The discovery of a protein closely involved with EGFR-KRAS signalling could help thwart pathways to resistance against RAS targeted drugs for pancreatic cancer and other KRAS-associated tumours.
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Scientists use light to create tiny molecules that could transform medicine
Researchers have developed a light-driven method for creating tiny, high-energy “housane” molecules that are valuable for drug development and materials science. These compact ring-shaped structures are difficult to produce because of the intense internal strain they contain. By using photocatalysis and carefully tuning the starting molecules, the team managed to guide the reaction into a clean and efficient pathway.
The Unambigous Alien Probe and the Von Neumann Cloud
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Cylinder Five by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/.… https://chriszabriskie.com/cylinders/ Intermission in D by Miguel Johnson https://migueljohnson.bandcamp.com/
Geordie Rose: Machine Learning is Progressing Faster Than You Think
“Machine learning is progressing faster than you think.”
Geordie Rose said that to me in 2013.
Back then, it sounded like the kind of thing a quantum computing CEO says to drum up attention. Today it reads like a weather report.
Thirteen years ago, the D-Wave founder and CTO sat down with me for over two hours and laid out a thesis most observers found extreme: machine learning would become broadly available far faster than anyone hoped, and quantum computers would help us build AI by 2029.
The 2029 date sounded like science fiction.
It does not sound like science fiction anymore.
Optoelectronic synapse shows exceptional photoresponse for neuromorphic vision
Like so much else in nature, the human visual system has both a complex structure and functional efficiency that is difficult for scientists to replicate. The system is both a sensor and a processor, with the eyes and the brain working together to resolve images with less energy use than anything people have invented.
But a technology called optoelectronic synapses can reproduce at least some of the phenomena that make human vision so successful, and a team of researchers at the National Laboratory of the Rockies (NLR) has discovered why certain materials perform so well at artificial vision and memory.
In their article “Interlayer Exciton Polarons in Mesoscopic V2O5 for Broadband Optoelectronic Synapses” published in Advanced Functional Materials, the NLR-led research team discovered the source of persistent photoconductivity—a mechanism that mirrors some of the functionality of biological synapses in the eye—for a particular vanadium-oxide material.
What if the direction of a magnet could shape the building blocks of life?
In a new discovery, researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have found that something in the direction of a magnetic field can influence how molecules of life behave at the most fundamental level and how early chemical processes linked to life may have unfolded.
The study, published in Chem and led by Prof. Yossi Paltiel (Hebrew University) and Prof. Michal Sharon (Weizmann Institute), shows that tiny differences between atoms (different isotopes) can lead to measurable changes in molecular behavior when combined with an invisible quantum property known as electron spin. Separation of the different isotopes can be achieved by magnetic surfaces.
At the center of the story is L-methionine, an amino acid, a basic building block of life. Like other biological molecules, methionine has a specific “handedness,” meaning it exists in a form that is not identical to its mirror image. This property, called chirality, is a mystery: why did nature choose one “hand” over the other?