Lifeboat Foundation

Social behavior (SB) is a fundamental hallmark of human interaction. Repeated administration of low doses of the 5-HT2A agonist lysergic acid diethylamide (LSD) in mice enhances SB by potentiating 5-HT2A and AMPA receptor neurotransmission in the mPFC via an increasing phosphorylation of the mTORC1, a protein involved in the modulation of SB. Moreover, the inactivation of mPFC glutamate neurotransmission impairs SB and nullifies the prosocial effects of LSD. Finally, LSD requires the integrity of mTORC1 in excitatory glutamatergic, but not in inhibitory neurons, to produce prosocial effects. This study unveils a mechanism contributing to the role of 5-HT2A agonism in the modulation of SB.

All study data are included in the article and supporting information.

Building a corn cob—cell by cell, gene by gene.

Corn hasn’t always been the sweet, juicy delight that we know today. And, without adapting to a rapidly changing climate, it is at risk of losing its place as a food staple. Putting together a plant is a genetic puzzle, with hundreds of genes working together as it grows. Cold Spring Harbor Laboratory (CSHL) Professor David Jackson worked with Associate Professor Jesse Gillis to study genes involved in corn development. Their teams analyzed thousands of individual cells that make up the developing corn ear. They created the first anatomical map that shows where and when important genes turn on and off during key steps in development. This map is an important tool for growing better crops.

COVID-19 may have shocked the city’s commercial market but that hasn’t stopped developers from doing what they do best. In fact, a bevy of newly constructed and redeveloped towers are poised to hit the market in Manhattan.

Industry experts told The Post that it will be those new buildings, designed with cutting-edge tech and with future pandemics in mind, that will have the greatest advantage on the market.

“There is no question the buildings provisioned for the 21st century-plus are going to be in a better position to cash in on the leasing opportunities ahead,” said David Goldstein, vice chairman of real estate services provider Savills. “It could be an older building reimagined, or a new one under construction or in planning stages.”

Non-profit Food Plant Solutions represents five decades of work by agricultural scientist Bruce French to catalogue more than 31000 edible plants so children do not have to go hungry.

Defiant X can fly twice as far and fast as the greatest helo ever.

The Lockheed Martin-owned Sikorsky and Boeing have rolled out the final specs of their new helicopter, one of two candidates that will replace the U.S. Army’s iconic UH-60 Black Hawk. The Defiant X isn’t just meant to replace the Black Hawk, but also fly up to twice as fast and twice as far, giving Army air assault forces an unparalleled battlefield mobility.

Continue reading “Here’s the Truly Beastly Helicopter That Might Replace the Black Hawk” »

Micro-sized robots could bring a new wave of innovation in the medical field by allowing doctors to access specific regions inside the human body without the need for highly invasive procedures. Among other things, these tiny robots could be used to carry drugs, genes or other substances to specific sites inside the body, opening up new possibilities for treating different medical conditions.

Researchers at ETH Zurich and Helmholtz Institute Erlangen–Nürnberg for Renewable Energy have recently developed micro and nano-sized robots inspired by biological micro-swimmers (e.g., bacteria or spermatozoa). These small robots, presented in a paper published in Nature Machine Intelligence, are capable of upstream motility, which essentially means that they can autonomously move in the opposite direction to that in which a fluid (e.g., blood) flows. This makes them particularly promising for intervening inside the human body.

“We believe that the ideas discussed in our multidisciplinary study can transform many aspects of medicine by enabling tasks such as targeted and precise delivery of drugs or genes, as well as facilitating non-invasive surgeries,” Daniel Ahmed, lead author of the recent paper, told TechXplore.

A new research paper suggests AI practitioners adopt anthropology terms to assess large machine learning models that harm people.