Lifeboat Foundation

The fundamental idea of OpenAI LP is that investors and employees can get a capped return if we succeed at our mission, which allows us to raise investment capital and attract employees with startup-like equity. But any returns beyond that amount—and if we are successful, we expect to generate orders of magnitude more value than we’d owe to people who invest in or work at OpenAI LP—are owned by the original OpenAI Nonprofit entity.

We’ve created OpenAI LP, a new “capped-profit” company that allows us to rapidly increase our investments in compute and talent while including checks and balances to actualize our mission.

A common oral bacteria has been found to release a molecule that accelerates the growth of colorectal cancers. The impressive new research could lead to new cancer treatments as well as offer a valuable biomarker to help doctors identify potentially aggressive cancers.

Scripps Research scientists have discovered a compound that potently and selectively kills the stem-like cells that make glioblastoma brain cancers so deadly.

In a study published this week in The Proceedings of the National Academy of Sciences, the Scripps Research scientists found that the new compound, which they dubbed RIPGBM, kills glioblastoma stem-like cells cultured from patients’ tumors with more than 40 times the potency of the standard GBM drug temozolomide. They found too that RIPGBM is highly selective, sparing other types of brain cells, and that it powerfully suppresses the growth of GBM tumors in a mouse model of the disease.

“Our discovery of this compound and the cellular pathways it affects offers a promising new strategy for treating glioblastoma,” says principal investigator Luke Lairson, PhD, an assistant professor of chemistry at Scripps Research.

Continue reading “Promising compound selectively kills brain cancer stem cells” »

How to keep your assets intact if you’re revived through cryonics.

Traditionally, welding has been limited to materials that share similar properties, so it’s tough to make even aluminum and steel join forces. But now, scientists from Heriot-Watt University are claiming a breakthrough method that can weld together materials as different as glass and metal, thanks to ultrafast laser pulses.

Five years ago, French aeronautical engineer Edwin Van Ruymbeke successfully crowdfunded his Bionic Bird – it’s a remote-control model that flies by flapping its wings, just like a real bird. Now he’s back, with the insect-inspired MetaFly.

The research contradicts a major assumption in physics.

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We could use lasers to conceal the Earth from observation by an advanced extraterrestrial civilization by shining massive laser beams aimed at a specific star where aliens might be located — thus masking our planet during its transit of the Sun, suggest two astronomers at Columbia University in an open-access paper in Monthly Notices of the Royal Astronomical Society.

Continue reading “How to use laser cloaking to hide Earth from remote detection” »

Alzheimer’s disease may soon be spotted through a simple eye test, after scientists discovered tell-tale alterations in the retina and blood vessels when dementia is present.

Currently diagnosing Alzheimer’s is tricky, requiring an expensive brain scan, a risky spinal tap or in most cases a behavioural assessment by a doctor based on symptoms.

But US scientists at the Duke Eye Centre in North Carolina, wondered if changes might also be visible in the retina, which is an extension of the brain and so could offer a window into what is happening behind the skull.

Continue reading “Alzheimer’s disease can be spotted through simple eye test” »