Toggle light / dark theme

Hidden tunnels which link the human skull to the brain have been discovered by scientists, leading to hopes the breakthrough may help in stroke and Alzheimer’s research.

Researchers believe that the passages provide a quick channel for immune cells to reach the brain from the bone marrow in the skull.

Previously it was through that immune cells formed in the bone marrow of the limbs was transported up to the brain to clear out infection.

Read more

If you’ve ever experienced jet lag, you are familiar with your circadian rhythm, which manages nearly all aspects of metabolism, from sleep-wake cycles to body temperature to digestion. Every cell in the body has a circadian clock, but researchers were unclear about how networks of cells connect with each other over time and how those time-varying connections impact network functions.

In research published Aug. 27 in PNAS, researchers at Washington University in St. Louis and collaborating institutions developed a unified, data-driven computational approach to infer and reveal these connections in biological and chemical oscillatory networks, known as the topology of these , based on their time-series data. Once they establish the topology, they can infer how the agents, or cells, in the network work together in synchrony, an important state for the brain. Abnormal synchrony has been linked to a variety of brain disorders, such as epilepsy, Alzheimer’s disease and Parkinson’s disease.

Jr-Shin Li, professor of systems science & mathematics and an applied mathematician in the School of Engineering & Applied Science, developed an algorithm, called the ICON (infer connections of networks) method, that shows for the first time the strength of these connections over time. Previously, researchers could only determine whether a connection existed between networks.

Read more

Jason Padgett grew up struggling in school — until one night in 2002 when he was attacked in a bar and everything changed. Padgett said after the incident, he was using areas of the brain he didn’t previously have access to; he experienced choppy vision, was drawing intricate shapes and was seeing complex mathematical objects everywhere. Dr. Darold Treffert, a world renowned expert on savants, later diagnosed Padgett with acquired savant syndrome, which explained Padgett’s new skills. Padgett joins Megyn Kelly TODAY to share his story.

Read more

Scientists at Harvard Medical School have discovered that a protein called TMC1 converts sound and head motion into electrical signals, thus enabling hearing and balance.

The findings were published this week in the journal https://www.cell.com/neuron/fulltext/S0896-6273(18)30631...ctitle0120\">Neuron.

Sensitivity to sound has been a powerful evolutionary force, but the precise molecular mechanisms that enable hearing have not been fully identified.

Read more

Today, we want to draw your attention to a recent study showing an association between the accumulation of Tau proteins, which are misfolded proteins that typically indicate Alzheimer’s disease and senescent cells.

Unfortunately, this journal paper is hidden behind a paywall, as is 70% of scientific data; this is an unacceptable situation for science and the sharing of knowledge. However, thanks to the work of Sci-Hub, a website that bypasses paywalls and offers free access to all scientific papers, you can read it without spending a dime.

Read more

Level 4 – Awareness + World model: Systems that have a modeling system complex enough to create a world model: a sense of other, without a sense of self – e.g., dogs. Level 4 capabilities include static behaviors and rudimentary learned behavior.

Level 5 – Awareness + World model + Primarily subconscious self model = Sapient or Lucid: Lucidity means to be meta-aware – that is, to be aware of one’s own awareness, aware of abstractions, aware of one’s self, and therefore able to actively analyze each of these phenomena. If a given animal is meta-aware to any extent, it can therefore make lucid decisions. Level 5 capabilities include the following: The “sense of self”; Complex learned behavior; Ability to predict the future emotional states of the self (to some degree); The ability to make motivational tradeoffs.

Level 6 – Awareness + World model + Dynamic self model + Effective control of subconscious: The dynamic sense of self can expand from “the small self” (directed consciousness) to the big self (“social group dynamics”). The “self” can include features that cross barriers between biological and non-biological – e.g., features resulting from cybernetic additions, like smartphones.

Level 7 – Global awareness – Hybrid biological-digital awareness = Singleton: Complex algorithms and/or networks of algorithms that have capacity for multiple parallel simulations of multiple world models, enabling cross-domain analysis and novel temporary model generation. This level includes an ability to contain a vastly larger amount of biases, many paradoxically held. Perspectives are maintained in separate modules, which are able to dynamically switch between identifying with the local module of awareness/perspective or the global awareness/perspective. Level 7 capabilities involve the same type of dynamic that exists between the subconscious and directed consciousness, but massively parallelized, beyond biological capacities.

Read more