Lifeboat Foundation

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

Dr Anne Hahn and Associate Professor Steven Zuryn from UQ’s Queensland Brain Institute said the findings could provide a promising therapeutic avenue to stop the onset of heritable and age-related diseases.

“Mitochondrial DNA is essential for cell function,” Dr Hahn said.

For generations, humans have tried to find the elixir which can extend their lives beyond their natural limit and deceive death.

Now, scientists have made a discovery of a gene which has brought humanity very close to this impossible target of achieving longevity.

The gene has been found to possess the capability of promoting cellular repair and reducing the effects of ageing. This discovery has taken the scientific community close to finding methods for extending not just long but healthy lives.

Summary: New research in mice reveals that aging slows the brain’s ability to clear out harmful waste, contributing to neurological disorders like Alzheimer’s and Parkinson’s. Scientists have found that restoring function in the brain’s waste-clearing system, known as the glymphatic system, can reverse these age-related effects.

Using a clinically approved drug, researchers increased the efficiency of waste removal, offering a potential treatment strategy for age-related brain diseases.

The new research harnesses previously unknown features of this ancient viral DNA, creating a biological clock to track a person’s age from the DNA’s chemical changes.

And the researchers now believe that new antiretroviral therapies, similar to those used to fight the HIV virus and AIDS, might one day help reverse the signs of aging.

‘Our findings indicate that retroelement clocks capture previously undetected facets of biological aging,’ said study co-author Dr Michael Corley, an assistant professor of immunology at Weill Cornell Medicine in New York.

Researchers have discovered cells in a sea anemone that might explain its potential immortality. These cells, regulated by ancient genes, offer insights into regeneration and aging processes that could illuminate human health and longevity.

The study reveals how these genes, active in humans for forming reproductive cells, also confer regenerative abilities on cnidarians, a group of animals including sea anemones.

Discovering Immortality in Sea Anemones.

This creature can regress to the larval stage. Sometimes better start from the beginning 😉

Meet the tiny, gelatinous animal that has found a way to live forever.

Not in leading research but interesting.

According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1].

Traditional and folk medicines offer many botanical extracts that can be tested by modern science for their medicinal properties and influences on aging. One such plant is the Bolivian prawn sage (Salvia haenkei).

Continue reading “A Botanical Extract Extends Lifespan and Healthspan in Mice” »

The Longevity Biotech Fellowship is a non-profit community for people to come together to build, join, or invest in revolutionary longevity biotechnology projects. The Fellowship was founded in 2022 by Nathan Cheng, Mark Hamalainen, and Jun Axup as part of LessDeath Inc— an IRS-approved 501©3 non-profit based in California.

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