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Mar 19, 2024

Age-related changes in fibroblast cells promote pancreatic cancer growth and spread

Posted by in categories: biotech/medical, life extension

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

The study, published online Feb. 8 in Cancer Research, provides clues as to why pancreatic cancer is more common and aggressive in older people. It may also help scientists develop new therapeutic approaches for this difficult-to-treat cancer. The study showed that aging alters fibroblasts in ways that enable them to promote pancreatic cancer tumor growth.

“Older fibroblasts release proteins that directly affect pancreatic cancer cells and ultimately lead to the growth and spread of pancreatic cancer tumors,” says the study’s lead author, Daniel Zabransky, M.D., Ph.D., assistant professor of oncology at the Johns Hopkins University School of Medicine. “The younger fibroblasts did not have these capabilities. We think this is a key reason why we see pancreatic cancer more commonly in older patients.”

Mar 19, 2024

New algorithm unlocks high-resolution insights for computer vision

Posted by in categories: information science, robotics/AI

MIT CSAIL researchers introduce FeatUp, a model-agnostic framework designed to significantly enhance the spatial resolution of deep learning features for improved performance in computer vision tasks such as semantic segmentation, depth prediction, and object detection.

Mar 19, 2024

SpaceX Starship IFT3 Aftermath: New Insights Paint Different Picture!

Posted by in category: space travel

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Continue reading “SpaceX Starship IFT3 Aftermath: New Insights Paint Different Picture!” »

Mar 19, 2024

Nvidia’s Next-Gen AI Chip Is a 1,000W GPU: Dell Exec

Posted by in category: robotics/AI

According to Nvidia’s roadmap, it’ll unveil its next-gen Blackwell architecture soon. The company always launches a new architecture with data center products first and then reveals the cut-down GeForce versions many months later, so that’s what’s expected this time as well. On that note, the company’s semi-annual GTC technology conference starts in two weeks, so we expect a lot to be revealed at the show. As proof that Nvidia is close to pulling the wraps off its new data center GPUs, a Dell executive has already shared some juicy info about next-gen Nvidia hardware, saying in a recent earnings call the company has a 1,000W data center GPU in the pipeline.

The executive who has probably already received an angry call from Jensen is Jeff Clarke, a COO at Dell. On a Feb. 29 earnings call (PDF), the executive discussed Dell’s engineering superiority and how upcoming hardware from Nvidia will give the company a chance to show it off. “We’re excited about what happens at the B100 and the B200,” he said, which are the die names for Nvidia’s next-generation data center GPU and its apparent successor. For context, Nvidia currently has the H100 as its flagship data center GPU and is just now launching the second iteration with faster HBM3e memory, dubbed H200. We all know the B100 is the Blackwell successor to this chip, so it appears the B200 will be that GPU’s second iteration, though it does not currently appear on Nvidia’s roadmap (below).

Mar 19, 2024

2022 Ford F-150 Lightning Owner Drove Almost 100,000 Miles. Battery Health Is 97%

Posted by in categories: climatology, health

It’s hard to imagine that a Ford F-150 Lightning out there already has nearly 100,000 miles on its odometer. Especially since they’ve only been on the roads since late May of 2022. That’s less than two years ago, yet here we have a Ford F-150 Lightning owner reporting on his electric truck with 93,000 miles on the odometer.

He’s owned this F-150 Lightning for 21 months now, so that works out to an average of 4,429 miles driven per month or about 53,000 miles yearly. And while that’s certainly a lot of driving, what’s perhaps most interesting is the battery health of the electric pickup truck.

Mar 19, 2024

Microsoft Forms New AI Division to Push Copilot to Consumers

Posted by in category: robotics/AI

He then left Google and started a new AI lab called Inflection AI, which he ran as CEO. He and Inflection’s chief scientist, Karén Simonyan, are now jumping ship to help lead Microsoft AI.

Suleyman will become both a Microsoft EVP and run the new Microsoft AI group as CEO. On why he was selected, Nadella said: “I’ve known Mustafa for several years and have greatly admired him as a founder of both DeepMind and Inflection, and as a visionary, product maker, and builder of pioneering teams that go after bold missions.”

Meanwhile, Suleyman noted in a LinkedIn post: “I’ll be leading all consumer AI products and research, including Copilot, Bing and Edge.” Several of his co-workers at Inflection have also decided to migrate to Microsoft, he wrote.

Mar 19, 2024

Caffeine makes fuel cells more efficient, cuts energy cost

Posted by in category: energy

Boffins show less platinum may be needed for long-lived power source.

Mar 19, 2024

‘Sound laser’ is the most powerful ever made

Posted by in category: particle physics

A new device uses a reflective cavity, a tiny bead and an electrode to create a laser beam of sound particles ten times more powerful and much narrower than other “phonon lasers”

Mar 19, 2024

NIO Switches Its Standard 75-kWh Battery From Hybrid-Cell LFP/NCM To All-LFP

Posted by in categories: chemistry, transportation

NIO’s entry-level Standard battery pack option will soon get an upgrade with the new 2024 model year cars.

According to the company (via CnEVPost), the 75-kilowatt-hour dual-chemistry (LFP/NCM) Standard battery will be replaced by a new 75-kWh battery with only LFP battery cells. This should simplify the pack and reduce costs. LFP’s battery cell chemistry is known as one of the least expensive per kWh.

Mar 19, 2024

The mass-energy-information equivalence principle

Posted by in category: computing

Landauer’s principle formulated in 1961 states that logical irreversibility implies physical irreversibility and demonstrated that information is physical. Here we formulate a new principle of mass-energy-information equivalence proposing that a bit of information is not just physical, as already demonstrated, but it has a finite and quantifiable mass while it stores information. In this framework, it is shown that the mass of a bit of information at room temperature (300K) is 3.19 × 10-38 Kg. To test the hypothesis we propose here an experiment, predicting that the mass of a data storage device would increase by a small amount when is full of digital information relative to its mass in erased state. For 1Tb device the estimated mass change is 2.5 × 10-25 Kg.

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