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Archive for the ‘genetics’ category: Page 13

Apr 19, 2019

Scientists restore some functions in a pig’s brain hours after death

Posted by in categories: biotech/medical, genetics, neuroscience

Circulation and cellular activity were restored in a pig’s brain four hours after its death, a finding that challenges long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death, Yale scientists report April 18 in the journal Nature.

The of a postmortem pig obtained from a meatpacking plant was isolated and circulated with a specially designed chemical solution. Many basic cellular functions, once thought to cease seconds or minutes after oxygen and blood flow cease, were observed, the scientists report.

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Apr 18, 2019

Dr. Doris Taylor — Texas Heart Institute — IdeaXme — Ira Pastor — “How to Build a New Heart”

Posted by in categories: 3D printing, aging, bioengineering, biotech/medical, chemistry, cryonics, DNA, genetics, health, life extension

Apr 17, 2019

CRISPR has been used to treat US cancer patients for the first time

Posted by in categories: biotech/medical, genetics

The gene-editing tool has been used in a trial to enhance the blood cells of two patients with cancer.

The trial: The experimental research, under way at the University of Pennsylvania, involves genetically altering a person’s T cells so that they attack and destroy cancer. A university spokesman confirmed it has treated the first patients, one with sarcoma and one with multiple myeloma.

Slow start: Plans for the pioneering study were first reported in 2016, but it was slow to get started. Chinese hospitals, meanwhile, have launched a score of similar efforts. Carl June, the famed University of Pennsylvania cancer doctor, has compared the Chinese lead in employing CRISPR to a genetic Sputnik.

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Apr 17, 2019

Discovery of oral cancer biomarkers could save thousands of lives

Posted by in categories: biotech/medical, genetics

Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that.

Researchers from the University of Otago and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different in tissues compared to the adjacent healthy tissues in patients.

Co-author Dr. Aniruddha Chatterjee, of Otago’s Department of Pathology, says finding these biomarkers is strongly associated with patient survival.

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Apr 17, 2019

Scientists reveal connection between cancer and human evolution

Posted by in categories: biotech/medical, evolution, genetics

Researchers at Ben-Gurion University of the Negev (BGU) have discovered that gene mutations that once helped humans survive may increase the possibility for diseases, including cancer.

The findings were recently the cover story in the journal Research.

The team of researchers from BGU’s National Institute for Biotechnology in the Negev (NIBN) set out to look for mutations in the genome of the , a part of every cell responsible for energy production that is passed exclusively from mothers to their children. The mitochondria are essential to every cell’s survival and our ability to perform the functions of living.

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Apr 16, 2019

First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway

Posted by in categories: biotech/medical, genetics, health

CRISPR Research Moves Out Of Labs And Into Clinics Around The World : Shots — Health News This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as cancer, blindness and sickle cell disease.

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Apr 14, 2019

Dr. Oliver Harrison MD, MPH, CEO, Telefonica Innovation Alpha — IdeaXme — Ira Pastor

Posted by in categories: aging, biotech/medical, business, computing, disruptive technology, genetics, health, information science, innovation, internet

Apr 13, 2019

How to biohack your cells to fight cancer — Greg Foot

Posted by in categories: bioengineering, biotech/medical, genetics

Check out the science of biohacking, where biologists go into a patient’s genetic code and reprogram their immune system to recognize and fight cancer cells.

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Apr 13, 2019

What Interesting Trends Are We Seeing In Genetics Research Right Now?

Posted by in category: genetics

What interesting trends are we seeing in genetics research right now? originally appeared on Quora: the place to gain and share knowledge, empowering people to learn from others and better understand the world.

Answer by Carrie Northover, Research Director at 23andMe, on Quora:

One of the coolest things right now is the size and scale of the research we’re able to do with human genetics, and those numbers are just getting bigger and bigger.

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Apr 12, 2019

Shutting down deadly pediatric brain cancer at its earliest moments

Posted by in categories: biotech/medical, genetics, neuroscience

Cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer allowed scientists to discover a molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer, glioblastoma.

Published findings in Cell Stem Cell describe how the single-cell analyses identified a subpopulation of cells critical to formation—the early primitive progenitor cells of oligodendrocyte cells, pri-OPC progenitors, according to Q. Richard Lu, Ph.D., lead investigator and Scientific Director of the Brain Tumor Center at Cincinnati Children’s Hospital Medical Center.

The data suggest that reprogramming of primitive oligodendrocyte progenitors into a stem-like state plays an important role in glioma initiation and progression. The researchers’ primary molecular target in the study, a protein called Zfp36l1, launches biological programs that mirror those of healthy early brain development in the mice, but instead help fuel brain cancer growth. The discovery presents an opportunity to find out if new therapeutic approaches can stop glioblastoma at its earliest stages of initial formation or recurrence, Lu said.

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