Lifeboat Foundation

Bioelectrical signaling in the African clawed frog modulates both resistance to infection and tail regeneration. Michael Levin at Tufts University in Massachusetts, USA, and colleagues have used genetic technologies and drug treatments to manipulate the bioelectrical properties of tissues in frog embryos. Reducing the electric gradient between the inside and outside of cells (depolarization) increased the embryos’ survival rate to bacterial infection, whereas increasing the resting potential (hyperpolarization) had the opposite effect. The authors found that serotonergic signaling and an increase in the number of myeloid cells underpin depolarization-induced immunity. Interestingly, embryos undergoing tail regeneration, which triggers depolarization, also showed increased resistance to infection.

face_with_colon_three mitochondria immortality.

Researchers at the University of Bayreuth have developed a new method for controlling the growth of physical micro-runners. They used an external magnetic field to assemble paramagnetic colloidal spheres—i.e. only magnetic due to external influences—into rods of a certain length. Colloidal particles are tiny particles in the micro-or nanometer range that can be used in medicine as carriers of biochemicals.

They aren’t clones. They’re xenobots, synthetic lifeforms made from clusters of cells.

Robots such as these, capable of making offshoots of themselves, could be a future tool for science and medicine.

Kidney cancer patients who received an oral probiotic in addition to immunotherapy treatments saw improved outcomes, according to research published in Nature Medicine.

A SEVENTH person has been “cured” of HIV after revolutionary stem cell treatment, it is hoped.

The man, 60, who also had acute myeloid leukaemia when he had the procedure to replace his bone marrow in October 2015, is now thought to be free of both diseases.

Scientists at the University of Sydney have developed a gene-editing tool with greater accuracy and flexibility than the industry standard, CRISPR, which has revolutionized genetic engineering in medicine, agriculture and biotechnology.

SeekRNA uses a programmable ribonucleic acid (RNA) strand that can directly identify sites for insertion in genetic sequences, simplifying the editing process and reducing errors.

The new gene-editing tool is being developed by a team led by Dr. Sandro Ataide in the School of Life and Environmental Sciences. Their findings have been published in Nature Communications.

In a new study, lab mice given an experimental drug were jokingly referred to as “supermodel grannies” because they looked so youthful even while aging beyond their expected lifespan.

As the BBC reports, the trials for a drug believed to flush out a protein known as interleukin-11 — which in early development helps build our bones but later in life causes the kinds of inflammation that triggers much of the illness of aging — have already had intriguing success in mice.

Published in the journal Nature, a paper about the research undertaken by scientists at Imperial College London, Duke-NUS in Singapore, and the MRC Lab of Medical Sciences found that when given a drug that purges interleukin-11, the mice became more lean, had healthier fur, and had significantly lower levels of cancer than their counterparts of the same age.

A 64-year-old named Mark has spent the last year learning how to control devices like his laptop and phone using a brain implant. And thanks to OpenAI, it’s gotten a whole lot easier to do.

The neurotech startup Synchron said Thursday it’s using OpenAI’s latest artificial intelligence models to build a new generative chat feature for patients with its brain-computer interface, or BCI.

A BCI system decodes brain signals and translates them into commands for external technologies. Synchron’s model is designed to help people with paralysis communicate and maintain some independence by controlling smartphones, computers and other devices with their thoughts.