Lifeboat Foundation

As I look back on the year, I am also thinking about the specific areas I work on. Some of this is done through our foundation but a lot of it (such as my work on energy and Alzheimer’s work) is not. What connects it all is my belief that innovation can save lives and improve everyone’s well-being. A lot of people underestimate just how much innovation will make life better.

Here are a few updates on what’s going well and what isn’t with innovation in some areas where I work.

Bill Gates looks back on 2018, and shares a few thoughts on what’s going well and what isn’t with innovation in some specific areas that he works on.

Buck researchers also harness an innate repair mechanism to protect against liver damage in aging mice and extend lifespan in flies.

Manufacturers will have to make appliances, like TVs and washing machines, last longer and easier to mend.

A machine which triples the time livers can survive outside the body promises to halve the transplant waiting list, experts have said as officials approved its use in the NHS.

Hundreds more patients with advanced liver disease — Britain’s fifth biggest killer — have hope of a successful transplant after the “game-changing” technique was given the green light by the National Institute of Health and Care Excellence (Nice).

Currently livers intended for transplant typically survive for only about eight to ten hours on ice.

Continue reading “Liver transplant breakthrough to halve the waiting list, say experts” »

Researchers with the University of Michigan have developed a new 3D printing technology that is capable of printing 100 times faster than normal 3D printers. Unlike traditional 3D printers, which work by applying plastic down as layers, the new technology involves resin that is solidified upward at rapid speeds. The new method is capable of producing complex objects at speeds that traditional printers can’t compete with.

New research published in the journal Nature Medicine has described the results of a five-year study into the association between a breakdown of the blood-brain barrier and the onset of cognitive impairment. The study suggests leaky capillaries in the brain can act as an early biomarker of cognitive decline, and a new drug being developed for stroke patients may be an effective treatment.

The production of entropy, which means increasing the degree of disorder in a system, is an inexorable tendency in the macroscopic world owing to the second law of thermodynamics. This makes the processes described by classical physics irreversible and, by extension, imposes a direction on the flow of time. However, the tendency does not necessarily apply in the microscopic world, which is governed by quantum mechanics. The laws of quantum physics are reversible in time, so in the microscopic world, there is no preferential direction to the flow of phenomena.

One of the most important aims of contemporary scientific research is knowing exactly where the transition occurs from the quantum world to the classical world and why it occurs — in other words, finding out what makes the production of entropy predominate. This aim explains the current interest in studying mesoscopic systems, which are not as small as individual atoms but nevertheless display well-defined quantum behavior.

Freud’s notion of a dark, libidinous unconscious is obsolete. A new theory holds that the brain produces a continuous stream of unconscious predictions.

• By Steve Ayan on December 19, 2018

A scientific collaboration has released a concept design for the Large Hadron Collider’s successor, an enormous new experiment that would sit inside a hundred-kilometer (62-mile) tunnel.

The design concept plans for two Future Circular Colliders, the first which would begin operation perhaps in 2040. The ambitious experiments would hunt for new particles with collision energies 10 times higher than those created by the Large Hadron Collider (LHC). The concept design is the first big milestone achieved by the scientific collaboration.