Lifeboat Foundation

The more you know about mutations driving your cancer, the better your chances of finding the right treatments.

Even more, over 1 in 3 clinical trials require knowing your tumor profile.

Continue reading “Get an NGS test to get the right treatments” »

For the first time, a researcher at the University of Delaware College of Health Sciences in collaboration with a team at the National Institute on Aging, a division of the National Institutes of Health, has determined that the naturally occurring dietary supplement known as nicotinamide riboside (NR) can enter the brain.

The discovery was made by Christopher Martens, assistant professor of kinesiology and applied physiology and director of the Delaware Center for Cognitive Aging Research, and Dr. Dimitrios Kapogiannis, a senior investigator at the National Institute on Aging. The finding is significant because it supports the idea that NR, upon reaching the brain, can alter the metabolism of relevant biological pathways involved in neurodegenerative diseases like Alzheimer’s. Their work was recently published in the journal Aging Cell.

Upon consumption, NR is readily converted into nicotinamide adenine dinucleotide (NAD+), which is critical to cellular repair and the repair of damaged DNA.

The Vertiia’s box wing design reduces wingtip drag and ups aerodynamic efficiency, which will let it operate smoothly in urban environments.

A new study shows that extreme black holes could break the famous “no-hair” theorem, and in a way that we could detect.

West Virginia University physicists have made a breakthrough on an age-old limitation of the first law of thermodynamics.

Paul Cassak, professor and associate director of the Center for KINETIC Plasma Physics, and graduate research assistant Hasan Barbhuiya, both in the Department of Physics and Astronomy, are studying how energy gets converted in superheated plasmas in space.

Their findings, published in Physical Review Letters, will revamp scientists’ understanding of how plasmas in space and laboratories get heated up, and may have a wide variety of further applications across physics and other sciences.

John Vervaeke and Donald Hoffman talk about infinity, ego, death, non-dualism, and what is reality. Sponsors:
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Continue reading “Hoffman Λ Vervaeke: Redefining Reality” »

Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.

The findings published in the journal Cellular and Molecular Gastroenterology and Hepatology (CMGH) reveal that psyllium, which is semi-soluble and derived from Plantago seeds, inhibits inflammation that can lead to colitis in mice by increasing serum bile acids, resulting in the activation of the farnesoid X receptor (FXR), a bile acid nuclear receptor.

Fiber-rich foods promote intestinal and metabolic health, but the extent of protection varies for each fiber type and the mechanisms that offer this protection are poorly defined. It has been unclear whether dietary fiber can benefit severe forms of intestinal inflammation, such as Crohn’s disease and ulcerative colitis, which are collectively known as inflammatory bowel disease (IBD) and affect 3 million adults in the United States.

A million here, times a million there. Pretty soon you’re talking about big numbers. So Nvidia claims for its AI accelerating hardware in terms of the performance boost it has delivered over the last decade and will deliver again over the next 10 years.

The result, if Nvidia is correct, will be a new industry of AI factories across the world and gigantic breakthroughs in AI processing power. It also means, ostensibly, AI models one million times more powerful than existing examples, including ChatGPT, in AI processing terms at least.

Bits of the stars are all around us, and in us, too. About half of the abundance of elements heavier than iron originates in some of the most violent explosions in the cosmos. As the universe churns and new stars and planets form out of old gas and dust, these elements eventually make their way to Earth and other worlds. After 3.7 billion years of evolution on our planet, humans and many other species have come to rely on them in our bodies and our lives. Iodine, for instance, is a component of hormones we need to control our brain development and regulate our metabolism. Ocean microplankton called Acantharea use the element strontium to create intricate mineral skeletons. Gallium is critical for the chips in our smartphones and our laptop screens. And the mirrors of the JWST are gilded with gold, an element useful for its unreactive nature and ability to reflect infrared light (not to mention its popularity in jewelry).

Scientists have long had a basic idea of how these elements come to be, but for many years the details were hazy and fiercely debated. That changed recently when astronomers observed, for the first time, heavy-element synthesis in action. The process, the evidence suggests, went something like this.

Continue reading “How Star Collisions Forge the Universe’s Heaviest Elements” »