Lifeboat Foundation

While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or “healthspan,” that precedes the inevitable decline of advancing age. Researchers at UC Santa Barbara have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.

Mitochondria generate the energy for all of our activities, from movement to thought. These power plants inside our cells descended from what were once free-living bacteria.

“We are a sort of hybrid creature that arose from two independent evolutionary lineages: mitochondria, which were once bacteria, and the rest of the cell surrounding them,” notes Joel Rothman, a professor of molecular biology whose lab conducted the research.

Whether talking about the office kitchen, hiking trails or ratings on Yelp, there are always people who put in effort to leave those spaces better. There are also those who contribute nothing to that public good.

New research using large-scale online experiments suggests that rewarding people to contribute to a virtual public good, such as a simulated online rating for a ferry system, increased the accuracy of the ratings and improved the overall quality of that resource.

The multidisciplinary team, including researchers from the University of California, Davis; Hunter College, College of New York; the Max Planck Institute for Empirical Aesthetics; and Princeton University tested ideas about collective action in a simulation incorporating more than 500 people worldwide. Team expertise included communication science, sociology, computer science, psychology and animal behavior.

For more than 50 years, the semiconductor industry has been hard at work developing advanced technologies that have led to the amazing increases in computing power and energy efficiency that have improved our lives. A primary way the industry has achieved these remarkable performance gains has been by finding ways to decrease the size of the semiconductor devices in microchips. However, with semiconductor feature sizes now approaching only a few nanometers—just a few hundred atoms—it has become increasingly challenging to sustain continued device miniaturization.

To address the challenges associated with fabricating even smaller microchip components, the semiconductor industry is currently transitioning to a more powerful fabrication method—extreme ultraviolet (EUV) lithography. EUV lithography employs light that is only 13.5 nanometers in wavelength to form tiny circuit patterns in a photoresist, the light-sensitive material integral to the lithography process.

The photoresist is the template for forming the nanoscale circuit patterns in the silicon semiconductor. As EUV lithography begins paving the way for the future, scientists are faced with the hurdle of identifying the most effective resist materials for this new era of nanofabrication.

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Continue reading “The Kynurenine/Tryptophan Ratio: An Integrated Measure Of Many Pro- And Anti-Inflammatory Factors” »

Agi, if you can see or hear this. WE Eagerly Await and Welcome Your Arrival!!!

Update from November 9, 2023:

During a Q&A session at OpenAI’s developer conference, Altman reiterated that GPT-5 is not yet concrete. OpenAI still has “a lot” of things to figure out before it can train a model it calls GPT-5, Altman said.

Continue reading “OpenAI’s Altman says today’s AI will be ‘quaint’ by next year, talks GPT-5” »

Boston Dynamics Starting from the technological building blocks of Atlas, Stretch has the mobility, power, and intelligence to automate warehousing’s toughest tasks. See how we went from initial idea to a product delivering value in the real world.

A combined team of biomedical researchers from Novartis Institutes for Biomedical Research and Microsoft Research AI4Science has made inroads into teaching AI systems how to find new medicines. In their study, reported in the journal Nature Communications, the group used feedback from chemists in the field to provide intuition guidelines for an AI model.

Finding new medicines is a notoriously difficult and laborious task. The process for finding new therapies typically involves experts in a variety of fields working on different parts of the problem. Doctors and other medical researchers, for example, must first uncover the roots of a given illness to find its cause. Chemists or other medical researchers must then find a chemical that might reverse the problem or stop it from happening in the first place.

Both parts of the process take time and effort. In this new project, the research team sought to determine whether AI applications might make the second part easier.

When you think of empty space, you almost certainly imagine a vacuum in which nothing interesting can ever happen. However, if we zoom in to tiny length scales where quantum effects start to become important, it turns out that what you thought was empty is actually filled at all times with a seething mass of electromagnetic activity, as virtual photons flicker in and out of existence. This unexpected phenomenon is known as the vacuum fluctuation field. However, because these fluctuations of light energy are so small and fleeting in time, it is difficult to find ways for matter to interact with them, especially within a single, integrated device.

In a study published this month in Nano Letters (“Electrical Detection of Ultrastrong Coherent Interaction between Terahertz Fields and Electrons Using Quantum Point Contacts”), researchers from the Institute of Industrial Science, The University of Tokyo succeeded in fabricating a single nanoscale hybrid system for doing exactly this. In their design, a quantum point contact connects a single on-chip split-ring resonator with a two-dimensional electron system.

Quantum Hall edge channels at the quantum point contact. (Image: University of Tokyo)

A method developed at the University of Duisburg-Essen makes it possible to read data from noisy signals. Theoretical physicists and their experimental colleagues have published their findings in the current issue of Physical Review Research. The method they describe could also be significant for quantum computers.

You know it from the car radio: The weaker the signal, the more disturbing the noise. This is even more true for laboratory measurements. Researchers from the Collaborative Research Center 1,242 and the Center for Nanointegration (CENIDE) at the University of Duisburg-Essen (UDE) have now described a method for extracting data from noise.

What is a bit in a conventional computer, i.e., state 1 (current on) or state 0 (current off), is taken over in the quantum computer by the quantum bits, or qubits for short. To do this, they need defined and distinguishable states, but they can overlap at the same time and therefore enable many times the computing power of a current computer. This means they could also be used where today’s supercomputers are overtaxed, for example in searching extremely large databases.