Lifeboat Foundation

How are synapses formed, those points of contact that allow the transmission of information from one neuron to the other? Working with an international team, researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have now uncovered a crucial mechanism and elucidated the identity of the axonal transport vesicles that generates synapses. The findings provide an important basis for promoting the regeneration of nerve cells and counteracting the aging process in the future. The results have just been published in the journal Science.

Whether in the brain or in the muscles, wherever there are nerve cells, there are synapses. These contact points between neurons form the basis for the transmission of excitation, i.e. communication between neurons. As in any communication process, there is a sender and a receiver: Nerve cell processes called axons generate and transmit electrical signals thereby acting as signal senders. Synapses are points of contact between axonal nerve terminals (the pre-synapse) and post-synaptic neurons. At these synapses, the electrical impulse is converted into chemical messengers that are received and sensed by the post-synapses of the neighboring neuron. The messengers are released from special membrane sacs called synaptic vesicles.

Toxins high-cite paper🤩

Title: ☎Dr. Sara Ragucci and Dr. Antimo Di Maro.

Read this review to have an overview of Mushrooms:

Continue reading “An Updated Review of Bioactive Peptides from Mushrooms in a Well-Defined Molecular Weight Range” »

Emmett Short discusses these comments on this episode of Lifespan News.

But first, the mad scientist David Sinclair, this time with Peter Diamandis at Abundance 360, giving more details into human trials for the genetic engineering side of the technology versus the chemical and pill side of the technology. Which would you want more? We’ll also hear David’s thoughts on how AI will affect the advancement of this tech. Spoiler: A lot. I’m going to play the best parts and add my commentary along the way.

When someone dies in the US, the vast majority of the time, their body is either embalmed, placed in a coffin, and buried in a cemetery, or cremated and the ashes returned to their loved ones in an urn — but those aren’t the only options.

A growing number of funeral directors, startups, and nonprofits are providing people with alternative ways to have their bodies honored after death — suggesting that the funeral landscape of tomorrow won’t be so binary.

Traditional burial and cremation has a cost for the environment, releasing chemicals into the ground or greenhouse gasses into the air, but a number of other funeral options are showing that death can be green.

Lung cancer is the third most common cancer in the U.S. and there have been more than 235,000 new cases of lung cancer in 2021. While this figure is significant, the rate of new lung and bronchus cancer cases is decreasing, in part because more people have stopped smoking. This trend, along with innovations in early detection and treatment, is also reducing the number of lung cancer deaths.

Dr. Robert Taylor Ripley, associate professor of surgery in the Division of General Thoracic Surgery, is an expert in mesothelioma and thoracic surgical oncology. In the following Q&A, he discusses common causes of lung cancer, risks and the latest treatments.

Q: What are the most common causes of lung cancer? A: Smoking cigarettes is the most common cause, but others include secondhand smoke and environmental inhalants. We see a fair number of patients with lung cancer who have never smoked. Exposure to diesel exhaust or other chemicals may also cause lung cancer in some non-smokers.

The Melanoma Treating Soap (MTS) was created using cancer-fighting chemicals, mainly Imidazoquinoline, integrated with a nanolipid-based particle transporter.

As child prodigies emerge in the world of innovation at younger ages than ever before, a 14-year-old student named Heman Bekele, residing in Fairfax, Virginia, developed a soap called MTS (Melanoma Treating Soap) to treat skin cancer.

Bekele’s efforts earned him the top prize in the 3M Young Scientist’s Challenge this year, a competition that motivates children to devise innovative solutions for common issues.

Nanotechnology sounds like a futuristic development, but we already have it in the form of CPU manufacturing. More advanced nanotech could be used to create independent mobile entities like nanobots. One of the main challenges is selecting the right chemicals, elements, and structures that actually perform a desired task. Currently, we create more chemically oriented than computationally oriented nanobots, but we still have to deal with the quantum effects at tiny scale.

One of the most important applications of nanotechnology is to create nanomedicine, where the technology interacts with biology to help resolve problems. Of course, the nanobots have to be compatible with the body (e.g. no poisonous elements if they were broken down, etc).

Continue reading “How nanobots and nanomedicine will improve our health” »

Regenerative medicine and tissue engineering strategies have made remarkable progress in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of three-dimensional (3D) scaffolds with appropriate biochemical and mechanical characteristics is critical for engineering tissue-engineered replacements. The extracellular matrix (ECM) is a dynamic scaffolding structure characterized by tissue-specific biochemical, biophysical, and mechanical properties that modulates cellular behavior and activates highly regulated signaling pathways. In light of technological advancements, biomaterial-based scaffolds have been developed that better mimic physiological ECM properties, provide signaling cues that modulate cellular behavior, and form functional tissues and organs.

OpenAI’s new preparedness team will address the potential dangers associated with AI, including nuclear threats.

OpenAI is forming a new team to mitigate the “catastrophic risks” associated with AI. In an update on Thursday.

The team will also work to mitigate “chemical, biological, and radiological threats,” as well as “autonomous replication,” or the act of an AI replicating itself. Some other risks that the preparedness team will address include AI’s ability to trick humans, as well as cybersecurity threats.

Continue reading “OpenAI forms new team to assess ‘catastrophic risks’ of AI” »