Lifeboat Foundation

Some thoughts about possible communication with intelligent alliens, for more info see:

Contact with intelligent aliens would happen on their terms, not ours.

X-Prize board member Sergey Young on his new book, and the potential for a longevity X-Prize.

“We have created science and technology to extend our life, but we haven’t created life we want to extend.”–Sergey Young, Seeking Delphi™ episode #55, explaining why he believes more people do not support radical life extension.

Continue reading “#55: The Longevity Dialogs Part 3, The Science and Technology of Growing Young with Sergey Young” »

The newly formed biotech start up Halo Therapeutics, spun out from the University of Bristol, has become the latest company to join the Science Creates ecosystem.

The team is targeting new treatments for coronavirus as they expand on their exciting recent breakthrough discovery, which was published in Science Magazine.

The context

Continue reading “Halo Therapeutics join Science Creates to advance antiviral development” »

We embrace hybridized practices among different disciplines and living organisms, open knowledge and precarity as a challenge. Our current lines of research are based in the use of sound to understa…

Nad plus works for alzheimers.

In June of 2,018 the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases, and for the first time added aging.¹ The classification of aging as a disease paves the way for new research into novel therapeutics to delay or reverse age-related illnesses such as cancer, cardiovascular and metabolic disease, and neurodegeneration.^2,3 Nutrient sensing systems have been an intense focus of investigation, including mTOR (the mammalian target of rapamycin) for regulating protein synthesis and cell growth; AMPK (activated protein kinase) for sensing low energy states; and sirtuins, a family of seven proteins critical to DNA expression and aging, which can only function in conjunction with NAD+ (nicotinamide adenine dinucleotide), a coenzyme present in all living cells.⁴

Across the kingdom of life, an increase in intracellular levels of NAD+ triggers shifts that enhance survival, including boosting energy production and upregulating cellular repair.⁵ In fact, the slow, ineluctable process of aging has been described as a “cascade of robustness breakdown triggered by a decrease in systemic NAD+ biosynthesis and the resultant functional defects in susceptible organs and tissues.”⁶ Aging is marked by epigenetic shifts, genomic instability, altered nutrient sensing ability, telomere attrition, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and dysregulated intercellular communication.^7,8

By middle age, our NAD+ levels have plummeted to half that of our youth.⁹ Numerous studies have demonstrated that boosting NAD+ levels increases insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.^10,11 NAD+ levels can be increased by activating enzymes that stimulate synthesis of NAD+, by inhibiting an enzyme (CD38) that degrades NAD+, and by supplementing with NAD precursors, including nicotinamide riboside(NR) and nicotinamide mononucleotide (NMN).^12,13 A conceptual framework called NAD World, formulated over the last decade by developmental biologist Shin-ichiro Imai, MD, PhD, of Washington University School of Medicine, posits NMN as a critical, systemic signaling molecule that maintains biological robustness of the communication network supporting NAD+.⁶.

A new book, published this week, explains where aging research is heading – and what you can do today to extend your healthspan. https://www.futuretimeline.net/.…/28-the-science-and…

Editorial reviews.

“A very compelling book.” —Ray Kurzweil, inventor and futurist.

Continue reading “The science and technology of growing young” »

A month after New Shepard’s first flight carrying people into space, a science flight without crew onboard has launched from Blue Origin’s facility near Van Horn, Texas. The flight, the fourth of the year for the New Shepard program, was originally scheduled for August 25 2021, but was delayed due to a payload integration issue.

New Shepard flight NS-17 lifted off on Thursday, August 26 at 09:31 CDT local time (14:31 UTC) — after two unplanned holds — on a suborbital trajectory with an apogee over 100 kilometers, the boundary to space as recognized by the Federation Aeronautique Internationale.

Continue reading “Blue Origin launches NS-17 suborbital science mission” »

Out today.

Sergey Young is a longevity investor and visionary with the XPRIZE his mission to extend healthy lifespans of at least one billion people. To do that, Sergey founded Longevity Vision Fund to accelerate life extension technological breakthroughs and to make longevity affordable and accessible to all.

Continue reading “How To Live To 150: The Science & Tech Of Growing Young | Lifespan.io Interview” »

The 23rd SpaceX

Commonly known as SpaceX, Space Exploration Technologies Corp. is a private American aerospace manufacturer and space transportation services company that was founded by Elon Musk in 2002. Headquartered in Hawthorne, California, the company designs, manufactures, and launches advanced rockets and spacecraft.