Lifeboat Foundation

Frogs briefly treated with a five-drug cocktail administered by a wearable bioreactor on the stump were able to regrow a functional, nearly complete limb.

For millions of patients who have lost limbs for reasons ranging from diabetes to trauma, the possibility of regaining function through natural regeneration remains out of reach. Regrowth of legs and arms remains the province of salamanders and superheroes.

But in a study published in the journal Science Advances, scientists at Tufts University and Harvard University’s Wyss Institute have brought us a step closer to the goal of regenerative medicine.

For millions of patients who have lost limbs – for reasons ranging from diabetes to trauma – the possibility of regaining function through natural regeneration remains out of reach. The regrowth of legs and arms remains limited to animals such as salamanders and the realm of science fiction.

However, a new study published in the journal Science Advances, by scientists at Tufts University and Harvard University’s Wyss Institute, has brought us a step closer to the goal of regenerating human limbs.

On adult frogs, which are naturally unable to regenerate limbs, a research team succeeded in triggering regrowth of a lost leg using a five-drug cocktail applied in a silicone wearable bioreactor dome that seals over the stump for just 24 hours. That brief treatment sets in motion an 18-month period of regrowth that eventually restores a functional leg.

Recent advances in brain imaging techniques facilitate accurate, high-resolution observations of the brain and its functions. For example, functional near-infrared spectroscopy (fNIRS) is a widely used noninvasive imaging technique that employs near-infrared light (wavelength 700 nm) to determine the relative concentration of hemoglobin in the brain, via differences in the light absorption patterns of hemoglobin.

Most noninvasive brain scanning systems use continuous-wave fNIRS, where the tissue is irradiated by a constant stream of photons. However, these systems cannot differentiate between scattered and absorbed photons. A recent advancement to this technique is time-domain (TD)-fNIRS, which uses picosecond pulses of light and fast detectors to estimate photon scattering and absorption in tissues. However, such systems are expensive and complex and have a large form factor, limiting their widespread adoption.

To overcome these challenges, researchers from Kernel, a neurotechnology company, have developed a wearable headset based on TD-fNIRS technology. This device, called “Kernel Flow,” weighs 2.05 kg and contains 52 modules arranged in four plates that fit on either side of the head. The specifications and performance of the Kernel Flow system are reported in the Journal of Biomedical Optics (JBO).

Switch your disposable masks with Zephyr.

If you think your voice has been dulled by wearing masks in this pandemic, then electronics company Razer has the product for you. Zephyr Pro is a wearable mask that has a voice amplification feature in addition to built-in speakers.

In January last year, Razer had unveiled the initial concept and called it Hazel. A year later, it is now Zephyr and Razer already has a Pro version of the product. At first glance, the Zephyr Pro does… See more.

In the 2002 science fiction blockbuster film “Minority Report,” Tom Cruise’s character John Anderton uses his hands, sheathed in special gloves, to interface with his wall-sized transparent computer screen. The computer recognizes his gestures to enlarge, zoom in, and swipe away. Although this futuristic vision for computer-human interaction is now 20 years old, today’s humans still interface with computers by using a mouse, keyboard, remote control, or small touch screen. However, much effort has been devoted by researchers to unlock more natural forms of communication without requiring contact between the user and the device. Voice commands are a prominent example that have found their way into modern smartphones and virtual assistants, letting us interact and control devices through speech.

Hand gestures constitute another important mode of human communication that could be adopted for human-computer interactions. Recent progress in camera systems, image analysis and machine learning have made optical-based gesture recognition a more attractive option in most contexts than approaches relying on wearable sensors or data gloves, as used by Anderton in “Minority Report.” However, current methods are hindered by a variety of limitations, including high computational complexity, low speed, poor accuracy, or a low number of recognizable gestures. To tackle these issues, a team led by Zhiyi Yu of Sun Yat-sen University, China, recently developed a new hand gesture recognition algorithm that strikes a good balance between complexity, accuracy, and applicability.

It’s been a few years since we’ve heard from AR company Vuzix. In early 2019, it came out with its first pair of. After staying relatively quiet over the past two years, it’s now partnering with Verizon. The two didn’t share many details about their collaboration. What they did say is that they plan to find ways to commercialize AR technology for use in sports and gaming scenarios, especially those involving the need for training. The partnership will combine Vuzix’s new Shield smart glasses and the capabilities of Verizon’s 5G network.

It’s hard to say if we’ll see anything impactful come out of this agreement, but it’s not a surprise to see Verizon. Augmented, virtual and mixed reality wearables have been consistently positioned as one of the primary beneficiaries of the speed and latency enhancements promised by 5G networks. Likewise, the focus on gaming and sports isn’t surprising either. Some of the earliest locations where Verizon had 5G service was in. They’re one of few places where the carrier’s mmWave deployments shine since there’s enough density there to justify building out all the small cells required to blanket even a small area with ultrafast 5G coverage.

Part human, part robot, all business.

This new wearable robotic suit can boost human strength, and it is powered by artificial intelligence — taking human augmentation to new levels.

Continue reading “These robotic suits supercharge human workers” »

Researchers at the RIKEN Center for Emergent Matter Science (CEMS) and the RIKEN Cluster for Pioneering Research (CPR) in Japan have developed a technique to improve the flexibility of ultra-thin electronics, such as those used in bendable devices or clothing. Published in Science Advances, the study details the use of water vapor plasma to directly bond gold electrodes fixed onto separate ultra-thin polymer films, without needing adhesives or high temperatures.

As electronic devices get smaller and smaller, and the desire to have bendable, wearable, and on-skin electronics increases, conventional methods of constructing these devices have become impractical. One of the biggest problems is how to connect and integrate multiple devices or pieces of a device that each reside on separate ultra-thin polymer films. Conventional methods that use layers of adhesive to stick electrodes together reduce flexibility and require temperature and pressure that are damaging to super-thin electronics. Conventional methods of direct metal-to-metal bonding are available, but require perfectly smooth and clean surfaces that are not typical in these types of electronics.

A team of researchers led by Takao Someya at RIKEN CEMS/CPR has developed a new method to secure these connections that does not use adhesive, high temperature, or high pressure, and does not require totally smooth or clean surfaces. In fact, the process takes less than a minute at room temperature, followed by about a 12-hour wait. The new technique, called water-vapor plasma-assisted bonding, creates stable bonds between gold electrodes that are printed into ultra-thin—2 thousandths of a millimeter—polymer sheets using a thermal evaporator.

Researchers have developed a rechargeable lithium-ion battery in the form of an ultra-long fiber that could be woven into fabrics. The battery could enable a wide variety of wearable electronic devices, and might even be used to make 3D-printed batteries in virtually any shape.

The researchers envision new possibilities for self-powered communications, sensing, and computational devices that could be worn like ordinary clothing, as well as devices whose batteries could also double as structural parts.

In a proof of concept, the team behind the new battery technology has produced the world’s longest flexible fiber battery, 140 meters long, to demonstrate that the material can be manufactured to arbitrarily long lengths. The work is described today in the journal Materials Today. MIT postdoc Tural Khudiyev (now an assistant professor at National University of Singapore), former MIT postdoc Jung Tae Lee (now a professor at Kyung Hee University), and Benjamin Grena SM ‘13, Ph.D. ‘17 (currently at Apple) are the lead authors on the paper. Other co-authors are MIT professors Yoel Fink, Ju Li, and John Joannopoulos, and seven others at MIT and elsewhere.