Lifeboat Foundation

Bruce Willis has FTD. I always wondered if gene therapy could help. Apparently so did Passage Bio, and they are doing clinical trials.

FTD is a disorder that affects the frontal and temporal lobes of the brain, areas that control personality, executive function, and language. FTD is a form of early onset dementia and currently has no approved disease-modifying therapies. In approximately 5–10% of individuals with FTD, the disease occurs because of mutations in the GRN gene. These mutations cause a deficiency of progranulin that helps regulate cellular processes.

Continue reading “Gene Therapy Clinical Trial for Frontotemporal Dementia Has Begun” »

Tunneling reactions in chemistry are difficult to predict. The quantum mechanically exact description of chemical reactions with more than three particles is difficult, with more than four particles it is almost impossible. Theorists simulate these reactions with classical physics and must neglect quantum effects. But where is the limit of this classical description of chemical reactions, which can only provide approximations?

Roland Wester from the Department of Ion Physics and Applied Physics at the University of Innsbruck has long wanted to explore this frontier. “It requires an experiment that allows very precise measurements and can still be described quantum-mechanically,” says the experimental physicist. “The idea came to me 15 years ago in a conversation with a colleague at a conference in the U.S.,” Wester recalls. He wanted to trace the quantum mechanical tunnel effect in a very simple reaction.

Since the tunnel effect makes the reaction very unlikely and thus slow, its experimental observation was extraordinarily difficult. After several attempts, however, Wester’s team has now succeeded in doing just that for the first time, as they report in the current issue of the journal Nature.

Nvidia has released a new driver update enabling support for Video Super Resolution, which uses AI to improve the quality of most online videos.

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Continue reading “LEAKED: Elon’s Secret AI Lab, Tesla Mexico, Toyota Doomed” »

Thinks he now has the answer to time travel — but you thankfully won’t be needing a DeLorean like the hit 8’0s movie Back to the Future A scientist believes he has finally cracked the code to enable time travel after having a big ‘eureka’ moment as he lay in hospital.

A team of scientists, including physicist Eugene Demler from ETH Zurich, for the first time, closely observed how magnetic correlations play a role in mediating hole pairing.

Superconductivity only occurs in pairs. Therefore, in order for conductance without electrical resistance to take place in specific materials, the charge carriers must pair up. In traditional superconductors, the current is made up of electrons and pairing is facilitated by the collective movements of the crystal lattice, referred to as phonons. This mechanism is well understood. However, in recent decades, a growing number of materials have been found that don’t fit within this conventional theoretical framework.

The leading theories for unconventional superconductors suggest that magnetic fluctuations, not phonons, lead to pairing in these systems, — and surprisingly, magnetic interactions arise from the repulsive Coulomb interaction between electrons. However, verifying these models in experiments is extremely difficult.

An ongoing study led by Cedars-Sinai has demonstrated that certain gut bacteria may increase the risk of Type 2 diabetes while others may provide protection against it. These are early results from a prospective study.

According to the study, which was published in the journal Diabetes, higher levels of the bacterium Coprococcus are associated with improved insulin.

Insulin is a hormone that regulates the level of glucose (sugar) in the blood. It is produced by the pancreas and released into the bloodstream when the level of glucose in the blood rises, such as after a meal. Insulin helps to transport glucose from the bloodstream into the cells, where it can be used for energy or stored for later use. Insulin also helps to regulate the metabolism of fat and protein. In individuals with diabetes, their body doesn’t produce enough insulin or doesn’t respond properly to insulin, leading to high blood sugar levels, which can lead to serious health problems if left untreated.

Will a machine learning AI be the way we find out we are not alone in the Universe?

In a January 2023 published paper in Nature Astronomy, a collaboration by authors from universities in Toronto, Canada, Berkeley in California, Manchester in the United Kingdom, Malta, Queensland and Western Australia, and the SETI Institute, created a machine learning algorithm variational autoencoder, a type of neural network that learns through the unsupervised study of unlabelled data. They used it to try and find technosignatures contained within 150 Terabytes of radio traffic from 820 nearby stars. The data source came from the Green Bank Telescope in West Virginia, the world’s largest steerable radio telescope. This data had previously been searched in 2017 using traditional techniques.

Radio signals are abundant throughout the Universe and they represent the most effective way for us to find out if we are a solo act or one of many technical civilizations. Our contribution to radio traffic has been going on for more than a century which means an alien civilization within a hundred light-years from us with technology similar to ours can now detect us.

Continue reading “Will AI Make First Contact with Extra-Terrestrial Intelligence?” »

Over 1 million researchers have used the AI breakthrough that helps scientists better understand diseases. Here’s how AlphaFold came to be.