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The virus found in these regions is derived from an oral polio vaccine used in some countries. So far, only two cases of polio-related paralysis have been reported, in Jerusalem in February and New York in June¹; the New York infection was the first such US case in nearly a decade. But wastewater samples in all three areas suggest that the virus is circulating more widely.

Polio causes irreversible paralysis in less than one in 200 of the susceptible people it infects, so the cases of paralysis suggest that many other people there have been infected, says Walter Orenstein, who studies infectious diseases at Emory University in Atlanta, Georgia. “Cases like that are just the tip of the iceberg,” he says. “It’s very concerning.”

Nature talked to researchers about the scale of the outbreak, and what can be done to stop it.

Klunk and colleagues identify signatures of natural selection imposed by Yersinia pestis and demonstrate their effect on genetic diversity and susceptibility to certain diseases in the present day.

This could give more immunity to viruses with the gene they found helped people survive the black death.

“We all think that COVID-19 was insane and completely changed the world and our societies,” Barreiro says. “COVID has a mortality rate of about 0.05% – something like that. Now try to project – if it’s even possible – a scenario where 30 to 50% of the population dies.”

Now a new study, published Wednesday in the journal Nature, shows that the Black Death altered more than society: It also likely altered the evolution of the European people’s genome.

Continue reading “Black Death survivors gave their descendants a genetic advantage — but with a cost” »

COURTS across the globe are braced for a surge in cases related to AI in years to come as the technology develops at a rapid pace.

Officials are scrambling to come up with new laws on how the advanced systems should be kept in check and ultimately who is responsible for what they do or create.

We recently heard about AI-generated art that won a competition in Colorado, leading to a backlash and questions about fairness.

Contact electrification (CE) was humanity’s earliest and sole source of electricity until about the 18th century, but its real nature remains a mystery. Today, it is regarded as a critical component of technologies such as laser printers, LCD production processes, electrostatic painting, plastic separation for recycling, and more, as well as a major industrial hazard (damage to electronic systems, explosions in coal mines, fires in chemical plants) due to the electrostatic discharges (ESD) that accompany CE. A 2008 study published in Nature found that in a vacuum, ESDs of a simple adhesive tape are so powerful that they generate enough X-rays to take an X-ray image of a finger.

For a long time, it was believed that two contacting/sliding materials charge in opposing and uniform directions. However, after CE, it was discovered that each of the separated surfaces carries both (+) and (-) charges. The formation of so-called charge mosaics was attributed to experiment irreproducibility, inherent inhomogeneities of contacting materials, or the general “stochastic nature” of CE.

Researchers from Australia and Singapore are working on a new quantum technique that could enhance optical VLBI. It’s known as Stimulated Raman Adiabatic Passage (STIRAP), which allows quantum information to be transferred without losses. When imprinted into a quantum error correction code, this technique could allow for VLBI observations into previously inaccessible wavelengths. Once integrated with next-generation instruments, this technique could allow for more detailed studies of black holes, exoplanets, the Solar System, and the surfaces of distant stars.

The interferometry technique consists of combining light from multiple telescopes to create images of an object that would otherwise be too difficult to resolve. Very Long Baseline Interferometry refers to a specific technique used in radio astronomy where signals from an astronomical radio source (black holes, quasars, pulsars, star-forming nebulae, etc.) are combined to create detailed images of their structure and activity. In recent years, VLBI has yielded the most detailed images of the stars that orbit Sagitarrius A* (Sgr A•, the SMBH at the center of our galaxy.

Summary: Researchers have identified a new type of synaptic plasticity they call behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex sends instructive signals to the hippocampus and directs it to specifically reorganize the specific location and activity of a neural subset to achieve altered behavior in response to changes in environment and spatial cues.

Source: Texas Children’s Hospital.

A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences.

Rotary molecular motors were first created in 1999, in the laboratory of Ben Feringa, Professor of Organic Chemistry at the University of Groningen. These motors are driven by light. For many reasons, it would be good to be able to make these motor molecules visible. The best way to do this is to make them fluoresce. However, combining two light-mediated functions in a single molecule is quite challenging. The Feringa laboratory has now succeeded in doing just that, in two different ways. These two types of fluorescing light-driven rotary motors were described in Nature Communications (September 30) and Science Advances (November 4).

“After the successful design of molecular motors in the past decades, an important next goal was to control various functions and properties using such motors,” explains Feringa, who shared in the Nobel Prize in Chemistry in 2016. “As these are light-powered rotary motors, it is particularly challenging to design a system that would have another function that is controlled by light energy, in addition to the rotary motion.”

Feringa and his team were particularly interested in fluorescence since this is a prime technique that is widely used for detection, for example in biomedical imaging. Usually, two such photochemical events are incompatible in the same molecule; either the light-driven motor operates and there is no fluorescence or there is fluorescence and the motor does not operate. Feringa says, “We have now demonstrated that both functions can exist in parallel in the same molecular system, which is rather unique.”

A new study from the University of Central Florida has found strong support that the outgassing of molecules from comets could be the result of the composition from the beginning of our solar system.

The results were published today in The Planetary Science Journal.

The study was led by Olga Harrington Pinto, a doctoral candidate in UCF’s Department of Physics, part of the College of Sciences.