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Archive for the ‘neuroscience’ category: Page 595

Feb 27, 2020

Brain wiring could be behind learning difficulties, say experts

Posted by in category: neuroscience

Scientists say current system for labelling children with difficulties is ‘too simple’.

Feb 26, 2020

‘Shocked’ scientists find brain parasites in baby lizards still in shells

Posted by in category: neuroscience

Scientists found parasitic worms in the brains of lizard embryos. How did they get there?

Feb 26, 2020

Brain injury diagnosed with a finger prick and an optofluidic chip

Posted by in categories: computing, neuroscience

Researchers in the UK claim to have developed a microfluidic chip that can rapidly tell whether someone has suffered a traumatic brain injury from a finger-prick blood sample. The optofluidic device detects a biomarker linked to brain injury, based on the way that it scatters light (Nat. Biomed. Eng. 10.1038/s41551-019‑0510-4).


An optofluidic device uses Raman spectroscopy to detect a biomarker in blood associated with traumatic brain injury.

Feb 25, 2020

The genetic secret of night vision

Posted by in categories: biotech/medical, genetics, neuroscience

One of the most remarkable characteristics of the vertebrate eye is its retina. Surprisingly, the sensitive portions of the photoreceptor cells are found on the hind side of the retina, meaning that light needs to travel through living neural tissue before it can be detected. While the origin of the high optical quality of the retina remain largely uninvestigated, it has long been proposed that a peculiar DNA organization would serve to improve vision in nocturnal mammals. Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden now showed that the optical quality of the mouse retina increases in the first month after birth that imparts improved visual sensitivity under low light conditions. This improvement is caused by a compact organization of the genetic material in the cell nucleus of rod photoreceptor cells that responsible for dim light vision.

Our retina is an amazing feature of the eye of vertebrates. This -sensitive layer of is lining the back of the eye-ball and acts as a screen for images projected by the lens. The retina has a thickness of 130 to 500 micrometer and is composed of five layers of dense . Since the sensitive portions of the photoreceptor cells are found on the hind side of the retina, light needs to travel through this dense neural tissue to reach the photoreceptors. Researchers suggested that a certain compact arrangement of DNA in the cell nucleus of the rod photoreceptors could improve night vision in nocturnal animals but it remained unclear if and how would benefit from this organization of genetic material.

Scientists around the research group leader Moritz Kreysing at the Max Planck Institute of Molecular Cell Biology and Genetics together with colleagues from the TU Dresden and the Biozentrum at the Ludwig Maximilians Universität in Munich wanted to find out, if and why cells of retinal neural cells are optically special and what the implications for the transparency of the retina are. Transparency in this context means that each rod cell scatters less light, which causes it to be more transparent.

Feb 25, 2020

KLOTHO, new Intelligence Quotient boosting gene found

Posted by in categories: biotech/medical, genetics, life extension, neuroscience, sex

WASHINGTON: Scientists have found that people who have a variant of a longevity gene have improved brain skills such as thinking, learning and memory. Researchers found that increasing levels of the gene, called KLOTHO, in mice made them smarter, possibly by increasing the strength of connections between nerve cells in the brain.

“This could be a major step toward helping millions around the world who are suffering from Alzheimer’s disease and other dementias,” said Dena Dubal, an assistant professor of neurology, the David A Coulter Endowed Chair in Aging and Neurodegeneration at the University of California San Francisco (UCSF) and the lead author of the study published in Cell Reports. “If we could boost the brain’s ability to function, we may be able to counter dementias,” Dubal said.

People who have one copy of a variant, or form, of the KLOTHO gene, called KL-VS, tend to live longer and have lower chances of suffering a stroke whereas people who have two copies may live shorter lives and have a higher risk of stroke. In the study, researchers found that people who had one copy of the KL-VS variant performed better on a battery of cognitive tests than subjects who did not have it, regardless of age, sex or the presence of the apolipoprotein 4 gene, the main genetic risk factor for Alzheimer’s disease.

Feb 25, 2020

How Bionic Limbs Are Changing Lives | VICE on HBO

Posted by in categories: bioengineering, computing, cyborgs, neuroscience, transhumanism

A bionic revolution is brewing, as recent advancements in bioengineering have brought about scientific breakthroughs in rehabilitation for people with disabilities. The most cutting edge research is happening inside the human brain, where implanted technology allows people to communicate directly with computers, using their thoughts.

VICE’s Wilbert L. Cooper travels to Zurich to see the first-ever bionic Olympics and discovers a host of technologies that are expanding what it means to be human.

Continue reading “How Bionic Limbs Are Changing Lives | VICE on HBO” »

Feb 25, 2020

Gum disease, inflammation, hardened arteries may be linked to stroke risk

Posted by in categories: biotech/medical, neuroscience

Atherosclerosis progresses is driven by chronic inflammation, the more sources of low-grade, smoldering inflammation, the faster atherosclerosis could develop. Gum disease is one such source of inflammation and is associated with a higher incidence of strokes.


Patients with gum disease were three times as likely to have a stroke involving blood vessels in the back of the brain, which controls vision, coordination and other vital bodily functions; and.

Feb 24, 2020

Scientists Jump-Started Consciousness in Monkeys

Posted by in categories: biotech/medical, neuroscience

Built on decades of previous research, a team from the University of Wisconsin-Madison teased out a tiny chunk of brain tissue within the thalamus, a nub above the brain stem, as a critical part of NCC. As proof of concept, they gave it several bouts of electrical shocks, and restored awareness in unconscious monkeys under heavy anesthesia.

The crux? As soon as the electrical stimulation stopped, the monkeys’ awareness also slipped away.

Although the thalamus has long been thought of as somehow involved in supporting consciousness, the study is one of the first to pinpoint exact neural circuits—highways between the thalamus and parts of the cortex—as “switches” for consciousness that we can control using brain stimulation. And that’s wonderful news for comatose patients.

Feb 24, 2020

Are stem cells really the key to making humans live longer?

Posted by in categories: biotech/medical, life extension, neuroscience

But apart from a few small-scale examples, the only stem cell-based medical treatment practised in clinics uses haematopoietic stem cells found in the blood and bone marrow – which only produce blood cells – for transplants in blood cancer patients. These cells are taken from a patient’s sibling or an unrelated donor, before being infused into a patient’s blood, or they’re taken from a patient’s own blood before being reinfused. The procedure has been used to treat blood malignancies for almost half a century, and recently multiple sclerosis too. So how likely is it that the predictions about stem cells’ longevity-enhancing powers will become a reality?


Startups are offering stem cells as the cure to everything from age-related illness to wrinkles. But the science is far from clear-cut.

Feb 23, 2020

A light-sensitive compound enables heatless membrane modulation in photoswitches

Posted by in categories: biotech/medical, neuroscience

Optical technologies that can be used to modulate neuronal activity are opening up exciting possibilities for research in neuroscience and biology. Optical tools allow neuroscientists to excite and inhibit neurons or areas of the brain at will. They can thus be used to investigate the function of specific brain circuits or regions, as well as to identify new potential treatments for neurological and psychiatric diseases.

The generation of tethered azobenzene photoswitches targeted at bilayers or linked to is a pioneering optical technique that could further aid the study of the human brain. This technique, however, particularly when implemented at high light intensities, can lead to a considerable increase in temperature and can thus be harmful to neurons when used repeatedly.

To overcome this limitation, researchers at the Italian Institute of Technology (IIT) in collaboration with Politecnico di Milano, have recently created a new light-sensitive azobenzene compound, dubbed Ziapin2, which can be used to build photoswitches that do not increase in temperature when irradiated with visible light. This new compound, introduced in a paper published in Nature Nanotechnology, partitions into the with a high stability, enabling its thinning and an increased capacitance at a steady state.