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Study unveils how specific cortico-thalamic connectivity patterns influence essential tremor suppression with deep brain stimulation (DBS). It highlights the contralateral thalamus as a pivotal driver of tremor modulation and potential pathways for enhanced intervention strategies.

Science and Technology: This was previously thought to be impossible:

This was previously thought to be impossible:

Scientists were astonished to find that recirculating a cocktail of preserving agents through a severed pig’s head caused the animal’s brain to show signs of life.

Continue reading “Doctors Intrigued by Treatment That Makes Dead Brains Show Signs of Life” »

Although it is widely recognized that sleep boosts cognitive performance, the neural mechanisms underlying this effect—especially those associated with non-rapid eye movement (NREM) sleep—are still not well understood.

A new study by a team of researchers at Rice University and Houston Methodist’s Center for Neural Systems Restoration and Weill Cornell Medical College, coordinated by Rice’s Valentin Dragoi, has nonetheless uncovered a key mechanism by which sleep enhances neuronal and behavioral performance, potentially changing our fundamental understanding of how sleep boosts brainpower.

The research, published in Science, reveals how NREM sleep — the lighter sleep one experiences when taking a nap, for example — fosters brain synchronization and enhances information encoding, shedding new light on this sleep stage. The researchers replicated these effects through invasive stimulation, suggesting promising possibilities for future neuromodulation therapies in humans. The implications of this discovery potentially pave the way for innovative treatments for sleep disorders and even methods to enhance cognitive and behavioral performance.

As we explore space outside our solar system, genetic engineering offers hope for overcoming challenges like radiation exposure and the effects of microgravity. By understanding and modifying our genes, we could make astronauts more resilient and improve their health in space. However, these advancements raise important ethical questions about safety, fairness, and long-term impacts, which must be carefully considered as we develop new space travel technologies.

We are on the edge of exploring space outside our solar system. This is not just a major advancement in technology, but a transformation for all of mankind. As we aim for the stars, we also try to understand more about ourselves. Our exploration into space will determine the future of our history. However, this thrilling adventure comes with many challenges. We need to build faster spacecraft, develop ways to live sustainably in space and deal with the physical and mental difficulties of long space missions. Genetics may help us solve some of these problems. As we travel further into space, it will be important to understand how genetics affects our ability to adapt to the space environment. This knowledge will be crucial for the success of space missions and the well-being of astronauts.

Genetics offers a hopeful path to overcoming many challenges in space exploration. As we venture further into space, it becomes essential to understand how our genes affect the way we adapt to the space environment. Genetics affects many aspects of an astronaut’s ability to survive and do well in space. It influences how the body handles exposure to radiation, deals with microgravity, and copes with isolation. Some genetic differences, like changes in the Methylene-TetraHydrofolate-Reductase (MTHR) gene, can make certain people more vulnerable to the harmful effects of radiation in space. With tools like genetic testing and personalized medicine, space agencies can now choose the best-suited astronauts and develop health strategies to improve their safety and performance in harsh space conditions.

Researchers at FutureNeuro, the SFI Research Centre for Translational Brain Science, and RCSI University of Medicine and Health Sciences, in collaboration with international partners, have developed a revolutionary technique to profile gene activity in the living human brain.

This innovative approach, published in JCI Insight, opens new avenues for understanding and treating neurological conditions like epilepsy.

Studying gene activity in the brain without requiring invasive tissue samples from surgery or post-mortem donation has been a long-standing challenge in neuroscience. By analyzing molecular traces – specifically RNA and DNA – collected from electrodes implanted in the brains of patients with epilepsy and linking these with electrical recordings from the brain, the researchers were able to take a ‘snapshot’ of gene activity in the living brain.

New experiments reveal how the brain chooses which memories to save and add credence to advice about the importance of rest.

Memory, a fundamental aspect of human cognition and consciousness, is multifaceted and extends beyond traditional conceptualizations of mental recall. This review article explores memory through various lenses, including brain-based, body-based, and cellular mechanisms. At its core, memory involves the encoding, storage, and retrieval of information. Advances in neuroscience reveal that synaptic changes and molecular modifications, particularly in the hippocampus, are crucial for memory consolidation. Additionally, body memory, or somatic memory, highlights how sensory experiences and traumatic events are stored and influence behavior, underscoring the role of implicit memory. Multiple studies have demonstrated that memories can be encoded and stored in cells. Evidence suggests that these memories can then be transferred between individuals through organ transplantation.

Some researchers propose that advancing AI to the next level will require an internal architecture that more closely mirrors the human mind. Rufin VanRullen joins Brian Greene to discuss early results from one such approach, based on the Global Workspace Theory of consciousness.

This program is part of the Big Ideas series, supported by the John Templeton Foundation.

Continue reading “Can Models of Human Consciousness Enhance AI Capabilities?” »

A new study by the University of Reading on human brain evolution has found that modern humans, Neanderthals, and other recent relatives evolved larger brains much more rapidly than earlier species. This challenges previous ideas, suggesting that brain size increased gradually within each ancient human species, rather than through sudden leaps between species.

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