became a two-horse race between Eisai and Biogen’s Leqembi (lecanemab) and Eli Lilly’s donanemab. One, Leqembi, received full FDA approval in July; the other, donanemab, is widely expected to secure the agency’s approval before the end of 2023.


With a potential combined market value of $30 billion, BioSpace takes a deep dive into the Phase III data supporting Eisai and Biogen’s Leqembi and Eli Lilly’s investigational donanemab.