Lifeboat Foundation

Using his knowledge of how genes are organized and repaired in human cells, Dr. Graham Dellaire, Dalhousie Medical School’s Cameron Research Scientist in Cancer Biology, has developed a technique that could make gene therapy more effective and safer to use. His work was recently published in Nucleic Acids Research and Nature.

CRISPR, named 2015’s breakthrough discovery of the year, stands for “Clustered Regularly-Interspaced Short Palindromic Repeats.” It can accurately target and edit DNA, offering the potential to cure genetic diseases and find new treatments for cancer.

To apply CRISPR in non-dividing cells—such as those in muscle and brain tissue—researchers must first make them behave like cells that divide. They do this by turning on a cellular process called homologous recombination, which protects DNA; the recombination allows a cell’s genes to be manipulated and rearranged without the possibility of causing more harm than good.

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The first step to understanding how any system works is to identify its parts.

In a pair of papers published Thursday in Cell, researchers from the Mortimer B. Zuckerman Mind Brain and Behavior Institute announced that they identified 50 different types of inhibitory interneurons—neurons that play an important role in regulating movement—in mice spines. This is the first comprehensive classification of spinal inhibitory interneurons.

The researchers also found that types of interneurons cluster and form connections with motor neuron pools, which are groups of motor neurons tied to the movement of a single muscle. This discovery suggests that different interneuron types have distinct purposes related to movement, which could help researchers better understand motor control in the nervous system.

Continue reading “New method to classify interneurons could lead to better understanding of motor control” »

A 3D-printed layered structure that incorporates neural cells to mimic the structure of brain tissue has been created by researchers at the ARC Centre of Excellence for Electromaterials Science (ACES) in Australia, and it could have major consequences in studying and treating conditions such as schizophrenia and Alzheimer’s. The three-dimensional structure will allow scientists to better understand the complex nature of the brain and its 86 billion nerve cells. We look at the benefits and risks of this scientific breakthrough on the Lip News with Jose Marcelino Ortiz and Jo Ankier.

http://motherboard.vice.com/read/researchers-are-getting-clo…ing-brains

Continue reading “3D-Printed Brain Tissue a Success” »

http://www.scienceandnonduality.com

John Hagelin, Director of the Institute of Science, Technology and Public Policy Director of the Board of Advisors for the David Lynch Foundation.

Continue reading “Is Consciousness the Unified Field? A Field Theorist’s Perspective — John Hagelin, SAND11” »

The electromagnetic theories of consciousness propose that consciousness can be understood as an electromagnetic phenomenon.

Thanks to the work of a small group neuroscientists and theoretical physicists over the last few years, we may finally have found a way of analyzing the mysterious, metaphysical realm of consciousness in a scientific manner. The latest breakthrough in this new field, published by Max Tegmark of MIT, postulates that consciousness is actually a state of matter. “Just as there are many types of liquids, there are many types of consciousness,” he says. With this new model, Tegmark says that consciousness can be described in terms of quantum mechanics and information theory, allowing us to scientifically tackle murky topics such as self awareness, and why we perceive the world in classical three-dimensional terms, rather than the infinite number of objective realities offered up by the many-worlds interpretation of quantum mechanics.

Consciousness has always been a tricky topic to broach scientifically. After all, science deals specifically with effects that can be observed and described mathematically, and consciousness has heretofore successfully evaded all such efforts. In most serious scientific circles, merely mentioning consciousness might result in the rescinding of your credentials and immediate exile to the land of quacks and occultists. (Read: How to create a mind, or die trying.)

In SELF/LESS, a dying old man (Academy Award winner Ben Kingsley) transfers his consciousness to the body of a healthy young man (Ryan Reynolds). If you’re into immortality, that’s pretty good product packaging, no?

But this thought-provoking psychological thriller also raises fundamental and felicitous ethical questions about extending life beyond its natural boundaries. Postulating the moral and ethical issues that surround mortality have long been defining characteristics of many notable stories within the sci-fi genre. In fact, the Mary Shelley’s age-old novel, Frankenstein, while having little to no direct plot overlaps [with SELF/LESS], it is considered by many to be among the first examples of the science fiction genre.

Continue reading “Never Say Die – SELF/LESS from Science-Fiction to -Fact” »

US Military likes Google Earth for training missions.

Closed off from all non-essential personnel in a secured, vault-like work environment known as a Sensitive Compartmentalized Information Facility, the 204th Intelligence Squadron is a mystery to those outside the squadron.

If you have the “blues” eat some “greens”.

You can be in excellent physical shape, with low cholesterol, a healthy body weight and good overall physical fitness — but that doesn’t necessarily mean you’re healthy.