Lifeboat Foundation

Hey folks, I’m excited to share a new essay with y’all on my proposed route towards nanoscale human brain connectomics. I suggest that synchrotron ‘expansion x-ray microscopy’ has the potential to enable anatomical imaging of the entire human brain with sub-100 nm voxel size and high contrast in around 1 year for a price of roughly $10M. I plan to continue improving this essay over time as I acquire more detailed information and perform more calculations.

For a brief history of this concept: I started exploring this idea during undergrad (working with a laboratory-scale x-ray microscope), but was cut short by the pandemic. Now, I’m working on a PhD in biomedical engineering centered on gene therapy and synthetic biology, but I have retained a strong interest in connectomics. I recently began communication with some excellent collaborators who might be able to help move this technology forward. Hoping for some exciting progress!

By Logan Thrasher Collins.

Continue reading “Feasibility of mapping the human brain with expansion x-ray microscopy” »

Quantum computers are highly energy-efficient and extremely powerful supercomputers. But for these machines to realize their full potential in new applications like artificial intelligence or machine learning, researchers are hard at work at perfecting the underlying electronics to process their calculations. A team at Fraunhofer IZM are working on superconducting connections that measure a mere ten micrometers in thickness, moving the industry a substantial step closer to a future of commercially viable quantum computers.

With the extreme computing power they promise, quantum computers have the potential to become the driving force for technological innovations in all areas of modern industry. By contrast with the run-of-the-mill computers of today, they do not work with bits, but with qubits: No longer are these units of information restricted to the binary states of 1 or 0.

With quantum superposition or entanglement added, qubits mean a great leap forward in terms of sheer speed and power and the complexity of the calculations they can handle. One simple rule still holds, though: More qubits mean more speed and more computing power.

Step one for uploading your brain after the singularity… keep it cognitively functional until then.

It’s been estimated that one in three cases of dementia is preventable. You can’t do anything right now to stop or reverse the underlying mechanisms of Alzheimer’s disease, but you can do something about hypertension and vascular disease risk factors.

Continue reading “Can I Prevent Dementia?” »

Materials research organizations in Asia have been targeted by a previously unknown threat actor using a distinct set of tools.

Symantec, by Broadcom Software, is tracking the cluster under the moniker Clasiopa. The origins of the hacking group and its affiliations are currently unknown, but there are hints that suggest the adversary could have ties to India.

This includes references to “SAPTARISHI-ATHARVAN-101” in a custom backdoor and the use of the password “iloveindea1998^_^” for a ZIP archive.

In this video we run through a recent study which analyzed data in the UK Biobank to see if patients taking lithium as an anti-psychotic saw extended lifespan of those using a different type of medication and they found that they did.

📃Papers in this video.
Lithium treatment extends human lifespan: findings from the UK Biobank.
_https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925675/_
Low-dose lithium uptake promotes longevity in humans and metazoans.
_https://pubmed.ncbi.nlm.nih.gov/21301855/_

Continue reading “Lithium Extends Human Lifespan In Two Studies” »

José Cordeiro is convinced that victory over death is only a matter of time. He believes people will soon be able to choose the age at which they want to live.

José Cordeiro, living forever has been a dream of human beings since their beginning. Currently, we live for around 100 years, whales and turtles live even longer. Is that fair?

In the physical world, time marches in one direction, but things aren’t so straight forward in the quantum realm. Researchers have discovered that it’s possible to speed up, slow down, or reverse the flow of time in a quantum system. This isn’t exactly time travel, but is instead implementing or reverting to different quantum states from different points in time.

Sensing a hug from each other via the internet may be a possibility in the near future. A research team led by City University of Hong Kong (CityU) recently developed a wireless, soft e-skin that can both detect and deliver the sense of touch, and form a touch network allowing one-to-multiuser interaction. It offers great potential for enhancing the immersion of distance touch communication.

“With the rapid development of virtual and augmented reality (VR and AR), our visual and auditory senses are not sufficient for us to create an immersive experience. Touch communication could be a revolution for us to interact throughout the metaverse,” said Dr. Yu Xinge, Associate Professor in the Department of Biomedical Engineering (BME) at CityU.

While there are numerous haptic interfaces in the market to simulate tactile sensation in the virtual world, they provide only touch sensing or haptic feedback. The uniqueness of the novel e-skin is that it can perform self-sensing and haptic reproducing functions on the same interface.

Scientists at the University of Massachusetts Amherst recently announced the invention of a nanowire, 10,000 times thinner than a human hair, which can be cheaply grown by common bacteria and can be tuned to “smell” a vast array of chemical tracers—including those given off by people afflicted with different medical conditions, such as asthma and kidney disease.

Thousands of these specially tuned wires, each sniffing out a different chemical, can be layered onto tiny, wearable sensors, allowing health-care providers an unprecedented tool for monitoring potential health complications. Since these wires are grown by bacteria, they are organic, biodegradable and far greener than any inorganic nanowire.

To make these breakthroughs, which were detailed in the journal Biosensors and Bioelectrics, senior authors Derek Lovley, Distinguished Professor of Microbiology at UMass Amherst, and Jun Yao, professor of electrical and computer engineering in the College of Engineering at UMass Amherst, needed to look no farther than their own noses.