Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.
A reduction in blood flow to the brain caused by stroke is a major cause of death and disability, and there are few effective treatments.
A team of scientists at The University of Manchester has now found that a potential new stroke drug not only works in rodents by limiting the death of existing brain cells but also by promoting the birth of new neurones (so-called neurogenesis).
For many years, scientists believed that our brains were unable to produce new neurons once we had been born, and that we all had to make do with the brain cells we started life with. Later, it became clear that new brain cells are in fact created in some key brain regions, replacing those that become damaged and protecting us from dementia. Now, researchers have discovered that the stem cells giving rise to these neurons originate in the membranes encasing the brain, known as the meninges.
Publishing their findings in the journal Cell Stem Cell, the authors claim that their discovery of this source of stem cells could one day lead to new treatments for brain damage or neurodegenerative disorders.
Most neurogenesis in the adult brain occurs in a region called the hippocampus, where the creation of new brain cells ensures our memories remain in working order as we age. The meninges penetrate the brain at every level, encapsulating a number of different regions, including the hippocampus.
PHILADELPHIA (CBS) — All the years of your parents saying “NO” to ice cream for breakfast may have actually stunted your brilliance.
According to The Telegraph, a new study performed by Yoshihiko Koga, a professor at Kyorin University in Tokyo, revealed that eating a certain amount of ice cream immediately after waking up in the morning can actually make you smarter.
Our brains have a basic algorithm that enables us to not just recognize a traditional Thanksgiving meal, but the intelligence to ponder the broader implications of a bountiful harvest as well as good family and friends.
“A relatively simple mathematical logic underlies our complex brain computations,” said Dr. Joe Z. Tsien, neuroscientist at the Medical College of Georgia at Augusta University, co-director of the Augusta University Brain and Behavior Discovery Institute and Georgia Research Alliance Eminent Scholar in Cognitive and Systems Neurobiology.
In a cross-domain study directed by professor Peter Carmeliet (VIB — KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges. These ‘neural progenitors’ — or stem cells that differentiate into different kinds of neurons — are produced during embryonic development. These findings show that the neural progenitors found in the meninges produce new neurons after birth — highlighting the importance of meningeal tissue as well as these cells’ potential in the development of new therapies for brain damage or neurodegeneration. A paper highlighting the results was published in the leading scientific journal Cell Stem Cell.
Scientists’ understanding of brain plasticity, or the ability of the brain to grow, develop, recover from injuries and adapt to changing conditions throughout our lives, has been greatly broadened in recent years. Before the discoveries of the last few decades, neurologists once thought that the brain became ‘static’ after childhood. This dogma has changed, with researchers finding more and more evidence that the brain is capable of healing and regenerating in adulthood, thanks to the presence of stem cells. However, neuronal stem cells were generally believed to only reside within the brain tissue, not in the membranes surrounding it.
The meninges: unappreciated no more: Believed in the past to serve a mainly protective function to dampen mechanical shocks, the meninges have been historically underappreciated by science as having neurological importance in its own right. The data gathered by the team challenges the current idea that neural precursors — or stem cells that give rise to neurons — can only be found inside actual brain tissue.
BENGALURU: After working for five years, a team of three from department of Biosciences and Bioengineering (BSBE) at Indian Institute of Technology (IIT), Bombay and IITB-Monash Research Academy has designed smart amyloid based hydrogels that are able to guide stem cell to differentiate to neuron and successfully transplanted these stem cells in the brain of Parkinson’s disease (PD) animal models with unique amyloid hydrogels.
DARPA sees a real possibility for spaced based conflict. So, it’s hoping to create breakthrough technology to dissuade U.S. adversaries who might consider attacking from space.
Defense Advanced Research Projects Agency assists national security with efforts in space. It focuses on making space a “real-time operational domain,” as DARPA Director Dr. Arati Prabhakar recently said.
“The questions we ask ourselves at DARPA about the space domain … is what would it take to make the space domain robust for everything that we need militarily and for intelligence, and what would it take to make space a real-time operational domain, which it’s not at all today,” the director said last week at the 4th annual Defense One Summit. Many nation-states now orbit the Earth. Conflict is a real possibility, believes Prabhakar.
The mere mention of “quantum consciousness” makes most physicists cringe, as the phrase seems to evoke the vague, insipid musings of a New Age guru. But if a new hypothesis proves to be correct, quantum effects might indeed play some role in human cognition. Matthew Fisher, a physicist at the University of California, Santa Barbara, raised eyebrows late last year when he published a paper in Annals of Physics proposing that the nuclear spins of phosphorus atoms could serve as rudimentary “qubits” in the brain — which would essentially enable the brain to function like a quantum computer.
Isher’s hypothesis faces the same daunting obstacle that has plagued microtubules: a phenomenon called quantum decoherence. To build an operating quantum computer, you need to connect qubits — quantum bits of information — in a process called entanglement. But entangled qubits exist in a fragile state. They must be carefully shielded from any noise in the surrounding environment. Just one photon bumping into your qubit would be enough to make the entire system “decohere,” destroying the entanglement and wiping out the quantum properties of the system. It’s challenging enough to do quantum processing in a carefully controlled laboratory environment, never mind the warm, wet, complicated mess that is human biology, where maintaining coherence for sufficiently long periods of time is well nigh impossible.
Over the past decade, however, growing evidence suggests that certain biological systems might employ quantum mechanics. In photosynthesis, for example, quantum effects help plants turn sunlight into fuel. Scientists have also proposed that migratory birds have a “quantum compass” enabling them to exploit Earth’s magnetic fields for navigation, or that the human sense of smell could be rooted in quantum mechanics.