Lifeboat Foundation

For most of the time since the first description of multiple sclerosis (MS) in 1,868 the causes of this disabling disease have remained uncertain. Genes have been identified as important, which is why having other family members with MS is associated with a greater risk of developing the disease.

A recent study my colleagues and I conducted found that several types of infection during the teenage years are associated with MS after age 20. Our study didn’t investigate whether people who are more likely to have genetic risks for MS were also more likely to have worse infections.

This might explain why people with MS also have more infections that need hospital treatment.

Latest scientific findings suggest the ancestral Native American population does not originate in Japan, as believed by many archaeologists.

A widely accepted theory of Native American origins coming from Japan has been attacked in a new scientific study, which shows that the genetics and skeletal biology “simply does not match-up.”

The findings, published on October 12 2021, in the peer-reviewed journal PaleoAmerica, are likely to have a major impact on how we understand Indigenous Americans’ arrival to the Western Hemisphere.

Talking about RejuvenateBio starts at 20:30. Mentions there are 300 known genes concerning human aging and 45 of those have been tested in mice with what sounds like success.

Wow! Where do I start. I woke up and seen Dr. George Church on Bloomberg news. They was discussing a new biotech startup company called Rejuvenate Bio. A life extension company that seeks to reverse aging in dogs. Then apply that knowledge to humans. I ask Dr. Church about what he thinks is the cause of aging. t. Dr. Church thinks its a genetic reason why we age. Dr. Church is a cofounder of a company called Colossal is a company that wants to create a hybrid between the east asian elephant and the woolly mammoth. The purpose of doing this is to fight climate change and prevent the extinction of the east asian elephant.

Continue reading “Harvard University professor geneticist Dr. George Church stops by the Institute” »

The structural integrity of the brain’s white matter as measured with an advanced MRI technique is lower in cognitively normal people who carry a genetic mutation associated with Alzheimer’s disease than it is in non-carriers, according to a study in Radiology. Researchers said the findings show the promise of widely available imaging techniques in helping to understand early structural changes in the brain before symptoms of dementia become apparent.

People who carry the autosomal dominant Alzheimer disease (ADAD) mutation have a higher risk of Alzheimer’s disease, a type of dementia that affects about one in nine people in the United States. The mutation is linked to a buildup of abnormal protein called amyloid-beta in the brain that affects both the gray matter and the signal-carrying white matter.

“It’s thought that the amyloid deposition in the gray matter could disrupt its function, and as a result the white matter won’t function correctly or could even atrophy,” said study lead author Jeffrey W. Prescott, M.D., Ph.D., neuroradiologist at the MetroHealth Medical Center in Cleveland.

Researchers are trying to genetically reengineer people’s retinas to restore vision.

ORF Genetics in Iceland is growing 100,000 genetically engineered barley plants in a greenhouse measuring over 22 square feet (2 sq m) to create lab-grown meat.

This cutting-edge approach has the potential to lower prices, eliminate reliance on live animals in the lab-grown meat sector, and speed up the scaling-up process, according to BBC. And, with the fact that meat accounts for nearly 60 percent of all greenhouse gases from food production in mind, such a development could have far-reaching implications in the fight against climate change.

“Lower levels of DHA are associated with inflammation, cardiovascular and brain disorders, such as depression, which are all linked to migraine risk.”

Professor Nyholt said LPE(20:4) was a chemical compound that blocked the production of an anti-inflammatory molecule called anandamide.

Summary: Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.

Continue reading “Migraines Caused by Alterations in Metabolite Levels” »

Researchers in Iceland are growing over 100,000 genetically modified barley plants inside a greenhouse for a very unusual purpose: creating lab-grown meat, the BBC reports.

The altered barley gets harvested and purified to extract “growth factor” proteins, which, in turn, can be used to cultivate lab-grown meat — an innovation that could make the lab-grown meat industry rely even less on live animals in the future.

The company behind the greenhouse, ORF Genetics, is growing the biogenetically engineered barley over 22,000 square feet using high-tech hydroponic cultivation methods.

Circa 2019 o.o

The dream of resurrecting species like the woolly mammoth via genetic engineering is old enough that I remember reading articles about it in school 30 years ago. We may never be able to recover enough pristine genetic material from an intact woolly mammoth to make that approach feasible, but scientists working on the remains of the frozen mammoth known as Yuka have taken an incredible step nonetheless, demonstrating that at least some cell functions can remain intact after nearly 30,000 years.

Yuka, found in 2,010 is a juvenile woolly mammoth, considered to be the most intact and well-preserved mammoth ever found. That was critical to the researchers’ efforts — earlier tests in 2009 with a less-well-preserved but younger specimen at 15,000 years old yielded no positive results at all.

Continue reading “Scientists Revive 28,000-Year-Old Woolly Mammoth Cells in Mice” »