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Sep 23, 2022

Researchers answer fundamental question of quantum physics

Posted by in category: quantum physics

An international team of physicists, with the participation of the University of Augsburg, has for the first time confirmed an important theoretical prediction in quantum physics…

Sep 23, 2022

Atomic-scale imaging reveals a facile route to crystal formation

Posted by in categories: biotech/medical, health

What do clouds, televisions, pharmaceuticals, and even the dirt under our feet have in common? They all have or use crystals in some way. Crystals are more than just fancy gemstones. Clouds form when water vapor condenses into ice crystals in the atmosphere. Liquid crystal displays are used in a variety of electronics, from televisions to instrument panels. Crystallization is an important step for drug discovery and purification. Crystals also make up rocks and other minerals. Their crucial role in the environment is a focus of materials science and health sciences research.

Scientists have yet to fully understand how crystallization occurs, but the importance of surfaces in promoting the process has long been recognized. Research from Pacific Northwest National Laboratory (PNNL), the University of Washington (UW), and Durham University sheds new light on how crystals form at surfaces. Their results were published in Science Advances.

Previous studies on crystallization led scientists to form the classical nucleation theory—the predominant explanation for why crystals begin to form, or nucleate. When crystals nucleate, they begin as very small ephemeral clusters of just a few atoms. Their makes the clusters extremely difficult to detect. Scientists have managed to collect only a few images of such processes.

Sep 23, 2022

Friend or Foe? How Mice Decide to Make Love or War

Posted by in categories: neuroscience, sex

Summary: The neural circuitry that connects olfactory information about another mouse’s sex to decision-making in the brain determines the behavioral outcome as to whether aggression or affection is expressed.

Source: CalTech.

Dog owners whose pets meet during a walk are familiar with the immediate sniffing investigation that typically ensues. Initially, the owners cannot tell whether their dogs will wind up fighting, playing, or trying to mount each other. Something is clearly happening in the dog’s brain to make it decide how to behave toward the other dog—but what is going on?

Sep 23, 2022

Soft robots that grip with the right amount of force

Posted by in category: robotics/AI

Tool use has long been a hallmark of human intelligence, as well as a practical problem to solve for a vast array of robotic applications. But machines are still wonky at exerting just the right amount of force to control tools that aren’t rigidly attached to their hands.

To manipulate said tools more robustly, researchers from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL), in collaboration with the Toyota Research Institute (TRI), have designed a system that can grasp tools and apply the appropriate amount of force for a given task, like squeegeeing up liquid or writing out a word with a pen.

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Sep 23, 2022

Metaverse is the Doom of Engineering, Thanks to its Tactless Architecture

Posted by in categories: augmented reality, blockchains, climatology, education, robotics/AI, virtual reality

Those who are venturing into the architecture of the metaverse, have already asked themselves this question. A playful environment where all formal dreams are possible, where determining aspects for architecture such as solar orientation, ventilation, and climate will no longer be necessary, where – to Louis Kahn’s despair – there is no longer a dynamic of light and shadow, just an open and infinite field. Metaverse is the extension of various technologies, or even some call them a combination of some powerful technologies. These technologies are augmented reality, virtual reality, mixed reality, artificial intelligence, blockchain, and a 3D world.

This technology is still under research. However, the metaverse seems to make a significant difference in the education domain. Also, its feature of connecting students across the world with a single metaverse platform may bring a positive change. But, the metaverse is not only about remote learning. It is much more than that.

Architecture emerged on the construction site, at a time when there was no drawing, only experimentation. Over time, thanks to Brunelleschi and the Florence dome in the 15th century, we witnessed the first detachment from masonry, a social division of labor from which liberal art and mechanical art emerge. This detachment generated different challenges and placed architecture on an oneiric plane, tied to paper. In other words, we don’t build any structures, we design them. Now, six centuries later, it looks like we are getting ready to take another step away from the construction site, abruptly distancing ourselves from engineering and construction.

Sep 23, 2022

Engineering living ‘scaffolds’ for building materials

Posted by in categories: bioengineering, biological, nanotechnology

When the inside of a mollusk shell shimmers in sunlight, the iridescence isn’t produced by colored pigments but by tiny physical structures self-assembled from living cells and inorganic components. Now, a team of researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a platform to mimic this self-assembly ability by engineering living cells to act as a starting point for building composite materials.

Engineered living (ELMs) use living as “materials scaffolds” and are a new class of material that might open the door to self-healing materials and other advanced applications in bioelectronics, biosensing, and smart materials. Such materials could mimic emergent properties found in nature—where a complex system has properties that the individual components do not have—such as iridescence or strength.

Borrowing from this complexity seen in nature, the Berkeley Lab researchers engineered a bacterium that can attach a wide range of nanomaterials to its cell surface. They can also precisely control the makeup and how densely packed the components are, creating a stable hybrid living material. The study describing their work was recently published in ACS Synthetic Biology.

Sep 23, 2022

How we are matching — or exceeding — nature’s ability to make strong, tough lightweight structural materials

Posted by in categories: energy, nanotechnology, transportation

In nature, wood, shells, and other structural materials are lightweight, strong, and tough. Significantly, these materials are made at the ambient temperature in the local environment – not at the high temperatures at which human-made structural materials are generally processed. Similar materials are difficult to make synthetically. In a review article in Nature Materials, a team of scientists assessed the common design motifs of a range of natural structural materials and determined what it would take to design and fabricate structures that mimic nature. They considered the remaining challenges to include the need for comprehensive characterization of strength and toughness to identify underlying multiscale mechanisms.

This comprehensive assessment provides new inspiration and understanding of design principles that may lead to more efficient synthetic approaches for advanced, lightweight structural materials for transportation, buildings, batteries, and energy conversion.

In the natural world, many of the structural materials (wood, shells, bones, etc.) are hybrid materials made up of simple constituents that are assembled at ambient temperatures and often have remarkable properties. Even though the constituent materials generally have poor intrinsic properties, the superior extrinsic properties of the hybrid materials are the result of the arrangement of hard and soft phases in complex hierarchical architectures, with dimensions spanning from the nanoscale to the macroscale. The resulting materials are lightweight and usually show interesting combinations of strength and toughness, even though these two key structural properties tend to be mutually exclusive. It is relatively easy to make materials that are strong or tough, but difficult to make materials that are both.

Sep 23, 2022

The Relationship Between Particular Brain Circuits and Different Aspects of Mental Well-Being

Posted by in category: neuroscience

Summary: Understanding how changes in the brain relate to changes in well-being is key to developing new targets for the treatment of mental health disorders.

Source: University of Oxford.

Associate Professor Miriam Klein-Flügge and colleagues looked at brain connectivity and mental health data from nearly 500 people. In particular, they looked at the connectivity of the amygdala—a brain region well known for its importance in emotion and reward processing.

Sep 23, 2022

Strong Link Between Gut Bacteria and Metabolites

Posted by in category: biotech/medical

Summary: Study reveals a strong connection between certain bacteria residing in the gut and metabolites, small molecules found in the blood.

Source: Uppsala University.

There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites. Such is the finding of a new study led by researchers from Uppsala University and Lund University, which is now published in the journal Nature Communications.

Sep 23, 2022

Researchers identify potential gene marker for treating pancreatic cancer

Posted by in categories: biotech/medical, genetics

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC). The researcher’s findings are published in Nature Cancer.

“Pancreatic ductal adenocarcinoma is one of the most lethal cancers,” says the paper’s senior author Zhenkun Lou, Ph.D. Dr. Lou says while Poly-ADP-ribose-polymerase inhibitors (PARPi) are now an FDA-approved option for standard maintenance therapy for patients with metastatic PDAC who harbor pathogenic germline BRCA1/2 mutations, only about 10 percent of patients with PDAC harbor pathogenic mutations of the homologous recombination (HR) genes. “This leaves most patients missing out on this encouraging treatment strategy,” says Dr. Lou.

In this study, Dr. Lou and his colleagues found that the protein METTL16 may be a new biomarker for PARPi treatment, and that PDAC with elevated expression of METTL16, may benefit from PARPi treatment.